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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 30, 2024 | 6:06 AM IST

Akurit Tablet is used to treat tuberculosis in children. It contains Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, they kill Mycobacterium tuberculosis, which causes TB (tuberculosis). Common side effects of Akurit Tablet are nausea, vomiting, diarrhoea, stomach pain, and loss of appetite.

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Prescription drug

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Prescription drug
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Consult Doctor

Manufacturer/Marketer

Lupin Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Akurit Tablet

Akurit Tablet is used to treat tuberculosis in children. Tuberculosis is an infectious disease that mainly affects the lungs but can also spread to other body parts such as the kidneys, brain, spine, and bone marrow.
 
Akurit Tablet contains Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, Akurit Tablet kills Mycobacterium tuberculosis which causes TB (tuberculosis).
 
In some cases, Akurit Tablet may cause side effects such as nausea, vomiting, diarrhoea, stomach pain, and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.
 
Let your doctor know if your child is allergic to any of the components in Akurit Tablet. Keep your doctor informed about your child's health condition and medications to rule out any side effects/interactions.

Uses of Akurit Tablet

Akurit Tablet is used in the treatment of Tuberculosis

Medicinal Benefits

Akurit Tablet belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis. Akurit Tablet contains two anti-mycobacterial agents, Rifampicin and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, Akurit Tablet kills Mycobacterium tuberculosis which causes TB (tuberculosis).

Directions for Use

Akurit Tablet should be given on an empty stomach, i.e., one hour prior or two hours after meals.Liquid: Administer the prescribed dose using a measuring cup/dosing syringe/dropper. Shake the bottle well before use.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Akurit Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Stomach pain
  • Loss of appetite

Drug Warnings

Do not give Akurit Tablet to the child if he/she is allergic to any of the components in Akurit Tablet, if he/she has acute liver disease, drug-induced liver disease, if the child has experienced liver damage linked to rifampicin or isoniazid, or if the child is taking anti-fungal (voriconazole) or medicines for HIV infection (protease inhibitors). Akurit Tablet may cause liver damage; consult your doctor if the child experiences symptoms such as unexplained loss of appetite, nausea, vomiting, jaundice, dark urine, persistent fatigue for more than 3 days, abdominal pain and tenderness. Consult a doctor if your child gets flu-like symptoms such as headache, fever, or muscle ache. Inform the doctor if your child has HIV infection, epilepsy, psychiatric disorder, diabetes, porphyria, phenylketonuria (metabolic disorder), peripheral neuropathy (tingling sensation in hands and feet), kidney or liver problems, if your child is allergic to ethionamide or niacin (nicotinic acid), or if your child is taking cortisone or any cortisone-like drug. 

Drug Interactions

Drug-Drug Interactions: Inform the doctor if your child is taking anti-fungal (voriconazole), HIV protease inhibitors (saquinavir, ritonavir), antacid (aluminium hydroxide), a medicine used to treat chronic alcoholism (disulfiram).

Drug-Food Interactions: Avoid foods such as cheese, tuna, tropical fish, or skipjack whilst on treatment with Akurit Tablet. Taking Akurit Tablet with cheese or fish may cause itching/redness of the skin, rapid/pounding heartbeat, headache, and light-headedness.

Drug-Disease Interactions: Inform the doctor if your child has acute liver disease or drug-induced liver disease.

Drug-Drug Interactions Checker List

  • VORICONAZOLE
  • SAQUINAVIR
  • RITONAVIR
  • DISULFIRAM

Habit Forming

No

Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Foods rich in vitamin C, such as kiwi, broccoli, and bell pepper, help improve the immune system. 
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help in providing relief from a cough.

Disease/Condition Glossary

Tuberculosis (TB): Tuberculosis is an infectious disease that affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease which can spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or with normal breathing, unexplained fatigue, fever, night sweats, loss of appetite and weight.

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Alcohol

Not applicable

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Pregnancy

Not applicable

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Breast Feeding

Not applicable

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Driving

Not applicable

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Liver

Consult your doctor

Please consult the doctor if your child has a liver impairment or if you have any concerns regarding this.

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Kidney

Consult your doctor

Please consult the doctor if your child has kidney problems.

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Children

Safe if prescribed

Akurit Tablet is safe for children if prescribed by the doctor. Your doctor may prescribe the dose and duration based on the child's condition and age.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - AKU0003

Author Details

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FAQs

Akurit Tablet is used to treat Tuberculosis.
Akurit Tablet works by killing Mycobacterium tuberculosis which causes TB (tuberculosis).
Akurit Tablet may cause reddish-orange discolouration of body fluids such as tears, sputum and urine; this is not harmful and does not require medical attention. However, consult your doctor if you have any concerns.
Akurit Tablet might stain soft contact lenses. The child should use spectacles and avoid wearing contact lens while taking Akurit Tablet.

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