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Adnohep 300mg Tablet is used to treat gallstones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in bile and children above 6 years with biliary and liver diseases caused by cystic fibrosis. It contains Ursodeoxycholic acid, which helps decrease the production of cholesterol in the blood, thereby dissolving gall bladder stones composed mainly of cholesterol. It has a protective effect on the liver cells. Thus, it protects from injury caused by toxic bile acids and improves liver function. In some cases, you may experience certain common side effects such as abdominal discomfort, abdominal pain, diarrhoea, nausea, rash, dizziness, indigestion and weakness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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About Adnohep 300mg Tablet
Adnohep 300mg Tablet belongs to a group of medicines called biliary agents or gallstone dissolution agents. These agents are used to treat gallstones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in the bile, and children above 6 years old with biliary and liver diseases caused by cystic fibrosis.
Adnohep 300mg Tablet contains ursodeoxycholic acid, which is a naturally occurring bile acid. Adnohep 300mg Tablet helps decrease the production of cholesterol in the blood, thereby dissolving gallbladder stones composed mainly of cholesterol. Adnohep 300mg Tablet has a protective effect on the liver cells from injury caused by toxic bile acids and improves liver function.
Take Adnohep 300mg Tablet with food. You are advised to take Adnohep 300mg Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as abdominal discomfort, abdominal pain, diarrhoea, nausea, rash, dizziness, indigestion and weakness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Inform your doctor before taking Adnohep 300mg Tablet if you have variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), liver encephalopathy or liver disease. Do not take Adnohep 300mg Tablet if you are pregnant or breastfeeding unless prescribed. Adnohep 300mg Tablet can be given to children above 6 years if prescribed by the doctor. Avoid consuming alcohol along with Adnohep 300mg Tablet as it could lead to increased drowsiness and liver damage. Keep your doctor informed about your health condition and medicines to rule out any side effects.
Uses of Adnohep 300mg Tablet
Directions for Use
Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule. Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper; shake the pack well before each use. Dispersible tablet: Disperse the tablet in water and consume it.
Medicinal Benefits
Adnohep 300mg Tablet contains ursodeoxycholic acid, which is a naturally occurring bile acid. It belongs to a group of medicines called the biliary agent or gallstone dissolution agents used to treat gallstones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in bile children above 6 years with biliary and liver diseases caused by cystic fibrosis. Adnohep 300mg Tablet breaks down the cholesterol that has formed into gall bladder stones, thereby dissolving the stones. Adnohep 300mg Tablet has a protective effect on the liver cells and the immune system, thereby improving liver function. Adnohep 300mg Tablet decreases the amount of cholesterol produced by the liver and absorbed by the intestine. In patients with primary biliary cirrhosis, Adnohep 300mg Tablet increases the bile flow.
How Adnohep 300mg Tablet Works
Storage
Side Effects of Adnohep 300mg Tablet
What if I have taken an overdose of Adnohep 300mg Tablet
Drug Warnings
Do not take Adnohep 300mg Tablet if you are allergic to any of its contents, if you have inflammation of gall bladder and bile ducts, narrowing or blockage of bile ducts, biliary colic, calcified gallstones, improper constriction of the gallbladder, gastric or duodenal ulcer. Inform your doctor before taking Adnohep 300mg Tablet if you have variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), liver encephalopathy or liver disease. Consult your doctor before taking Adnohep 300mg Tablet with other medicines as Adnohep 300mg Tablet might reduce the absorption of antibiotics (ciprofloxacin and dapsone) and antihypertensive agents (nitrendipine), increase the effect of immunosuppressants (cyclosporine), oral contraceptives (oestrogen) and cholesterol-lowering agents (clofibrate) might promote the formation of gallstones. Do not take Adnohep 300mg Tablet if you are pregnant or breastfeeding unless prescribed. Adnohep 300mg Tablet can be given to children above 6 years if prescribed by the doctor. Avoid consuming alcohol along with Adnohep 300mg Tablet as it could lead to increased drowsiness and liver damage. Keep your doctor informed about your health condition and medicines to rule out any unpleasant side effects.
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Alcohol
Unsafe
Avoid consumption of alcohol while taking Adnohep 300mg Tablet as it may cause increased dizziness and liver damage.
Pregnancy
Caution
Adnohep 300mg Tablet belongs to pregnancy category B. Please consult your doctor if you have any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
Caution
Consult your doctor before taking Adnohep 300mg Tablet; your doctor will decide whether breastfeeding mothers can take Adnohep 300mg Tablet or not.
Driving
Caution
Adnohep 300mg Tablet does not affect your ability to drive. However, you are advised to be cautious while driving if you experience dizziness.
Liver
Caution
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
Caution
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Caution
Adnohep 300mg Tablet can be given to children with caution above 6 years and only if prescribed by the doctor.
Adnohep 300mg Tablet is used to treat gallstones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in bile and children above 6 years with biliary and liver diseases caused by cystic fibrosis.
Adnohep 300mg Tablet works in decreasing the production of cholesterol and by dissolving the cholesterol in bile, thereby preventing the formation of gallstones. Adnohep 300mg Tablet decreases the toxic levels of bile acids that accumulate in primary biliary cirrhosis.
Do not discontinue Adnohep 300mg Tablet without consulting your doctor. To treat your condition effectually, continue taking Adnohep 300mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you have any difficulty taking Adnohep 300mg Tablet.
Diarrhoea might be a side-effect of Adnohep 300mg Tablet. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Avoid taking aluminium-containing antacids along with Adnohep 300mg Tablet, as they might interfere with its absorption. Maintain a gap of 2 hours between both.
Adnohep 300mg Tablet might reduce the absorption of antibiotics (ciprofloxacin and dapsone) and antihypertensive agents (nitrendipine). Adnohep 300mg Tablet might increase the effect of immunosuppressants (cyclosporine). Cholesterol-lowering agents (clofibrate) might promote the formation of gallstones. Inform your doctor before taking Adnohep 300mg Tablet with other medicines to avoid unpleasant side effects.
Oral contraceptives (oestrogen) might promote the formation of gallstones. Consult your doctor if you have any concerns regarding this, your doctor may advise other contraception methods.
There is no evidence that Adnohep 300mg Tablet affects fertility. Please consult the doctor if you have any concerns regarding this.
Adnohep 300mg Tablet should be given to paediatric patients only if prescribed by the doctor. It may be used in children above 6 years with liver and biliary diseases caused by cystic fibrosis.
The doctor will determine when to take Adnohep 300mg Tablet based on your condition. Adnohep 300mg Tablet should be taken after a meal with a glass of milk or a small snack. Take the prescribed number of tablets distributed throughout the day as advised by the physician.
Yes, Adnohep 300mg Tablet is safe to use if prescribed by the doctor. Like all medicines, Adnohep 300mg Tablet may also cause side effects in some people. However, if any of the side effects are bothersome, please consult the doctor.
Adnohep 300mg Tablet has a protective effect on the liver cells from injury caused by toxic bile acids and improves liver function.
Adnohep 300mg Tablet may cause weight gain in some people. Consult the doctor if you notice rapid weight gain, especially in your face and midsection.
Avoid taking other medicines concomitantly with Adnohep 300mg Tablet as it might reduce or intensify the effect of other medicines. Colestyramine and colestipol should be taken 2 hours before or after Adnohep 300mg Tablet. Consult your doctor before taking Adnohep 300mg Tablet with other medicines as Adnohep 300mg Tablet might reduce the absorption of antibiotics (ciprofloxacin and dapsone) and antihypertensive agents (nitrendipine), increase the effect of immunosuppressants (cyclosporine), oral contraceptives (oestrogen) and cholesterol-lowering agents (clofibrate) might promote the formation of gallstones.
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