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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

Amitrip 10mg Tablet is used to treat depression, neuropathic pain, chronic tension-type headaches, and migraine in adults. Additionally, it is also used to treat bedwetting at night in children aged 6 years and above. It contains Amitriptyline, which works by affecting certain chemical messengers (serotonin, norepinephrine) in the brain, which communicate between brain cells, thereby helping in the regulation of mood and preventing depression. Besides this, it also lowers the transmission of pain signals, thereby providing relief from neuropathic pain. In some cases, you may experience certain common side effects such as sleepiness, drowsiness, headache, irregular heartbeat, dry mouth, constipation, nausea, weight gain, slurred or slow speech, and congested nose. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

AMITRIPTYLINE-10MG

Manufacturer/Marketer :

East West Pharma India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Amitrip 10mg Tablet

Amitrip 10mg Tablet is used to treat depression, neuropathic pain, chronic tension-type headaches, and migraine in adults. Additionally, Amitrip 10mg Tablet is also used to treat bedwetting at night in children aged 6 years and above. Depression is a mood disorder that affects a person's daily life described as feelings of sadness, loss, or anger. 

Amitrip 10mg Tablet contains Amitriptyline, which works by affecting certain chemical messengers (serotonin, norepinephrine) in the brain, which communicate between brain cells, thereby helping in the regulation of mood and preventing depression. Besides this, Amitrip 10mg Tablet also the transmission of pain signals, thereby providing relief from neuropathic pain.

You are advised to take Amitrip 10mg Tablet as long as your doctor has prescribed it for you, depending on your medical condition and response to the treatment. In some cases, you may experience certain common side effects such as sleepiness, drowsiness, headache, irregular heartbeat, dry mouth, constipation, nausea, weight gain, slurred or slow speech, and congested nose. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Amitrip 10mg Tablet for as long as your doctor has prescribed. Do not take Amitrip 10mg Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Amitrip 10mg Tablet causes drowsiness, sleepiness and dizziness; do not drive unless you are alert. Amitrip 10mg Tablet can be given to children over 6 years old if prescribed by the doctor for bedwetting. Amitrip 10mg Tablet should not be given to children for treating depression or neuropathic pain. Avoid consuming alcohol along with Amitrip 10mg Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Amitrip 10mg Tablet

Amitrip 10mg Tablet is used for the treatment of depression, neuropathic pain, chronic tension-type headaches, and migraine. The detailed uses of Amitrip 10mg Tablet are as follows:
•Depression Treatment: Amitrip 10mg Tablet is used to treat major depressive disorder by balancing neurotransmitters in the brain, which helps improve mood and relieve depression symptoms.
•Anxiety Disorders: Amitrip 10mg Tablet is also used to manage anxiety disorders, reducing symptoms of generalized anxiety, panic attacks, and other related conditions by promoting relaxation and mental well-being.
•Chronic Pain Management: Amitrip 10mg Tablet is used to manage chronic pain, particularly neuropathic pain conditions such as fibromyalgia and diabetic neuropathy, by changing how the brain processes pain signals.
•Migraine Prophylaxis: Amitrip 10mg Tablet is prescribed as a preventive treatment for migraines, helping to stabilize mood and reduce headache frequency, making it easier to manage migraine symptoms.
•Sleep Disorders: Amitrip 10mg Tablet sedative effects make it useful for treating insomnia and other sleep disorders, helping patients fall asleep faster and improving sleep quality.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew or crush the tablet/capsule. Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.

Medicinal Benefits

Amitrip 10mg Tablet belongs to a group of medicines called tricyclic antidepressants. Amitrip 10mg Tablet is used to treat depression, neuropathic pain, chronic tension-type headaches, and migraine in adults. Amitrip 10mg Tablet is also used to treat bedwetting at night in children aged 6 years and above. Amitrip 10mg Tablet works by affecting certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby helping in regulating mood and treating depression. Amitrip 10mg Tablet prevents the transmission of pain signals, thereby providing relief from neuropathic pain.

How Amitrip 10mg Tablet Works

Amitrip 10mg Tablet contains Amitriptyline, which works by affecting certain chemical messengers (serotonin, norepinephrine) in the brain, which communicate between brain cells, thereby helping in the regulation of mood and preventing depression. Besides this, Amitrip 10mg Tablet also the transmission of pain signals, thereby providing relief from neuropathic pain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Amitrip 10mg Tablet

  • Sleepiness
  • Drowsiness
  • Headache
  • Irregular heartbeat
  • Dry mouth
  • Constipation
  • Nausea
  • Weight gain
  • Slurred or slow speech
  • Congested nose

What if I have taken an overdose of Amitrip 10mg Tablet

Do not take more than the prescribed dose of Amitrip 10mg Tablet as it may cause overdose. The symptoms of overdose include irregular heartbeat, seizures (fits), confusion, coma, hallucination, drowsiness, or fever. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Amitrip 10mg Tablet if you are allergic to any of its contents if you recently had a heart attack, or heart problems, are taking other antidepressants like isocarboxazid, phenelzine, selegiline, tranylcypromine or have taken them in the last 14 days, have severe liver disease or if you have taken moclobemide (used to treat depression and social anxiety). Inform your doctor before taking Amitrip 10mg Tablet if you have heart rhythm problems or hypotension. Consult your doctor immediately if you have suicidal thoughts such as killing or harming yourself. Do not take Amitrip 10mg Tablet if you are pregnant or breastfeeding unless prescribed. Amitrip 10mg Tablet causes drowsiness and dizziness, do not drive unless you are alert. Amitrip 10mg Tablet can be given to children above 6 years if prescribed by the doctor for treating bedwetting. Amitrip 10mg Tablet should not be given to children for treating depression or neuropathic pain. Avoid consuming alcohol along with Amitrip 10mg Tablet as it could lead to increased drowsiness and dizziness. Rise slowly from sitting or lying position as Amitrip 10mg Tablet causes orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing).

Drug-Drug Interactions

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AmitriptylineSafinamide
Critical
AmitriptylineHalofantrine
Critical

Drug-Drug Interactions

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AmitriptylineSafinamide
Critical
How does the drug interact with Amitrip 10mg Tablet:
Using Amitrip 10mg Tablet together with Safinamide can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Safinamide and Amitrip 10mg Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Amitrip 10mg Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineHalofantrine
Critical
How does the drug interact with Amitrip 10mg Tablet:
Combining Amitrip 10mg Tablet and Halofantrine may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amitrip 10mg Tablet with Halofantrine may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineThioridazine
Critical
How does the drug interact with Amitrip 10mg Tablet:
Amitrip 10mg Tablet and Thioridazine can enhance each other's effects when used together.

How to manage the interaction:
Although using Amitrip 10mg Tablet and Thioridazine together can cause an interaction, they can be used if prescribed by a doctor. If you have extreme sleepiness, confusion, anxiety, vomiting, vision problems, feeling hot or cold, sweating, muscle stiffness, fainting, fits, or coma, seek medical help. Do not discontinue any medications without consulting a doctor.
AmitriptylineIsocarboxazid
Critical
How does the drug interact with Amitrip 10mg Tablet:
Combining Isocarboxazid with Amitrip 10mg Tablet can increase the risk of serotonin syndrome (increase serotonin hormone).

How to manage the interaction:
Although using Isocarboxazid and Amitrip 10mg Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Amitrip 10mg Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineFurazolidone
Critical
How does the drug interact with Amitrip 10mg Tablet:
Combining Furazolidone with Amitrip 10mg Tablet can increase the risk of serotonin syndrome(increased serotonin hormone).

How to manage the interaction:
Although using Furazolidone and Amitrip 10mg Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Amitrip 10mg Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineCisapride
Critical
How does the drug interact with Amitrip 10mg Tablet:
Coadministration of Amitrip 10mg Tablet and Cisapride may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amitrip 10mg Tablet with Cisapride may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineSparfloxacin
Critical
How does the drug interact with Amitrip 10mg Tablet:
Combining Amitrip 10mg Tablet and Sparfloxacin may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amitrip 10mg Tablet with Sparfloxacin may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor. Note: Sparfloxacin is no longer available in the market. Grepafloxacin should not be combined with any other medications.
AmitriptylinePimozide
Critical
How does the drug interact with Amitrip 10mg Tablet:
Combining Amitrip 10mg Tablet and Pimozide may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amitrip 10mg Tablet with Pimozide may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineLinezolid
Critical
How does the drug interact with Amitrip 10mg Tablet:
Taking Linezolid with Amitrip 10mg Tablet can increase the risk of serotonin syndrome (increased serotonin hormone).

How to manage the interaction:
Although using Linezolid and Amitrip 10mg Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Amitrip 10mg Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineRasagiline
Critical
How does the drug interact with Amitrip 10mg Tablet:
Using Amitrip 10mg Tablet together with Rasagiline can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Rasagiline and Amitrip 10mg Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Inform a doctor if you have recently taken Amitrip 10mg Tablet. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly helps in improving overall health and boosts self-esteem.

  • Regularly attend therapy sessions.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.

  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in proper maintenance of neurotransmitters. 

  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.

  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.

  • Avoid smoking and alcohol consumption.

  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Amitrip 10mg Tablet as it may cause an increased sedative effect.

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Pregnancy

Caution

Avoid taking Amitrip 10mg Tablet if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Amitrip 10mg Tablet ; your doctor will decide whether Amitrip 10mg Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Amitrip 10mg Tablet causes sleepiness, dizziness and drowsiness. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Amitrip 10mg Tablet can be given to children above 6 years if prescribed by the doctor for treating bedwetting. Amitrip 10mg Tablet should not be given to children for treating depression or neuropathic pain.

FAQs

Amitrip 10mg Tablet is used to treat depression, neuropathic pain, chronic tension-type headaches, and migraine in adults. Additionally, it is also used to treat bedwetting at night in children aged 6 years and above.

Amitrip 10mg Tablet works by affecting certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby helping regulate mood and treating depression.

Amitrip 10mg Tablet prevents the transmission of pain signals, thereby provides relief from neuropathic pain.

Amitrip 10mg Tablet causes sleepiness, drowsiness, and dizziness. Do not drive or operate machinery if you are experiencing these symptoms.

Amitrip 10mg Tablet causes weight gain due to increased appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight.

Country of origin

INDIA

Manufacturer/Marketer address

No. 10, 2nd Cross, Maravaneri, Salem - 636007, Tamil Nadu.
Other Info - AMI0103

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