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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:19 PM IST

Adpem 100Mg Injection is used to treat Non-small cell lung cancer and malignant pleural mesothelioma. It contains Pemetrexed, which treats cancer by blocking the action of substances that may help the cancer cells multiply. Do not use this medication if you are pregnant or breastfeeding. Women and men should use effective contraception during treatment with Adpem 100Mg Injection and for 6 and 3 months afterwards. It is not recommended for children below 18 years.

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Composition :

PEMETREXED-100MG

Manufacturer/Marketer :

Adley Formulations

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Adpem 100Mg Injection

Adpem 100Mg Injection belongs to the group of medicines called folate analogue metabolic inhibitors used alone or in combination with other anti-cancer medicines to treat non-small cell lung cancer and malignant pleural mesothelioma (cancer affecting the lining of the lung).

Adpem 100Mg Injection contains Pemetrexed, which works by blocking the action of substances that may help the cancer cells multiply.

In some cases, Adpem 100Mg Injection may cause side effects such as diarrhoea, tiredness, nausea, vomiting, and loss of appetite. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Do not use Adpem 100Mg Injection if you are pregnant or breastfeeding. Adpem 100Mg Injection is not recommended for children below 18 years. Women and men should use effective contraception during treatment with Adpem 100Mg Injection and for 6 and 3 months afterwards. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Adpem 100Mg Injection

Treatment of Non-small cell lung cancer and malignant pleural mesothelioma

Medicinal Benefits

Adpem 100Mg Injection contains Pemetrexed, which belongs to the group of medicines called anti-folate anti-neoplastic agents indicated in the treatment of malignant pleural mesothelioma and non-small cell lung cancer in initial treatment in combination with cisplatin, as maintenance treatment of patients whose disease has not progressed after four cycles of platinum-based first-line chemotherapy and after prior chemotherapy as a single agent. Adpem 100Mg Injection treats cancer by blocking the action of substances that may help the cancer cells multiply.

Side Effects of Adpem 100Mg Injection

  • Nausea
  • Vomiting
  • Loss of appetite
  • Tiredness
  • Pain, redness, swelling or sores in the mouth
  • Infection
  • Sore throat
  • Low white blood cells, haemoglobin levels
  • Skin rash
  • Flaking skin

Directions for Use

Adpem 100Mg Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not use Adpem 100Mg Injection if you are allergic to any of its components, pregnant or breastfeeding, or if you have taken or plan to receive yellow fever vaccination. Inform the doctor if you have/had heart disease, kidney problems, have had or are going to have radiation therapy, or have accumulation of fluid around the lungs. Seek immediate medical attention if you experience symptoms of fever or infection; pain, sores, redness or swelling in the mouth; chest pain or a fast heartbeat; allergic reaction (skin rash, burning/prickling sensation, or fever); Stevens-Johnson Syndrome or toxic epidermal necrolysis (severe rash, itching, or blistering); low haemoglobin levels (tiredness, feeling faint, paleness, or becoming easily breathless); low platelet count (bleeding from gums/nose/mouth, bleeding that does not stop, unexpected bruising, reddish or pinkish urine); or blood clot in the blood vessels of the lungs (sudden breathlessness, cough with bloody sputum or intense chest pain).

Therapeutic Class

CHEMOTHERAPY

Drug-Drug Interactions

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PemetrexedTofacitinib
Severe
PemetrexedInfliximab
Severe

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried, processed food, refined carbs, and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods, vegetables and fruits.

Habit Forming

No

What if I have taken an overdose of Adpem 100Mg Injection

Since Adpem 100Mg Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.
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Alcohol

Consult your doctor

It is not known if alcohol affects Adpem 100Mg Injection. Please consult your doctor.

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Pregnancy

Unsafe

Pemetrexed belongs to pregnancy category D. The use of Adpem 100Mg Injection should be avoided during pregnancy as it might harm the unborn baby.

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Breast Feeding

Unsafe

Breastfeeding must be discontinued during treatment with Adpem 100Mg Injection.

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Driving

Caution

Adpem 100Mg Injection may cause tiredness. Caution is advised while driving or operating heavy machinery.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving Adpem 100Mg Injection.

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Kidney

Caution

Dose adjustment may be needed. If you have a history of kidney disease, inform your doctor before receiving Adpem 100Mg Injection.

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Children

Unsafe

Adpem 100Mg Injection is not recommended for children below 18 years as safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Adley Formulation, SCO- 42, Sector 12, Panchkula-134112, Haryana, India
Other Info - ADP0025

Author Details

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FAQs

Adpem 100Mg Injection is used to treat Non-small cell lung cancer and malignant pleural mesothelioma.
Adpem 100Mg Injection works by blocking the action of substances that may help the cancer cells multiply.
Adpem 100Mg Injection may affect your ability to have children. Seek advice from the doctor about sperm storage before initiation of therapy. Use effective contraception and avoid fathering a child during treatment and for up to 3 months afterwards.
Adpem 100Mg Injection may suppress bone marrow suppression, resulting in cytopenia (low white blood cells, red blood cells, or platelets) and increased risk of infection. The doctor may adjust the dose based on the blood cell count and non-hematologic toxicity.
To lower the chances of side effects during anticancer treatment, your doctor may prescribe supplements like folic acid and vitamin B12 prior to and during treatment with Adpem 100Mg Injection.
No, Adpem 100Mg Injection is not a vesicant (irritant).
Adpem 100Mg Injection is safe when used as per the dose and duration advised by a doctor.
Yes, Adpem 100Mg Injection may cause hair loss as its side effect. If you have any concerns, contact your doctor.
Adpem 100Mg Injection causes side effects such as nausea, vomiting, loss of appetite, tiredness, pain/redness/swelling/ sores in the mouth, sore throat, skin rash, hair loss and low white blood cells. These side effects do not require medical attention and will gradually reduce over time. Please, contact a doctor if these persist or worsen.

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Keep Refrigerated. Do not freeze.