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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Alkof Orange Syrup is a combination medicine which belongs to the class of expectorants. It is used in the treatment of wet/productive cough. This medicine works by increasing the volume of fluid in the airways, reducing the stickiness of mucus, and removing it from the airways. Common side effects include nausea, diarrhoea, vomiting, stomach discomfort, sweating, muscle cramps, dizziness, and headache.
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Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Alkof Orange Syrup

Alkof Orange Syrup is used to treat cough associated with vicious and excessive mucus in patients with asthma and COPD (chronic obstructive pulmonary disorder). Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) produces mucous or sputum. 

Alkof Orange Syrup contains Guaifenesin, Bromhexine hydrochloride, Terbutaline sulphate and Menthol. Guaifenesin works by increasing the volume of fluid in the airways, thereby reducing the stickiness or viscosity of mucus. Bromhexine hydrochloride works by thinning and loosening phlegm (mucus) in the lungs, windpipe and nose, making it easier to cough it out. Terbutaline sulphate relaxes muscles and widens the airways making breathing easier. Menthol produces a cooling sensation and provides relief from minor throat irritation due to cough deposition.

Your doctor will recommend the dose and duration of Alkof Orange Syrup based on your medical condition. Some people may experience common side effects such as diarrhoea, nausea, vomiting, drowsiness, headache, dizziness, skin rash, tremor, stomach upset and fast heartbeats. Most of these side effects of Alkof Orange Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Consult your doctor if you are pregnant or planning for pregnancy. Avoid taking Alkof Orange Syrup while breastfeeding as it is excreted in breast milk and may cause adverse effects in the baby. Alkof Orange Syrup may cause dizziness, so drive or operate machinery only if you are alert. Alkof Orange Syrup should be used with caution in children, especially those below 2 years of age, if prescribed by a doctor. Keep your doctor informed about your health condition and medication to rule out any interactions.

Uses of Alkof Orange Syrup

Treatment of Cough

Directions for Use

Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Alkof Orange Syrup is a combination of four drugs, namely: Guaifenesin (expectorant), Bromhexine hydrochloride (mucolytic agent), Terbutaline sulphate (bronchodilator) and Menthol (cooling agent). Guaifenesin belongs to the class of expectorants that works by increasing the volume of fluid in the airways, thereby reducing the stickiness or viscosity of mucus and making it easier for airway passage. Bromhexine hydrochloride belongs to the class of mucolytic agents (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe and nose, making it easier to cough it out. Terbutaline sulphate belongs to the class of bronchodilators that relaxes muscles and widens the airways making breathing easier in people with respiratory complications. Menthol is a cooling agent that produces a cooling sensation and provides relief from minor throat irritation due to cough deposition. Together, Alkof Orange Syrup helps provide relief from cough.

How Alkof Orange Syrup Works

Alkof Orange Syrup contains Guaifenesin, Bromhexine hydrochloride, Terbutaline sulphate and Menthol. Guaifenesin works by increasing the volume of fluid in the airways, thereby reducing the stickiness or viscosity of mucus. Bromhexine hydrochloride works by thinning and loosening phlegm (mucus) in the lungs, windpipe and nose, making it easier to cough it out. Terbutaline sulphate relaxes muscles and widens the airways making breathing easier. Menthol produces a cooling sensation and provides relief from minor throat irritation due to cough deposition.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Alkof Orange Syrup

  • Diarrhoea
  • Nausea
  • Vomiting
  • Drowsiness
  • Headache
  • Dizziness
  • Stomach upset

What if I have taken an overdose of Alkof Orange Syrup

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include dizziness, confusion, and restlessness. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Consult your doctor if you are pregnant or planning for pregnancy. Avoid taking Alkof Orange Syrup while breastfeeding as it is excreted in breast milk and may cause adverse effects in the baby. Inform your doctor if you have diabetes, fits, high blood pressure, glaucoma, chronic bronchitis (swelling and irritation of the lining of airways), emphysema (lung condition resulting in shortness of breath), overactive thyroid, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), ulcers in the stomach or intestines, kidney, liver or heart problems.

Drug-Drug Interactions

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GuaifenesinProcarbazine
Severe
TerbutalineAmisulpride
Severe

Drug-Drug Interactions

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GuaifenesinProcarbazine
Severe
How does the drug interact with Alkof Orange Syrup 60 ml:
-

How to manage the interaction:
Co-administration of Alkof Orange Syrup 60 ml with Procarbazine can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
TerbutalineAmisulpride
Severe
How does the drug interact with Alkof Orange Syrup 60 ml:
Using Alkof Orange Syrup 60 ml together with amisulpride can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Amisulpride and Alkof Orange Syrup 60 ml can cause an interaction, but it can be taken if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
TerbutalineDisopyramide
Severe
How does the drug interact with Alkof Orange Syrup 60 ml:
The combined use of Alkof Orange Syrup 60 ml and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Alkof Orange Syrup 60 ml and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
TerbutalineNilotinib
Severe
How does the drug interact with Alkof Orange Syrup 60 ml:
Combining Alkof Orange Syrup 60 ml and nilotinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Alkof Orange Syrup 60 ml and nilotinib together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
TerbutalineSotalol
Severe
How does the drug interact with Alkof Orange Syrup 60 ml:
Using sotalol together with Alkof Orange Syrup 60 ml may reduce the benefits of both medications since they have opposing effects in the body.

How to manage the interaction:
Taking Sotalol with Alkof Orange Syrup 60 ml together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
TerbutalineCeritinib
Severe
How does the drug interact with Alkof Orange Syrup 60 ml:
Taking Alkof Orange Syrup 60 ml with ceritinib can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Ceritinib and Alkof Orange Syrup 60 ml, you can take these medicines together if prescribed by your doctor. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
TerbutalineEfavirenz
Severe
How does the drug interact with Alkof Orange Syrup 60 ml:
Taking Efavirenz and Alkof Orange Syrup 60 ml can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Efavirenz and Alkof Orange Syrup 60 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TerbutalineGatifloxacin
Severe
How does the drug interact with Alkof Orange Syrup 60 ml:
Taking Gatifloxacin and Alkof Orange Syrup 60 ml can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin and Alkof Orange Syrup 60 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TerbutalineLinezolid
Severe
How does the drug interact with Alkof Orange Syrup 60 ml:
Using Alkof Orange Syrup 60 ml together with linezolid may increase cardiovascular side effects (heart palpitations, chest pain, increased heart and pulse rates, and blood pressure elevations).

How to manage the interaction:
Although taking linezolid with Alkof Orange Syrup 60 ml together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you're diagnosed with a history of heart disease or high blood pressure, see your doctor before taking these medications. Do not discontinue any medication without consulting a doctor. Do not exceed the doses, frequency, or duration of usage advised by a doctor.
TerbutalineMoxifloxacin
Severe
How does the drug interact with Alkof Orange Syrup 60 ml:
Using moxifloxacin together with Alkof Orange Syrup 60 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Moxifloxacin and Alkof Orange Syrup 60 ml, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid dairy products such as milk, as it may increase mucus production. Also, avoid processed or refined foods.
  • Replace baked foods, fried foods, white bread, white pasta, french fries, sugary desserts and chips with green leafy vegetables.
  • Drink plenty of fluids to avoid a dry throat. It also helps loosen mucus.
  • Avoid citrus fruits as it may worsen the cough.
  • Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.

Habit Forming

No

Therapeutic Class

EXPECTORANT AND COUGH PRODUCTS

Alkof Orange Syrup Substitute

Substitutes safety advice
  • Cufdyn-Br 100Ml Syp

    by AYUR

    0.56per tablet
  • Alrex-B Syrup 100 ml

    0.68per tablet
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Alcohol

Caution

The interaction of alcohol with Alkof Orange Syrup is unknown. Please consult a doctor before consuming alcohol with Alkof Orange Syrup.

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Pregnancy

Unsafe

Alkof Orange Syrup is contraindicated in pregnant women, especially in the first 3 months of pregnancy, as it may cause birth defects. Therefore, please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Alkof Orange Syrup is excreted in breast milk and may cause adverse effects in the baby. Hence, it is not recommended for breastfeeding mothers.

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Driving

Caution

Alkof Orange Syrup may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Alkof Orange Syrup.

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Liver

Caution

If you have any concerns regarding the use of Alkof Orange Syrup in patients with liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns regarding the use of Alkof Orange Syrup in patients with kidney problems, please consult a doctor.

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Children

Caution

Alkof Orange Syrup should be used with caution in children, especially below 2 years of age, if prescribed by a doctor.

FAQs

Alkof Orange Syrup is used to treat cough associated with vicious and excessive mucus in patients with asthma and COPD (chronic obstructive pulmonary disorder).
Alkof Orange Syrup contains Guaifenesin, Bromhexine hydrochloride, Terbutaline sulphate and Menthol. Guaifenesin works by increasing the volume of fluid in the airways, reduce the stickiness of mucus and helps to remove it from the airways. Bromhexine hydrochloride works by thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Thereby, helps to cough out easily. Terbutaline sulphate relaxes muscles and widens the airways. Thereby, makes breathing easier. Menthol produces a cooling sensation and provides relief from minor throat irritation.
Alkof Orange Syrup may cause drowsiness or dizziness. It is not necessary for everyone taking Alkof Orange Syrup to experience this side effect. Avoid driving if you feel drowsy or dizzy after taking Alkof Orange Syrup.
Alkof Orange Syrup should be used with caution in diabetic patients if prescribed by a doctor. However, regular monitoring of blood sugar levels is recommended while taking Alkof Orange Syrup as it may increase blood sugar levels.
You are not recommended to take propranolol with Alkof Orange Syrup as it may reduce the effectiveness of both medicines. Also, propranolol may cause a narrowing of airways sometimes, which may trigger severe asthmatic attacks or worsen breathing problems. However, you should consult a doctor before taking other medicines with Alkof Orange Syrup.
Alkof Orange Syrup should be used with caution in hyperthyroid (overactive thyroid) patients as it may worsen the condition. Inform your doctor if you have hyperthyroidism so that the dose may be adjusted appropriately. However, regular monitoring of thyroid hormone levels is recommended while taking Alkof Orange Syrup.
You are recommended to take Alkof Orange Syrup for as long as your doctor has prescribed it. However, if the symptoms persist or worsen with rash, fever or persistent headache, please consult your doctor.
You are not recommended to stop taking Alkof Orange Syrup without consulting your doctor as it may worsen the cough or cause recurring symptoms. Therefore, take Alkof Orange Syrup for as long as your doctor has prescribed it, and if you experience any difficulty while taking Alkof Orange Syrup, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - ALK0079

Flavour

Orange

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