Advan THF Cream is primarily used to treat melasma (dark brown patch on skin). Melasma, also known as chloasma or mask of pregnancy, is a common skin condition that causes brown patches on the face. It is more common in women than in men. The discoloured (grey-brown) patches occur mostly on the forehead, chin, nose and cheeks.

Advan THF Cream contains three medicines, namely: Fluocinolone acetonide (steroid), Hydroquinone (skin lightening or bleaching agent), and Tretinoin (a form of Vitamin A or retinoids). Fluocinolone acetonide is a steroid that blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy. Hydroquinone belongs to the class of skin-lightening agents that work by decreasing the amount of melanin (a skin pigment) that is responsible for the darkening of the skin. Tretinoin belongs to the class of retinoids (man-made vitamin A) that works by increasing the renewal of skin cells, which helps in the natural exfoliation of the skin’s outer layers.

Advan THF Cream is only for external use. Avoid contact of Advan THF Cream with nose, mouth, eyes, ears, or vagina. Do not apply on a cut, open wound, or burnt skin area. In case Advan THF Cream comes in contact with these areas accidentally, rinse with water thoroughly. Some people may experience application site reactions (burning, irritation, itching, and redness). Most of these side effects of Advan THF Cream do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Advan THF Cream or any other medicines, please tell your doctor. If you are pregnant, nursing mother or planning for pregnancy, it is advised to consult a doctor before using Advan THF Cream. Advan THF Cream is not recommended for children below 12 years of age. Do not apply Advan THF Cream on ulcerated skin or wounds. Avoid sun exposure while using Advan THF Cream as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. Do not cover or wrap the treated area with a bandage unless advised by your doctor. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) that is in contact with Advan THF Cream catches fire and burns easily. If you have a sulfite allergy, asthma, rosacea (redness and often red, small, pus-filled bumps on the face), acne, skin thinning, perioral dermatitis (redness and swelling of the skin around the mouth), genital itching, chickenpox, diabetes, cold sores, ulcerated skin, warts, shingles (a viral infection causing painful rash), eczema (itchy, swelling of the skin) or any other skin condition, diabetes, Cushing syndrome, glucosuria, inform your doctor before taking Advan THF Cream.

Advan THF Cream contains three medicines, namely: Fluocinolone acetonide (steroid), Hydroquinone (skin lightening or bleaching agent) and Tretinoin (a form of Vitamin A or retinoids) used to treat melasma. Fluocinolone acetonide is a steroid that blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Hydroquinone belongs to the class of skin lightening agents that works by decreasing the amount of melanin (a skin pigment) that is responsible for the darkening of the skin. Tretinoin belongs to the class of retinoids (man-made vitamin A) that works by increasing the renewal of skin cells, which helps in the natural exfoliation of skin’s outer layers.

•  Burning
•  Irritation
•  Itching  
•  Redness

If you are allergic to Advan THF Cream or any other medicines, please tell your doctor. If you are pregnant, nursing mother, or planning for pregnancy, it is advised to consult a doctor before using Advan THF Cream. Advan THF Cream is not recommended for children below 12 years of age. Do not apply Advan THF Cream on ulcerated skin or wounds. Avoid sun exposure while using Advan THF Cream as it may make the skin more sensitive to sunlight and cause sunburn. Do not cover or wrap the treated area with a bandage unless advised by your doctor. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) that is in contact with Advan THF Cream catches fire and burns easily. If you have a sulfite allergy, asthma, have rosacea (redness and often red, small, pus-filled bumps on the face), acne, skin thinning, perioral dermatitis (redness and swelling of the skin around the mouth), genital itching, chickenpox, diabetes, cold sores, ulcerated skin, warts, shingles (a viral infection causing painful rash), eczema (itchy, swelling of the skin) or any other skin condition, diabetes, Cushing syndrome, glucosuria, inform your doctor before taking Advan THF Cream. inform your doctor before taking Advan THF Cream.

Drug-Drug Interaction: No interactions found.

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: No interactions found.

• Avoid sun exposure while using Advan THF Cream as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.

• Regular exercise can improve your mood and self-esteem though it doesn’t clear spots. Take a shower immediately after finishing the exercise.

• Wear a wide-brimmed hat to protect your face from sun exposure.

• Avoid using skin products that cause irritation such as skin cleansers or shampoos, harsh soaps, hair removers or waxes, hair colours or permanent chemicals, skin products with astringents, lime, spices, or alcohol.

• Avoid using Advan THF Cream for more than 6-8 weeks without a doctor’s advice.

• Please consult a dermatologist if the skin condition does not improve after 2-3 months of treatment with Advan THF Cream.

• Do not take Advan THF Cream by mouth. Advan THF Cream is for use only on the skin (topical use). Accidently if Advan THF Cream gets in your eyes or mouth, immediately rinse with cold water.

• Do not take Advan THF Cream if you allergic sulfa containing medicines and have asthma. It is better to contact a doctor in these conditions and take Advan THF Cream. 

Melasma: It is also known as chloasma, a common skin condition that causes brown patches on the face. The discoloured (grey-brown) patches occur mostly on the forehead, chin, nose, and cheeks. Melasma may be caused due to sun exposure, hormone therapy, pregnancy, birth control pills, thyroid or even stress. It is more common in women than in men. It may occur in pregnant women due to hormonal changes during pregnancy and is called a ‘mask of pregnancy and fades away after pregnancy on its own or after stopping the usage of contraceptive pills. It can be treated by using skin-lightening creams, topical steroids, dermabrasion or chemical peels.