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Reviewed By Praneetha Akunuri , M.Pharmacy

Adelphane Esidrex Tablet is used to treat high blood pressure (hypertension). It contains Reserpine, Hydrochlorothiazide, and Dihydralazine. It works by widening and relaxing blood vessels, enhancing blood flow, and reducing blood pressure. Additionally, it increases urine production, helping the kidneys eliminate excess water and salt from the body. In some cases, this medication may cause side effects such as headache, nausea, vomiting, diarrhea, and loss of appetite. Most of these side effects of Adelphane Esidrex Tablet may not require medical attention and resolve gradually over time. However, you are advised to consult your doctor if the side effects persist or worsen.

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Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Adelphane Esidrex Tablet

Adelphane Esidrex Tablet is indicated in the treatment of high blood pressure (hypertension). High blood pressure is a condition in which the blood exerts increased pressure on the walls of blood vessels.

Adelphane Esidrex Tablet contains Reserpine, Hydrochlorothiazide, and Dihydralazine. It works by widening and relaxing blood vessels, enhancing blood flow, and reducing blood pressure. Additionally, it increases urine production, helping the kidneys eliminate excess water and salt from the body.

In some cases, Adelphane Esidrex Tablet may cause side effects such as headache, nausea, vomiting, diarrhea, and loss of appetite. Most of these side effects of Adelphane Esidrex Tablet may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

Do not take Adelphane Esidrex Tablet if you are allergic to it or any of its components. Consult the doctor if you are pregnant or breastfeeding. To avoid unpleasant side effects or interactions, keep the doctor informed about your health condition and medications.

Uses of Adelphane Esidrex Tablet

Adelphane Esidrex Tablet is used in the treatment of hypertension (high blood pressure).

Directions for Use

Swallow Adelphane Esidrex Tablet as a whole with a glass of water. Do not crush, break, or chew it.

Medicinal Benefits

Adelphane Esidrex Tablet is a combination medication that contains Reserpine, Hydrochlorothiazide, and Dihydralazine. Reserpine works by slowing the nervous system's activity, causing the heartbeat to slow and the blood vessels to relax. Dihydralazine relaxes the muscles in the blood vessels, can help them dilate (widen), and lowers blood pressure, allowing blood to flow more easily. Hydrochlorothiazide relaxes blood vessels, improves flow, and increases urine production, removing excess fluids. This reduces heart workload, lowers blood pressure, and decreases heart attack and stroke risk. It also relieves swelling and improves daily activity. Together, Adelphane Esidrex Tablet helps treat high blood pressure.

How Adelphane Esidrex Tablet Works

Adelphane Esidrex Tablet contains Reserpine, Hydrochlorothiazide, and Dihydralazine. It works by widening and relaxing blood vessels, enhancing blood flow, and reducing blood pressure. Additionally, it increases urine production, helping the kidneys eliminate excess water and salt from the body.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Adelphane Esidrex Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Headache
  • Loss of appetite

What if I have taken an overdose of Adelphane Esidrex Tablet

Do not exceed the recommended dose of Adelphane Esidrex Tablet , as it may increase the risk of severe side effects like low blood pressure, fainting, rapid heartbeat, and nausea. Seek immediate medical attention if you experience these symptoms or suspect an overdose.

Drug Warnings

Do not take Adelphane Esidrex Tablet if you are allergic to Adelphane Esidrex Tablet or any of its components. Inform your doctor if you have any history of depression, suicidal thoughts, stomach ulcers, gallstones, liver or kidney problems, heart issues, stroke, systemic lupus erythematosus, diabetes, asthma, gout, high cholesterol, or other conditions to ensure safe treatment. Consult the doctor if you are pregnant or breastfeeding. Let the doctor know if you take other medicines, including supplements or herbal products.

Drug-Drug Interactions

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HydrochlorothiazideDofetilide
Critical
HydrochlorothiazideCisapride
Critical

Drug-Drug Interactions

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HydrochlorothiazideDofetilide
Critical
How does the drug interact with Adelphane Esidrex Tablet 10's:
Taking Dofetilide and Adelphane Esidrex Tablet 10's can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Adelphane Esidrex Tablet 10's together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideCisapride
Critical
How does the drug interact with Adelphane Esidrex Tablet 10's:
Taking Cisapride and Adelphane Esidrex Tablet 10's can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Adelphane Esidrex Tablet 10's together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
ReserpineMorphine
Severe
How does the drug interact with Adelphane Esidrex Tablet 10's:
Taking Adelphane Esidrex Tablet 10's with Morphine may increase the blood levels and side effects of morphine.

How to manage the interaction:
Co-administration of Morphine with Adelphane Esidrex Tablet 10's can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
HydrochlorothiazideDroperidol
Severe
How does the drug interact with Adelphane Esidrex Tablet 10's:
Co-administration of Droperidol and Adelphane Esidrex Tablet 10's can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Droperidol and Adelphane Esidrex Tablet 10's together can possibly result in an interaction, but they can be taken if advised by your doctor. However, consult the doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideZiprasidone
Severe
How does the drug interact with Adelphane Esidrex Tablet 10's:
Taking Ziprasidone and Adelphane Esidrex Tablet 10's can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Ziprasidone and Adelphane Esidrex Tablet 10's together is avoided as it can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideDronedarone
Severe
How does the drug interact with Adelphane Esidrex Tablet 10's:
Co-administration of Dronedarone and Adelphane Esidrex Tablet 10's can increase the risk of severe irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dronedarone and Adelphane Esidrex Tablet 10's together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideAminolevulinic acid
Severe
How does the drug interact with Adelphane Esidrex Tablet 10's:
Coadministration of Aminolevulinic acid with Adelphane Esidrex Tablet 10's can make your skin more sensitive to bright lights. This could increase the risk or severity of developing a sunburn.

How to manage the interaction:
Although there is a possible interaction between Aminolevulinic acid and Adelphane Esidrex Tablet 10's, it can be taken if advised by your doctor. Avoid exposure of the eyes and skin to sunlight or bright indoor lights for 48 hours. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideLithium
Severe
How does the drug interact with Adelphane Esidrex Tablet 10's:
Coadministration of Lithium and Adelphane Esidrex Tablet 10's can increase the effects of lithium.

How to manage the interaction:
Taking Lithium and Adelphane Esidrex Tablet 10's together can possibly result in an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like loose stools, vomiting, drowsiness, shaking of hands and legs, thirst, increased urination, lack of coordination, or muscle weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideAmiodarone
Severe
How does the drug interact with Adelphane Esidrex Tablet 10's:
Coadministration of Amiodarone together with Adelphane Esidrex Tablet 10's may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and Adelphane Esidrex Tablet 10's interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, Weakness, tiredness, drowsiness, confusion, painful muscle cramping, dizziness, nausea, or vomiting, get medical attention. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideDolasetron
Severe
How does the drug interact with Adelphane Esidrex Tablet 10's:
Co-administration of Dolasetron and Adelphane Esidrex Tablet 10's can affect the rhythm of your heart which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dolasetron and Adelphane Esidrex Tablet 10's together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like irregular heartbeat, chest tightness, blurred vision, nausea, and seizures, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a low-salt and low-fat diet.
  • Exercise for at least 30 minutes regularly
  • Eat a diet rich in whole grains, vegetables, and fruits.
  • Quit smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Manage stress with meditation, yoga, and massage.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES
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Alcohol

Caution

Avoid consuming alcohol while taking Adelphane Esidrex Tablet , as it may enhance blood pressure-lowering effects and increase the risk of adverse reactions.

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Pregnancy

Consult your doctor

Consult your doctor if you are pregnant or are planning to conceive before taking Adelphane Esidrex Tablet .

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Breast Feeding

Consult your doctor

Limited information is available. Please consult your doctor before taking Adelphane Esidrex Tablet if you are breastfeeding.

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Driving

Caution

Adelphane Esidrex Tablet may cause dizziness. Exercise caution and only drive or operate heavy machinery if you feel alert.

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Liver

Consult your doctor

Limited information is available. If you have liver impairments or diseases, please consult your doctor before taking Adelphane Esidrex Tablet .

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Kidney

Consult your doctor

Limited information is available. If you have kidney impairments or diseases before taking Adelphane Esidrex Tablet .

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Children

Caution

Adelphane Esidrex Tablet may not be recommended for children under 18 years of age. However, please consult the doctor if you have any concerns.

FAQs

Adelphane Esidrex Tablet is used to treat hypertension (high blood pressure).
Adelphane Esidrex Tablet works by widening and relaxing blood vessels, enhancing blood flow, and reducing blood pressure. Additionally, it increases urine production, helping eliminate excess water and salt through the kidneys from the body. Thereby, Adelphane Esidrex Tablet helps treat high blood pressure.
When blood pressure is high, it increases the workload on arteries and the heart. It can damage blood vessels if untreated in the heart, brain, and kidneys, potentially leading to stroke, heart failure, or kidney failure and increasing heart attack risk. Antihypertensives like Adelphane Esidrex Tablet help lower blood pressure, reducing the risk of these disorders.
Do not stop taking Adelphane Esidrex Tablet without consulting your doctor; it may raise your blood pressure. Take it as prescribed to manage your condition effectively. If you experience difficulties, discuss them with your doctor.
The common side effects of Adelphane Esidrex Tablet may include headache, nausea, vomiting, diarrhea, and loss of appetite. Most of these side effects of Adelphane Esidrex Tablet may not require medical attention and resolve gradually over time. However, consult your doctor immediately if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India.
Other Info - ADE0001

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