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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Amgest 100mg Injection is used to treat Female Infertility, Amenorrhoea, Endometrial hyperplasia and Hormone replacement therapy (HRT). It contains progesterone, which is a female hormone. It helps regulate ovulation and menstruation in women. Progesterone induces secretory changes in the uterus's endometrium lining, promotes breast development, relaxes the uterus, blocks the maturation and release of a follicle, and maintains pregnancy.
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Manufacturer/Marketer

Health Biotech Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Amgest 100mg Injection

Amgest 100mg Injection belongs to the class of medicines known as hormones used as hormone replacement therapy in menopausal women who have not had a hysterectomy (surgery to remove the uterus). Amgest 100mg Injection is also used to treat periods/menstruation in women of childbearing age who have not reached menopause but stopped having periods. It is also used to treat endometrial hyperplasia and female infertility.

Amgest 100mg Injection contains progesterone which is a female hormone. It helps regulate ovulation and menstruation in women. Amgest 100mg Injection induces secretory changes in the endometrium lining of the uterus, promotes breast development, relaxes the uterus, blocks the maturation and release of a follicle, and maintains pregnancy.

Amgest 100mg Injection will be administered by a trained healthcare professional; hence do not self-administer. This medicine may cause certain side effects such as dizziness, headache, mood changes, constipation, diarrhea, bloating, heartburn, and injection site reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, consult your doctor immediately.

Amgest 100mg Injection should be avoided if you are allergic to it. This medicine may increase the risk of heart attack, stroke, blood clots, or breast cancer; therefore, inform your doctor if you have/had any of these conditions. Also, let your doctor know if you are pregnant or breastfeeding before administration of Amgest 100mg Injection. This medicine may cause dizziness and drowsiness, so it is advised to avoid driving or performing activities that require concentration. Keep your doctor informed about your health condition and all current and previous medications to rule out any side effects. Avoid alcohol consumption as it might cause increased dizziness and drowsiness.

Uses of Amgest 100mg Injection

Treatment of Female Infertility, Amenorrhoea, Endometrial hyperplasia and for Hormone replacement therapy (HRT)

Medicinal Benefits

Amgest 100mg Injection belongs to the class of medicines known as hormones used as hormone replacement therapy in menopausal women who have not had a hysterectomy (surgery to remove the uterus). Amgest 100mg Injection helps in initiating the menses cycle (periods) in women who have not yet reached menopause but have stopped getting their periods. Besides this, it also prevents overgrowth of the uterus in postmenopausal women who are using estrogen as hormone replacement therapy (HRT). Amgest 100mg Injection contains progesterone that regulates ovulation and menstruation in women. It induces secretory changes in the endometrium lining of the uterus, promotes breast development, relaxes the uterus, blocks the maturation and release of a follicle and maintains pregnancy.

Directions for Use

Amgest 100mg Injection will be administered by a trained healthcare professional; hence do not self-administer.

Side Effects of Amgest 100mg Injection

  • Abdominal pain
  • Abdominal bloating
  • Headache
  • Dizziness
  • Drowsiness
  • Headache
  • Injection site reactions
  • Breast tenderness

Drug Warnings

Amgest 100mg Injection should be avoided if allergic to it. Use of Amgest 100mg Injection with estrogens should be avoided as it may increase the chance of getting heart attacks, strokes, breast cancer, blood clots and dementia. Do not use Amgest 100mg Injection if you are allergic to peanuts, have unusual vaginal bleeding, have had any cancer (breast or uterus cancer), or undergoing estrogen plus progestin treatment. Tell your doctor before using Amgest 100mg Injection if you have had a heart attack, stroke, blood clot, liver problems, kidney problems, asthma (wheezing), epilepsy (seizures), diabetes, migraine, endometriosis, lupus, heart problems, thyroid or have high calcium levels in your blood. Consult your doctor if you are pregnant, breastfeeding or planning to get pregnant. Be cautious while driving as Amgest 100mg Injection may cause dizziness or drowsiness.

Drug Interactions

Drug-Drug Interactions: Amgest 100mg Injection may have an interaction with medicines, including anticonvulsants (carbamazepine),  herbal preparation (Ginkgo Biloba), etc.

Drug-Food Interactions: Avoid alcohol consumption and driving as it can cause dizziness.

Drug-Disease Interactions: Inform your doctor if you have breast cancer, liver/kidney disease, thromboembolism, depression, fluid retention (oedema), heart disease, retinal thrombosis (blocked vein of the retina of the eye), thyroid disease, high cholesterol (hyperlipidemia), uterine bleeding, ovarian cyst and weight gain (obesity).

Habit Forming

No

Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flushes and improve sleep.
  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take minimum sleep of 8 hours. 
  • Weight-bearing exercises can help in making your bone strong. Aerobics, yoga and activities like tai chi may help in relaxing the body and mind.
  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
  • Try to be stress-free to improve your mood swings due to hormonal fluctuations. 
  • Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.
  • Avoid consumption of alcohol as it can increase dizziness.

Special Advise

  • If you are scheduled for any laboratory tests, tell your health care professional that you are on treatment with Amgest 100mg Injection.
  • Amgest 100mg Injection is a parenteral form. It will be administered by your doctor, do not self-administer.

Disease/Condition Glossary

Female Infertility: It is a condition in which a woman is not able to become pregnant within a year of trying. If a woman gets pregnant but experiences miscarriages or stillbirths, it is also considered infertility.

Hormone replacement therapy (HRT): It is a treatment that replaces/boost hormones that are at a low level and helps relieve symptoms of menopause such as night sweats, hot flushes, vaginal dryness, mood swings, and reduced sex drive.

Amenorrhoea: It is the absence of more than three menstrual periods in a woman of childbearing age due to a lack of progesterone.

Endometrial hyperplasia: It is a condition where the uterus lining (endometrium) becomes unusually thick due to excessive cells (hyperplasia).

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Alcohol

Unsafe

Avoid consumption of alcohol as it may increase dizziness.

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Pregnancy

Unsafe

Amgest 100mg Injection is a Category B medicine. It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Amgest 100mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Clinical evidence suggests that Amgest 100mg Injection may pass into breast milk, but its risk is not established. Hence, if you are a nursing mother, inform your doctor before receiving Amgest 100mg Injection.

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Driving

Unsafe

Amgest 100mg Injection may cause dizziness and drowsiness. It is advised to avoid driving or operating machines after receiving this medicine.

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Liver

Unsafe

Amgest 100mg Injection is not recommended for use in liver impairment patients. Hence inform your doctor if you have liver disease or any concerns regarding this.

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Kidney

Caution

There is not enough scientific data available for Amgest 100mg Injection interaction with the kidney. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Amgest 100mg Injection is not recommended for children below 12 years of age as safety and efficacy have not been established.

Country of origin

India
Other Info - AM29894

FAQs

Amgest 100mg Injection is used to treat Female Infertility, Amenorrhoea, Endometrial hyperplasia and for Hormone replacement therapy (HRT).
Amgest 100mg Injection induces secretory changes in the endometrium lining of the uterus, promotes breast development, relaxes the uterus, blocks the maturation and release of a follicle and maintains pregnancy.
Do not use Amgest 100mg Injection if you are allergic to peanuts, have unusual vaginal bleeding, have had any cancer (breast or uterus cancer), or undergoing estrogen plus progestin treatment. Tell your doctor before using Amgest 100mg Injection if you had a heart attack, stroke, blood clot, kidney/liver problems, are pregnant, breastfeeding or planning to get pregnant or are allergic to Amgest 100mg Injection.
Amgest 100mg Injection helps in preparing the endometrium potential for pregnancy after ovulation. It thickens the lining of the endometrium to accept a fertilized egg. It also prevents muscle contractions of the uterus that would reject an egg in the uterus.
Abnormal uterine bleeding, irregular or missed periods (amenorrhea), abdominal pain during pregnancy, and frequent miscarriages are the signs of low progesterone. Additionally, low progesterone levels lead to high levels of estrogen, and women can have decreased sex drive, weight gain, or gallbladder problems.

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