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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Sep 30, 2024 | 4:52 PM IST

Adelphane Tablet is used to treat high blood pressure (hypertension). It contains Reserpine and Dihydralazine. It works by relaxing and dilating the blood vessels, improving blood flow and lowering blood pressure. In some cases, this medication may cause side effects such as headache, nausea, vomiting, diarrhoea, and loss of appetite. These side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

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Manufacturer/Marketer

Novartis India Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Adelphane Tablet

Adelphane Tablet is indicated in the treatment of high blood pressure (hypertension). High blood pressure is a condition in which the blood exerts increased pressure on the walls of blood vessels.

Adelphane Tablet contains Reserpine and Dihydralazine. It works by relaxing and dilating the blood vessels, improving blood flow and lowering blood pressure.

In some cases, Adelphane Tablet may cause side effects such as headache, nausea, vomiting, diarrhoea, and loss of appetite. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

Do not take Adelphane Tablet if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Keep the doctor informed about your health condition and medications to avoid unpleasant side effects/interactions.

Uses of Adelphane Tablet

Treatment of hypertension (high blood pressure).

Medicinal Benefits

Adelphane Tablet belongs to the class of rauwolfia alkaloids, centrally acting antiadrenergic agents used to treat high blood pressure (hypertension). It contains Reserpine and Dihydralazine. Reserpine works by slowing the nervous system's activity, causing the heartbeat to slow and the blood vessels to relax. Dihydralazine relaxes the muscles in the blood vessels to help them dilate (widen). This lowers blood pressure and allows blood to flow more easily. Together, Adelphane Tablet helps treat high blood pressure.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Adelphane Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Headache
  • Loss of appetite

Drug Warnings

Do not take Adelphane Tablet if you are allergic to any of its components. Inform the doctor if you have/had depression, suicidal thoughts, stomach ulcer, ulcerative colitis, gall stones, liver or kidney problems, stomach problems or slow digestion, heart problems, stroke, or systemic lupus erythematosus (an inflammatory disease). Consult the doctor if you are pregnant or breastfeeding. Let the doctor know if you take other medicines, including supplements or herbal products.

Drug Interactions

Drug-Drug Interactions: Inform the doctor if you are taking sedatives (zolpidem), benzodiazepines (clonazepam, alprazolam), alkylating agents (procarbazine), pain killers (aspirin, acetaminophen/hydrocodone), or lipid-lowering agents (rosuvastatin, atorvastatin).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have depression, ulcerative colitis, bone marrow suppression, heart problems, lupus erythematosus, peripheral oedema, biliary colic, or renal dysfunction. 

Drug-Drug Interactions Checker List

  • ZOLPIDEM
  • CLONAZEPAM
  • ALPRAZOLAM
  • PROCARBAZINE
  • ASPIRIN
  • ACETAMINOPHEN+HYDROCODONE
  • ROSUVASTATIN
  • ATORVASTATIN

Habit Forming

No

Diet & Lifestyle Advise

  • Follow a low-salt and low-fat diet. 
  • Exercise regularly for at least 30 minutes most days.
  • Eat a diet rich in whole grains, vegetables, and fruits.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Manage stress with meditation, yoga, and massage.

Disease/Condition Glossary

High blood pressure (hypertension): It is a condition in which the blood exerts increased pressure on the walls of blood vessels, leading to hypertension. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. Symptoms of high blood pressure include headache, dizziness, nose bleed, changes in vision, chest pain, weakness and dyspnoea (shortness of breath). However, most of the time, there are no signs or symptoms of hypertension.

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Alcohol

Caution

Consuming alcohol along with Adelphane Tablet may have additive effects in lowering blood pressure. Therefore, avoid alcohol consumption during treatment with Adelphane Tablet .

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Pregnancy

Consult your doctor

Consult the doctor if you are pregnant, think you may be pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Limited information is available. Consult the doctor if you are breastfeeding.

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Driving

Caution

Adelphane Tablet may cause dizziness in some cases. Drive or operate heavy machinery only if you are alert.

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Liver

Consult your doctor

Limited information is available. Please consult the doctor if you have liver problems or any concerns regarding this.

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Kidney

Consult your doctor

Limited information is available. Please consult the doctor if you have kidney problems or any concerns regarding this.

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Children

Caution

Adelphane Tablet may not be recommended for children under 18 years of age. However, please consult the doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India.
Other Info - ADE0002

Author Details

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FAQs

Adelphane Tablet is used to treat hypertension (high blood pressure).
Adelphane Tablet improves blood flow by relaxing and widening the blood vessels. Thereby, Adelphane Tablet helps treat high blood pressure.
High blood pressure increases the workload on the arteries and heart. If untreated, it could damage the blood vessels of the heart, brain, and kidney and might result in stroke, heart failure or kidney failure. Hypertension increases the risk of heart attacks. Therefore, anti-hypertensives such as Adelphane Tablet are used to lower the blood pressure to normal; this reduces the risk of developing these disorders.
Please do not stop taking Adelphane Tablet without consulting your doctor, as it may raise your blood pressure. To treat your condition effectively, continue taking Adelphane Tablet for as long as your doctor has prescribed it. Do not hesitate to speak with your doctor if you experience difficulty taking Adelphane Tablet .

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