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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 30, 2024 | 3:23 PM IST
Amoxyclav 375 Tablet is used to treat bacterial infections of the ear, nose, throat, skin, bone, soft tissue, joints, urinary tract, and respiratory tract. It contains Amoxicillin and Clavulanic acid, which works by preventing the formation of bacterial cell covering, which is necessary for the survival of the bacteria. Thereby, it kills the bacteria. Also, it decreases bacterial resistance. In some cases, it may cause certain common side effects such as skin rashes, nausea, vomiting, bloating, and gas. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Abbott India Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Amoxyclav 375 Tablet

Amoxyclav 375 Tablet is an antibiotic medicine used to treat bacterial infections of the ear, nose, throat, skin, bone, soft tissue, joints, urinary tract, and respiratory tract. A bacterial infection is a condition in which harmful bacteria infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body.
 
Amoxyclav 375 Tablet is a combination of Amoxicillin and Clavulanic acid. Amoxicillin works by preventing the formation of bacterial cell covering, which is necessary for the survival of the bacteria. Thus, it kills the bacteria. Clavulanic acid works by decreasing bacterial resistance and enhancing the activity of amoxicillin against the bacteria. Together, Amoxyclav 375 Tablet helps in treating bacterial infections. 
 
Take Amoxyclav 375 Tablet as prescribed. The dose and duration of Amoxyclav 375 Tablet can vary depending on your condition and the severity of the infection. In some cases, you may experience certain common side effects, such as skin rashes, nausea, vomiting, bloating, and gas. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Amoxyclav 375 Tablet if you are pregnant or breastfeeding. Amoxyclav 375 Tablet may cause dizziness, so drive with caution. Avoid alcohol consumption while taking Amoxyclav 375 Tablet to prevent unpleasant side effects. Amoxyclav 375 Tablet is safe for children if prescribed by a doctor; the dose and duration may vary depending on the child’s weight and the severity of the infection. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects.

Uses of Amoxyclav 375 Tablet

Treatment of Bacterial Infections.

Medicinal Benefits

Amoxyclav 375 Tablet is a combination of Amoxicillin and Clavulanic acid. Amoxyclav 375 Tablet belongs to the group of medicines called antibiotics. Amoxyclav 375 Tablet is used to treat bacterial infections of the ear, nose, throat, skin, bone, soft tissue, joints, urinary tract, and respiratory tract. Amoxicillin works by preventing the formation of bacterial cell covering, which is necessary for the survival of the bacteria. Thus, it kills the bacteria. Clavulanic acid works by decreasing bacterial resistance and enhancing the activity of amoxicillin against the bacteria. Together, Amoxyclav 375 Tablet helps in treating bacterial infections. Amoxyclav 375 Tablet is a broad-spectrum antibiotic that is effective against both gram-positive and gram-negative bacteria.

Directions for Use

Swallow it as a whole; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Amoxyclav 375 Tablet

  • Skin rashes

  • Nausea

  • Vomiting

  • Bloating

  • Gas

Drug Warnings

Do not take Amoxyclav 375 Tablet if you are allergic to any of the contents or if you have jaundice. Inform your doctor if you have glandular fever, inflammation of the intestine, fits, liver/kidney problems or if you are unable to pass urine regularly. Consult your doctor before taking Amoxyclav 375 Tablet if you are pregnant or breastfeeding. Amoxyclav 375 Tablet may cause dizziness, so drive with caution. Avoid alcohol consumption while taking Amoxyclav 375 Tablet to prevent unpleasant side effects. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects.

Drug Interactions

Drug-Drug Interaction: Amoxyclav 375 Tablet may have interaction with anti-gout (allopurinol, probenecid), anticoagulants (warfarin), anti-cancer (methotrexate), and immunosuppressant (mycophenolate mofetil).

Drug-Food Interaction: No interactions found/established.

Drug-Disease Interaction: Amoxyclav 375 Tablet may have interactions with colitis (inflammation in the lining of the colon), mononucleosis (viral infection with sore throat and fever), haemodialysis, and liver and kidney dysfunction.

Drug-Drug Interactions Checker List

  • ALLOPURINOL
  • PROBENECID
  • WARFARIN
  • METHOTREXATE
  • MYCOPHENOLATE MOFETIL

Habit Forming

No

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help indigestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.

  • Eat fibre rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.

  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.

  • Avoid consumption of alcohol to treat your condition effectively.

  • Avoid usage of tobacco.

Special Advise

  • Amoxyclav 375 Tablet might affect blood and urine tests. Inform the person doing the tests that you are taking Amoxyclav 375 Tablet .

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue. Bacteria are of various forms, commonly spherical, rod-shaped, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Anyone can become infected with a bacterial infection. However, people with weak immune systems or taking immunosuppressive medicines are more prone to bacterial infection.

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Alcohol

Caution

Limit or avoid consuming alcohol while taking Amoxyclav 375 Tablet to prevent unpleasant side effects.

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Pregnancy

Caution

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

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Breast Feeding

Caution

This medication passes into breast milk. Consult your doctor before breast-feeding.

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Driving

Caution

Amoxyclav 375 Tablet may cause dizziness. So, drive only if you are alert and omit driving and operating machinery if you feel dizzy.

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Liver

Caution

Amoxyclav 375 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.

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Kidney

Caution

Amoxyclav 375 Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Caution

The dose and duration may vary depending upon the child’s weight and the severity of the infection.

Country of origin

India

Manufacturer/Marketer address

401, Lsc, C-Block, Mohan Place Saraswati Vihar Delhi Dl 110034 In
Other Info - AMO0202

Author Details

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FAQs

Amoxyclav 375 Tablet is used to treat bacterial infections of the ear, nose, throat, skin, bone, soft tissue, joints, urinary tract, and respiratory tract.
Amoxyclav 375 Tablet contains Amoxicillin and Clavulanic acid. Amoxicillin works by preventing the formation of bacterial cell covering, which is necessary for the survival of the bacteria. Thereby, it kills the bacteria. Clavulanic acid works by decreasing bacterial resistance and enhancing the activity of amoxicillin against the bacteria. Together, Amoxyclav 375 Tablet helps in treating bacterial infections.
No, this is an antibiotic medication. You need to complete the full course even if you start to feel better to prevent return of infection and resistance to Amoxyclav 375 Tablet .
Yes, Amoxyclav 375 Tablet is known to cause stomach upset, indigestion, nausea and diarrhoea. To avoid these side effects please take Amoxyclav 375 Tablet with a meal. Also, Amoxyclav 375 Tablet should be taken at evenly spaced intervals to avoid any unpleasant side effects and for best results.
Generally, penicillin group of antibiotics are not advised to be taken with methotrexate which is used for conditions like psoriasis, rheumatoid arthritis etc as they may cause some unpleasant side effects when taken together. However, Amoxyclav 375 Tablet is relatively safer to take with methotrexate but only if prescribed of the doctor. It is best to discuss with your doctor about the use of the two medicines together who may weigh the pros and cons and decide what is best for you.
Amoxyclav 375 Tablet does not treat a viral infection like the flu or a common cold. It is best to consult the doctor to know if you need Amoxyclav 375 Tablet for your condition.
Yes, after taking Amoxyclav 375 Tablet , you may have diarrhoea. So, drink plenty of fluids and take probiotics to prevent excessive loss of fluids from the body (dehydration). Do not take anti-diarrhoea medicine on your own, consult your doctor if the condition worsen.
Amoxyclav 375 Tablet may start to show its effects within a few hours after taking the medicine. However, you may begin to feel better after the first few days of treatment. If your symptoms do not improve or worsen, please contact your doctor.
Amoxyclav 375 Tablet should be taken for the duration prescribed by your doctor based on the severity of your infection. Usually, it is taken every 8-12 hours.
Amoxyclav 375 Tablet is generally safe when used as a doctor prescribes to treat bacterial infections. However, it may cause mild side effects, such as skin rashes, nausea, vomiting, bloating, and gas in some people. If you have any concerns about the safety of Amoxyclav 375 Tablet , please consult your doctor.
Amoxyclav 375 Tablet should not be taken by individuals allergic to any of its components or who have jaundice (yellowing of the skin). Inform your doctor if you have glandular fever, intestine inflammation, seizures, liver or kidney problems, or difficulty passing urine regularly.
Yes, the use of Amoxyclav 375 Tablet may reduce the effectiveness of hormonal contraceptives, such as birth control pills. This is because antibiotics like amoxicillin can affect the gut bacteria responsible for metabolizing contraceptive hormones, leading to lower hormone levels in the bloodstream. Please consult your doctor for alternative methods of preventing pregnancy or if you have any concerns while using this medication.
You should not exceed the recommended dose of Amoxyclav 375 Tablet , as doing so may increase the risk of side effects, such as stomach upset, liver damage, and allergic reactions. It may also lead to antibiotic resistance. If you feel that the current dose is ineffective or your infection worsens, please consult your doctor. Your doctor may adjust your dose or recommend an alternative treatment to prevent resistance.
Amoxyclav 375 Tablet should be stored at room temperature, away from direct sunlight. Keep it out of reach of children.
Amoxyclav 375 Tablet may cause allergic reactions in some individuals. Common symptoms of an allergic reaction include rash, itching, swelling, and difficulty breathing or swallowing. People who are allergic to penicillin (one of its ingredients) or other antibiotics in the same class are more likely to experience an allergic reaction. It is important to seek immediate medical attention if any signs of an allergic reaction occur.
Amoxyclav 375 Tablet does not commonly cause drowsiness as a side effect in some individuals. However, if you feel unusually tired after taking Amoxyclav 375 Tablet , please consult your doctor.
Amoxyclav 375 Tablet should be taken exactly as prescribed by your doctor. Typically, it should be swallowed as a whole with a glass of water. Do not crush, break, or chew it.
Do not take Amoxyclav 375 Tablet unless your doctor advises if you are pregnant or nursing. Please consult your doctor, as they will evaluate the benefits and risks and provide guidance tailored to your situation.
The common side effects of Amoxyclav 375 Tablet include skin rashes, nausea, vomiting, bloating, and gas. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Amoxyclav 375 Tablet may interact with certain medications, such as anti-gout drugs (e.g., allopurinol, probenecid), anticoagulants (e.g., warfarin), anti-cancer drugs (e.g., methotrexate), and immunosuppressants (e.g., mycophenolate mofetil). To ensure safe treatment, it is essential to inform your doctor about all the medications you are currently using, including supplements and over-the-counter drugs. Your doctor can help manage potential interactions and provide personalized guidance.
If you overdose on Amoxyclav 375 Tablet , seek immediate medical attention or go to your nearest emergency room. Overdose symptoms of Amoxyclav 375 Tablet may include nausea, vomiting, skin rash, drowsiness, diarrhoea, stomach pain, and decreased urination.

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