Agonin 25mg Tablet is used for the treatment of depression and may also be used to prevent the relapse of depression symptoms. Major depressive disorder is a common and serious medical illness that negatively affects how you feel, the way you think and how you act. Fortunately, it is also treatable. Depression causes feelings of sadness and/or a loss of interest in activities.

Agonin 25mg Tablet contains 'Agomelatine', which works by altering the levels of certain chemicals in the brain, which helps in regulating the body clock (circadian natural cycle of physical, mental, and behavioural changes that the body goes through in a 24-hour cycle) with positive benefits on mood and sleep in patients suffering from depression.

Take Agonin 25mg Tablet as prescribed by your doctor. You are advised to take Agonin 25mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. You may experience headache, nausea, dizziness, fatigue, anxiety, insomnia (difficulty in sleeping), back pain, abdominal pain, change in body weight, diarrhoea, constipation, sleepiness, and Increased liver enzymes in some cases. Most of these side effects of Agonin 25mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, stop the medicine, and please consult your doctor.

If you are allergic to Agonin 25mg Tablet or any other medicines, please tell your doctor. Take the Agonin 25mg Tablet as advised by your doctor. Before taking Agonin 25mg Tablet, tell your doctor about the medicines which you are taking other than Agonin 25mg Tablet. Before taking Agonin 25mg Tablet, consult your doctor if you are pregnant/planning to get pregnant/breast-feeding women. Agonin 25mg Tablet should be used with caution in electroconvulsive therapy patients and kidney and liver patients as there is an increased risk of adverse effects. Agonin 25mg Tablet should be used with caution in elderly patients as there is an increased risk of adverse effects.

Agonin 25mg Tablet contains 'Agomelatine', which belongs to a class of antidepressants that works by altering the levels of certain chemicals in the brain. This helps regulate the body clock (circadian rhythm—the natural cycle of physical, mental, and behavioural changes that the body goes through in a 24-hour cycle) and has positive effects on mood and sleep in patients suffering from depression.

• Headache
• Nausea
• Dizziness
• Fatigue
• Anxiety
• Insomnia (difficulty in sleeping)
• Back pain
• Abdominal pain
• Change in body weight
• Diarrhea
• Constipation
• Sleepiness
• Increased liver enzymes
• Hallucinations
• Migraine like headache

If you are allergic to Agonin 25mg Tablet or any other medicines, please tell your doctor. Take the Agonin 25mg Tablet as advised by your doctor. Before taking Agonin 25mg Tablet, tell your doctor about the medicines which you are taking other than Agonin 25mg Tablet. Before taking Agonin 25mg Tablet, consult your doctor if you are pregnant/planning to get pregnant/breast-feeding women. Agonin 25mg Tablet should be used with caution in electro-convulsive therapy patients and kidney and liver patients as there is an increased risk of adverse effects. Agonin 25mg Tablet should be used with caution in elderly patients as there is an increased risk of adverse effects. If you have been taking this medicine for a long time, regular monitoring of blood and liver functions may be required. Be vigilant about unusual darkening or any changes in the colour of your urine, light-colored stools, yellowing of skin or eyes, pain in the upper right part of your stomach and unusual fatigue, as these could be signs of liver problems. It is important to inform your doctor if you develop any unusual changes in mood or behaviour, new or worsening depression or suicidal thoughts. Agonin 25mg Tablet should be used with caution in patients with a history of bipolar disorder, mania or hypomania and should be discontinued if a patient develops manic symptoms. Caution should be taken in non-alcoholic fatty liver disease, obese and alcoholic patients and smokers.

Drug-Drug Interaction: Agonin 25mg Tablet may have interaction with high blood pressure-lowering medicines (Propranolol), anti-depressant (fluvoxamine, moclobemide, nialamide, phenelzine), oestrogens, anti-TB (rifampicin), antibiotics (ciprofloxacin, enoxacin, linezolid).

Drug-Food Interaction: Avoid alcohol consumption with Agonin 25mg Tablet as it may increase the risk of severe adverse effects, including liver damage.

Drug-Disease Interaction: Agonin 25mg Tablet may interact with liver problems, dementia, and bipolar-disorders.

• CIPROFLOXACIN
• FLUVOXAMINE
• ENOXACIN
• RIFAMPICIN
• ESTROGEN
• PROPRANOLOL
• LINEZOLID
• MOCLOBEMIDE
• NIALAMIDE
• PHENELZINE

• Take fish, nuts, fresh fruits, vegetables, meat and dairy products.
• Do meditation, yoga and exercise regularly.
• Take carbohydrates like whole grains and legumes in your diet.
• Spend time with positive, supportive, loving people to help you through rocky times.
• Avoid alcohol
• Quit smoking

You may need regular blood tests to monitor your liver and kidney functions while you are taking this medication.

Major depression disorder, also referred to as clinical depression, is a significant medical condition that can affect many areas of your life. It impacts mood and behaviour as well as various physical functions. Symptoms include fatigue or loss of energy, feelings of worthlessness or guilt almost every day, impaired concentration, indecisiveness, insomnia or hypersomnia (excessive sleeping), restlessness or feeling slowed down, recurring thoughts of death or suicide, significant weight loss or gain (a change of more than 5% of body weight in a month). The exact cause of major depressive disorder isn’t known. However, there are several factors that can increase your risk of developing the condition, like genes, stress and hormonal imbalance.