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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Alendrosiri Tablet is used in the prevention and treatment of osteoporosis and Paget’s disease of the bone. This medicine promotes bone integrity by regulating bone cell turnover and preventing bone cell destruction by suppressing the activity of osteoclasts. Common side effects include muscle or joint pain, nausea, indigestion, gas and headache.

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Manufacturer/Marketer :

Biosiri Life Sciences

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Alendrosiri Tablet

Alendrosiri Tablet belongs to the group of fortified bisphosphonates used in the prevention and treatment of osteoporosis and Paget’s disease of the bone. Osteoporosis is a condition in which bones become weak and brittle. Paget’s disease of the bone is a disorder in which the replacement of old bone cells by new bone cells is disrupted and dysregulated. 

Alendrosiri Tablet contains Alendronic acid, which promotes bone integrity by regulating bone cell turnover and preventing bone cell destruction by suppressing the activity of osteoclasts. Alendrosiri Tablet strengthens bones, thereby reducing the risk of fractures.

Take Alendrosiri Tablet as prescribed. In some cases, Alendrosiri Tablet may cause side effects such as muscle or joint pain, nausea, indigestion, gas and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen. 

It is advisable to inform the doctor if you are allergic to any of its components. Keep your doctor informed if you suffer from any oesophageal disorders, jaw problems, peptic ulcer disease, kidney disease, low blood calcium, low Vitamin D, if you are a smoker or have had a history of smoking, or if you have been immobilised for some time and are unable to sit upright. Consult your doctor if you are pregnant or breastfeeding. 

Uses of Alendrosiri Tablet

Alendrosiri Tablet is used to treat Osteoporosis and Paget's disease of the bone

Directions for Use

Take it on an empty stomach, preferably 30 minutes before food or beverages, for better absorption or take it as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it. Take it while sitting upright or standing. Try staying upright, and do not lie down for 30 minutes after taking it. Do not take it at bedtime or just before waking up.

Medicinal Benefits

Alendrosiri Tablet contains Alendronic acid, a bisphosphonate used to treat osteoporosis. It is used primarily to strengthen bones, joints, muscles and in the treatment of bone disease. Alendrosiri Tablet works by preventing bone destruction and resorption, thereby retaining the normal density of bones. It slows down the activity of bone-destroying cells (osteoclasts), which tend to be in overdrive in case of bone diseases such as osteoporosis and Paget’s. Hence, Alendrosiri Tablet is useful in strengthening and restoring the integrity and health of weak bones.

How Alendrosiri Tablet Works

Alendrosiri Tablet contains Alendronic acid, which promotes bone integrity by regulating bone cell turnover and preventing bone cell destruction by suppressing the activity of osteoclasts. Alendrosiri Tablet strengthens bones, thereby reducing the risk of fractures.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Alendrosiri Tablet

  • Muscle or joint pain
  • Nausea
  • Indigestion
  • Gas
  • Headache

What if I have taken an overdose of Alendrosiri Tablet

Never take more than the prescribed dose. Climatic skin, CNS depression, dysphagia, hiccups, miosis, respiratory depression, seizures, and wheezing are indications and symptoms of an overdose of Alendrosiri Tablet. For the treatment of voluntary overdose, supportive therapy and monitoring of urine flow, calcium levels, and phsophorous level are crucial.

Drug Warnings

Avoid taking Alendrosiri Tablet if you are allergic to any of its components. Inform your doctor if you suffer from any oesophageal disorders, jaw problems, peptic ulcer disease, kidney disease, low blood calcium, low Vitamin D, digestive problems, hyperparathyroidism, cancer, mouth infection, are on chemotherapy or radiotherapy, if you smoke, or if you have been immobilised for some time and are unable to sit upright. Keep your doctor informed if you have recently had any surgery or are about to undergo surgery or a dental procedure. Offer a detailed medical history and inform the doctor, especially if you are on steroids, antacids, antibiotics like gentamycin or amikacin, calcium supplements, laxatives containing magnesium, aspirin or any painkillers. Consult your doctor if you are pregnant or breastfeeding.

Drug-Drug Interactions

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Alendronic acidNaproxen
Severe
Alendronic acidEtelcalcetide
Severe

Drug-Drug Interactions

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Alendronic acidNaproxen
Severe
How does the drug interact with Alendrosiri Tablet 4's:
Co-administration of Naproxen with Alendrosiri Tablet 4's may increase the risk or severity of side effects.

How to manage the interaction:
Taking Naproxen with Alendrosiri Tablet 4's together can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you develop severe stomach pain, bloating, sudden dizziness, lightheadedness, vomiting (especially with blood), nausea, loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Alendronic acidEtelcalcetide
Severe
How does the drug interact with Alendrosiri Tablet 4's:
Co-administration of Alendrosiri Tablet 4's and Etelcalcetide may increase the risk of hypocalcemia (low levels of calcium).

How to manage the interaction:
Although taking Alendrosiri Tablet 4's and Etelcalcetide together can evidently cause an interaction, it can be taken if a doctor has suggested it. It's important to keep an eye on your calcium levels. Make sure to regularly check a blood calcium level and let a doctor know if you experience any symptoms like numbness, muscle spasms, or irregular heartbeat. They can help you if anything feels off. Do not stop using any medications without talking to a doctor.
Alendronic acidDeferasirox
Severe
How does the drug interact with Alendrosiri Tablet 4's:
Co-administration of Alendrosiri Tablet 4's (oral form) with Deferasirox may increase the risk of developing gastrointestinal ulcers.

How to manage the interaction:
Although there is a possible interaction between Alendrosiri Tablet 4's and Deferasirox, you can take these medicines together if advised by your doctor. However, if you develop severe stomach pain, bloating, sudden dizziness or lightheadedness, vomiting (especially with blood), nausea, loss of appetite, and/or black, tarry stools, contact your doctor immediately. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Load up on Vitamin D rich foods such as oily fish, egg yolks, spinach, broccoli, salmon and orange juice to promote bone health.
  • Stay hydrated by drinking plenty of water.
  • Doing weight-bearing exercises such as brisk walking, jogging, tennis, or even dance can be very useful in promoting overall bone health. However, do not over-exert yourself if you feel too tired or suffer from severely brittle bones. 
  • Muscle training activities such as yoga and Pilates can also be very helpful.
  • Spend time under the sun (however, with proper sunscreen) for quality intake of Vitamin D.
  • Limit alcohol and caffeine consumption and stop smoking as these may have a negative effect on bone health. Smokers tend to have lower bone density than non-smokers. 

Habit Forming

No

Therapeutic Class

BONE ENHANCERS

Alendrosiri Tablet Substitute

Substitutes safety advice
  • Osteofos 35 Tablet 4's

    38.38per tablet
  • Gatofos 35mg Tablet

    5.76per tablet
  • Gatofos 35 Tablet

    20.43per tablet
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Alcohol

Caution

Avoid consuming alcohol with Alendrosiri Tablet as it may cause increased dizziness. Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Alendrosiri Tablet is not indicated in pregnancy. Please consult your doctor if you have any concerns.

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Breast Feeding

Unsafe

Alendrosiri Tablet is not indicated in breastfeeding women. Please consult your doctor if you have any concerns.

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Driving

Caution

Alendrosiri Tablet usually does not affect your ability to drive. However, in rare cases, it may cause dizziness, muscle or bone pain. So, drive only if you are alert.

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Liver

Caution

Exercise caution before using Alendrosiri Tablet in case of established liver disease. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using Alendrosiri Tablet in case of established kidney disease. Please consult your doctor to address any concerns. Alendrosiri Tablet is not recommended for patients with renal impairment.

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Children

Unsafe

Alendrosiri Tablet is not recommended for use in children below. Please consult your doctor if you have any concerns.

FAQs

Alendrosiri Tablet is used in the prevention and treatment of osteoporosis and Paget’s disease of the bone.
Alendrosiri Tablet works by maintaining bone density. It helps in supporting bones and joints by inhibiting bone-destroying cells from being overactive.
Please see an orthopaedic doctor if you have had a fracture. Alendrosiri Tablet is used in the case of osteoporosis and has limited use in the direct treatment of fractures as a fracture is more of surgical concern.
It usually takes one month for Alendrosiri Tablet to start working. However, full benefits may take six months to one year to show.
Alendrosiri Tablet can be taken with other medicines if prescribed by the doctor. However, maintaining a gap of 30minutes between Alendrosiri Tablet and other medicines is advised.
Consult your doctor before taking NSAID's/pain killer medicines along with Alendrosiri Tablet.
Alendrosiri Tablet may cause osteonecrosis of the jaw. It is a bone disease in which there is a loss of blood to the bone. Maintain good oral hygiene, and have a regular dental check-up throughout the treatment with Alendrosiri Tablet. Consult your dentist if you experience any problems such as loose teeth, swelling, or pain.
You can help keep your bones healthy by making some fundamental lifestyle changes, including eating food for strong bones (foods high in calcium and vitamin D), Getting vitamin D from sunlight, Exercising (walking and low-impact aerobics are suitable for your bones), Stopping smoking, and Cutting down on alcohol.
You'll usually take Alendrosiri Tablet long term. Your doctor will then review your ongoing need for it. Your doctor will usually assess your risk of broken bones every 3 to 5 years. This may include tests to check your bones' strength (density). Depending on the results, you'll either keep taking Alendrosiri Tablet, take a break from it or stop taking it completely.
The best time to take your medicine is usually 30 minutes before you have breakfast. Take it on an empty stomach. Alendrosiri Tablet works best on an empty stomach because your body can absorb it properly.
Swallow it as a whole with water; do not crush, break or chew it. It's important to follow the instructions for this medicine very carefully.
Alendrosiri Tablet may cause has a side effect of causing hair loss. Consult your doctor if it persists.
Alendrosiri Tablet is not indicated in pregnancy. Please consult your doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

G.F.Rehai, P.O. Chaili, Shimla (H.P) - 171005
Other Info - ALE0263

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