Alprax Plus Tablet belongs to the class of medications called ‘antidepressant’ used in the treatment of panic disorder with or without agoraphobia (fear of leaving one’s own home or being in open or crowded places).  Panic disorder is characterized by a panic attack in which the patient experiences a sudden feeling of terror even if there is no real danger.

Alprax Plus Tablet contains Alprazolam and Sertraline. Alprazolam is a benzodiazepine. It works by increasing the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent). Thereby, Alprax Plus Tablet relaxes muscles, produces a calming effect, and helps to fall asleep. Sertraline is a selective serotonin reuptake inhibitor (SSRI). It increases the release of the serotonin hormone in the body, which is responsible for improving mood, cognition, and memory.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Alprax Plus Tablet are nausea (feeling sick), increased appetite, restlessness, drowsiness, dizziness, headache, constipation, dry mouth, jerks or uncoordinated movements, numbing or tingling sensation, vision problems, tinnitus (ringing in ears), ejaculation failure, and fatigue (extreme tiredness). Inform your doctor immediately if any of these side-effects persist or get worse.

It is not recommended to take Alprax Plus Tablet if you are allergic to any of its contents. Do not use Alprax Plus Tablet in patients with severe liver problems, severe breathing problems, myasthenia gravis (a muscle disorder), and if you have been taking monoamine oxidase inhibitors (MAOI) within 2 weeks. It is not recommended for use in children, pregnant women, and breastfeeding mothers. It should be used with caution in elderly people as dose adjustments are necessary. Do not consume alcohol as it may cause excessive drowsiness. Alprax Plus Tablet may cause drowsiness, so do not drive or operate heavy machinery if you are not fully alert.

Alprax Plus Tablet is used to treat panic disorder. It can restore the chemicals in the brain that can produce a calming effect and improve mood, energy and behavior. It also improves the overall well-being and quality-of-life of the patient. It can also help to sleep better. You should take this medicine as intended by the doctor for effective results.

• Nausea (feeling sick)
• Increased appetite
• Restlessness
• Drowsiness
• Dizziness
• Headache
• Constipation
• Dry mouth
• Jerks or uncoordinated movements
• Numbing or tingling sensation
• Vision problems
• Tinnitus (ringing in ears)
• Ejaculation failure
• Fatigue (extreme tiredness)

It is not recommended to use Alprax Plus Tablet concomitantly with monoamine oxidase inhibitors (MAOI), medicines used to treat mental illness, and opioid pain killers as it may cause serious side-effects. Before taking Alprax Plus Tablet , inform your doctor if you have mental illness, liver, lungs, or kidney problems, alcohol or drug abuse, eye problems, low sodium levels, diabetes, serotonin syndrome, and fits. Alprax Plus Tablet may cause suicidal thoughts and worsen depression or anxiety. So, it should be used with caution in patients with a history of suicidal tendencies and depression.

Drug-Drug Interactions: Alprax Plus Tablet should not be used concomitantly with monoamine oxidase inhibitor (MAOI) (isocarboxazid, phenelzine, selegiline, and moclobemide), MAOI like a drug (linezolid), a medicine used to treat psychosis (pimozide), opioid pain killers (morphine, codeine, and propoxyphene), antifungal drug (ketoconazole), oral contraceptives, antibiotics (erythromycin), a medicine used to treat stomach ulcer (cimetidine), a medicine used to treat high blood pressure and chest pain (diltiazem), a medicine used to treat heart disease (digoxin), and medicine used to treat HIV (ritonavir).

Drug-Food Interactions: Do not consume alcohol as it may cause excessive drowsiness.  

Drug-Disease Interactions: Alprax Plus Tablet should not be used in patients with severe liver problems, severe breathing problems, and myasthenia gravis (a muscle disorder).

• ISOCARBOXAZID
• PHENELZINE
• SELEGILINE
• MOCLOBEMIDE
• LINEZOLID
• PIMOZIDE
• MORPHINE
• CODEINE
• PROPOXYPHENE
• KETOCONAZOLE
• ERYTHROMYCIN
• CIMETIDINE
• DILTIAZEM
• DIGOXIN
• RITONAVIR

• Eat a well-balanced diet.
• Avoid processed or packed foods and foods that are high in refined sugars.
• Exercise regularly.
• Lose excess weight and keep a check on your weight.
• Avoid stress.
• Improve your mood by being active, socializing with others, and talking about your feelings.
• Quit alcohol intake and smoking.

• Do not stop the treatment abruptly as it can cause withdrawal reactions such as stomach cramps, muscle cramps, hallucinations (seeing or hearing things that are not real), and tremors, etc.
• Alprax Plus Tablet can be habit-forming. So, do not use it for a duration more than as intended by the doctor. 

Panic disorder: Panic disorder is a type of anxiety disorder. It is characterized by sudden panic attacks in which patients experience intense fear even if there is no real danger. During a panic attack, you get a rush of intense mental and physical symptoms. It can come on very quickly and for no apparent reason. A panic attack can be very frightening and distressing.