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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Aldrex Plus Syrup is a combination medicine which belongs to the class of expectorants. It is used in the treatment of dry cough. This medicine works by preventing nerve signals from the brain's cough centre from reaching the muscles that cause coughing and thus reduce cough. You may experience common side effects like headache, dizziness, numbness, drowsiness, or nausea.
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About Aldrex Plus Syrup

Aldrex Plus Syrup is used to treat cough due to runny nose, sneezing, and throat irritation. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) produces mucous or sputum. 

Aldrex Plus Syrup is a combination of two drugs: Chlorphenamine maleate and Dextromethorphan hydrobromide. Chlorphenamine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions.  Dextromethorphan hydrobromide blocks the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Together, Aldrex Plus Syrup helps to relieve cough, cold and allergic symptoms. 

Your doctor will recommend the dose and duration of Aldrex Plus Syrup based on your medical condition. Some people may experience dry mouth/throat/nose, drowsiness, blurred vision, constipation, dizziness, and restlessness. Most of these side effects of Aldrex Plus Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or breastfeeding, it is advised to inform your doctor before starting Aldrex Plus Syrup. Aldrex Plus Syrup is not recommended for children below 2 years of age. Aldrex Plus Syrup may cause dizziness, so drive only if you are alert. Avoid alcohol consumption along with Aldrex Plus Syrup as it may cause increased dizziness and drowsiness. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Aldrex Plus Syrup

Treatment of Cough

Directions for Use

Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Aldrex Plus Syrup is a combination of two drugs: Chlorphenamine maleate (antihistamine) and Dextromethorphan hydrobromide (cough suppressant). Chlorphenamine maleate belongs to the class of antihistamines or anti-allergic that work by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Dextromethorphan hydrobromide belongs to the class of cough suppressants that block the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, together Aldrex Plus Syrup helps to relieve cough, cold and allergic symptoms.

How Aldrex Plus Syrup Works

Aldrex Plus Syrup is a combination of two drugs: Chlorphenamine maleate and Dextromethorphan hydrobromide. Chlorphenamine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions.  Dextromethorphan hydrobromide blocks the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Together, Aldrex Plus Syrup helps to relieve cough, cold and allergic symptoms.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Aldrex Plus Syrup

  • Dry mouth, throat or nose
  • Drowsiness
  • Blurred vision
  • Constipation
  • Dizziness
  • Restlessness

What if I have taken an overdose of Aldrex Plus Syrup

Avoid exceeding the recommended dose as it might cause an overdose. Seek medical attention if you experience any unusual symptoms.

Drug Warnings

Do not take Aldrex Plus Syrup if you are allergic to any of the contents. Avoid using Aldrex Plus Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine, and methylene blue injection in the past 14 days. It is advised to seek medical help if the cough does not go away or if it is followed by a high fever, skin rash, or persistent headache. Aldrex Plus Syrup may cause drowsiness, dizziness, and blurred vision in some patients; therefore, drive only if you are alert. Aldrex Plus Syrup should not be used in elderly patients with confusion. Avoid alcohol consumption along with Aldrex Plus Syrup as it might cause increased dizziness.

Drug-Drug Interactions

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DextromethorphanPargyline
Critical
DextromethorphanPhenelzine
Critical

Drug-Drug Interactions

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DextromethorphanPargyline
Critical
How does the drug interact with Aldrex Plus Syrup:
Co-administration of Pargyline and Aldrex Plus Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Aldrex Plus Syrup and Pargyline can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanPhenelzine
Critical
How does the drug interact with Aldrex Plus Syrup:
Co-administration of Phenelzine and Aldrex Plus Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Phenelzine and Aldrex Plus Syrup can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanIsocarboxazid
Critical
How does the drug interact with Aldrex Plus Syrup:
Co-administration of Isocarboxazid with Aldrex Plus Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Aldrex Plus Syrup and Isocarboxazid can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanTranylcypromine
Critical
How does the drug interact with Aldrex Plus Syrup:
Taking Tranylcypromine with Aldrex Plus Syrup can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Aldrex Plus Syrup with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
DextromethorphanSelegiline
Critical
How does the drug interact with Aldrex Plus Syrup:
Co-administration of Aldrex Plus Syrup and Selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Selegiline with Aldrex Plus Syrup can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DextromethorphanRasagiline
Critical
How does the drug interact with Aldrex Plus Syrup:
Taking Rasagiline with Aldrex Plus Syrup can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Aldrex Plus Syrup with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
DextromethorphanProcarbazine
Critical
How does the drug interact with Aldrex Plus Syrup:
Co-administration of Aldrex Plus Syrup and Procarbazine may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Procarbazine with Aldrex Plus Syrup can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
ChlorpheniraminePotassium chloride
Critical
How does the drug interact with Aldrex Plus Syrup:
Taking Aldrex Plus Syrup and Potassium chloride (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Aldrex Plus Syrup with Potassium chloride it not recommended as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor. Do not discontinue any medications without a doctor's advice.
ChlorpheniraminePotassium citrate
Critical
How does the drug interact with Aldrex Plus Syrup:
Taking Aldrex Plus Syrup and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Aldrex Plus Syrup with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
DextromethorphanCitalopram
Severe
How does the drug interact with Aldrex Plus Syrup:
Co-administration of Aldrex Plus Syrup and Citalopram may increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although there is a possible interaction between Aldrex Plus Syrup and Citalopram, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as seizures (fits), extreme changes in blood pressure, confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, tremors, incoordination, blurred vision, muscle spasm or stiffness, nausea, vomiting, stomach cramp, and diarrhea, contact a doctor immediately. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid dairy products such as milk as they may increase mucus production. Also, avoid processed or refined foods. Instead, replace baked foods, fried foods, white bread, white pasta, french fries, sugary desserts, and chips with green leafy vegetables.

  • Drink plenty of fluids to avoid a dry throat. It also helps loosen mucus.

  • Avoid citrus fruits as they may worsen the cough.

  • Eat fruits rich in water content, such as pears, watermelon, peaches, and pineapples.

Habit Forming

No

Therapeutic Class

COUGH AND COLD PREPARATIONS

Aldrex Plus Syrup Substitute

Substitutes safety advice
  • Quicktuss-DX Syrup

    0.80per tablet
  • Sogrest-DX Syrup Mix Fruit Sugar Free

    0.58per tablet
  • Abrox-D Syrup

    0.61per tablet
  • Addkuff DX Syrup

    1.03per tablet
  • Rexcold-DX Syrup

    0.58per tablet
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Alcohol

Unsafe

Aldrex Plus Syrup may increase the effects of alcohol, so it is advised to avoid alcohol consumption.

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Pregnancy

Caution

Consult a doctor if you have any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult a doctor if you have any concerns. Your doctor will decide if Aldrex Plus Syrup can be taken by breastfeeding mothers or not.

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Driving

Caution

Aldrex Plus Syrup may cause dizziness and drowsiness. Therefore, drive only if you are alert after taking Aldrex Plus Syrup.

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Liver

Caution

Take Aldrex Plus Syrup with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Aldrex Plus Syrup with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required in severe kidney disease.

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Children

Caution

Aldrex Plus Syrup is not recommended for children below 2 years of age. However, it can be used by children older than 2 years of age if prescribed by a child specialist.

FAQs

Aldrex Plus Syrup is used to treat cough due to runny nose, sneezing, and throat irritation.
Aldrex Plus Syrup contains Chlorphenamine maleate and Dextromethorphan hydrobromide. Chlorphenamine maleate blocks the action of histamine, a substance responsible for causing allergic reactions. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, decreasing the urge to cough.
Aldrex Plus Syrup may be used to relieve allergic symptoms such as sneezing, runny nose, throat irritation, or watery eyes. Aldrex Plus Syrup contains Chlorphenamine maleate, an anti-allergic drug that works by blocking the action of histamine, a substance responsible for causing allergic reactions.
Aldrex Plus Syrup may cause dry mouth as a temporary side effect in some people. It is not necessary for everyone taking Aldrex Plus Syrup to experience this side effect. However, to avoid such side effects, drink plenty of water, regularly rinse your mouth, practice good oral hygiene and suck on sugarless candy. However, if the condition persists or worsens, please consult a doctor.
You are recommended to take Aldrex Plus Syrup for as long as your doctor has prescribed it. However, if the symptoms persist or worsen even after one week of using Aldrex Plus Syrup, please consult your doctor.
It is advised not to stop taking Aldrex Plus Syrup without consulting your doctor as it may worsen the cough or cause recurring symptoms. Therefore, take Aldrex Plus Syrup for as long as your doctor has prescribed it, and if you experience any difficulty while taking Aldrex Plus Syrup, please consult your doctor.
Caution should be advised while using Aldrex Plus Syrup in people with Prostate problems. So, it should be taken only under the supervision of the doctor.
Aldrex Plus Syrup should not be taken along with medicines called monoamine oxidase inhibitors (MAOIs), which are used in the treatment of psychiatric illness.
Aldrex Plus Syrup is not recommended for children below 2 years of age. However, it can be used by children older than 2 years of age if prescribed by a child specialist.
Caution should be advised while using Aldrex Plus Syrup in people with eye problems. It should be taken only under the supervision of the doctor.
Yes, Aldrex Plus Syrup is a good option to treat dry cough.
Symptoms, such as cough and congestion, are usually relieved within 30 minutes to an hour of taking the Aldrex Plus Syrup, depending on the individual's response and the intensity of the symptoms.
Aldrex Plus Syrup is a combination of two drugs: Chlorphenamine maleate and Dextromethorphan hydrobromide.
No, taking more than the prescribed dose may not be more effective; it may raise the possibility of experiencing severe adverse reactions.
There is no substantial research yet on using Aldrex Plus Syrup in breastfeeding mothers. If you are a nursing mother, let your doctor know before taking Aldrex Plus Syrup; your doctor will decide whether breastfeeding mothers can take it or not.
Yes, Aldrex Plus Syrup may make you feel sleepier or drowsy.
Aldrex Plus Syrup is safe to use if the doctor prescribes it, but it has specific limitations.
No, Aldrex Plus Syrup is not an antibiotic medication. It is a combination of an antihistamine and an antitussive.
No, it is not recommended to treat fever. It is intended to treat cough.
Aldrex Plus Syrup should be taken for the duration prescribed by the doctor based on your condition. Usually, it is taken every 8-12 hours.
The timing of taking Aldrex Plus Syrup can vary depending on the specific instructions your healthcare professional provides.
Common side effects of Aldrex Plus Syrup may include dry mouth/throat/nose, drowsiness, blurred vision, constipation, dizziness, and restlessness. Most of these side effects of Aldrex Plus Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Other Info - ALDR527

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