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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:49 PM IST
Acynac Rb Capsule is used to reduce and relieve pain and inflammation (swelling) associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It may also be indicated in the treatment of pain associated with post-traumatic and post-operative cases. It contains Aceclofenac and Rabeprazole, which works by reducing the production of prostaglandins (chemicals) that cause pain and inflammation. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Aceclofenac has been reported to cause gastric discomfort and acidity. Hence, it is combined with Rabeprazole, which reduces the amount of acid the stomach makes, thus preventing damage to the stomach. Thus, it helps reduce pain with minimal gastric irritation caused due to Aceclofenac alone. In some cases, you may experience side effects such as indigestion, stomach pain, constipation, dizziness, nausea and diarrhoea.
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Manufacturer/Marketer :

Global Medisciences Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Acynac Rb Capsule

Acynac Rb Capsule is used to reduce and relieve pain and inflammation (swelling) associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Acynac Rb Capsule may also be indicated in the treatment of pain associated with post-traumatic and post-operative cases.

Acynac Rb Capsule combines two drugs: Aceclofenac (painkiller) and Rabeprazole (antacid). Aceclofenac works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. By blocking the effect of COX enzymes, fewer prostaglandins are produced. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Aceclofenac has been reported to cause gastric discomfort and acidity. Hence, it is combined with Rabeprazole, a medicine belonging to a group of proton pump inhibitors that reduce the amount of acid the stomach makes, thus preventing damage to the stomach. Thus, the combination helps alleviate pain with minimal gastric irritation caused by Aceclofenac alone.

Take Acynac Rb Capsule as prescribed by your doctor. You are advised to take Acynac Rb Capsule for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience indigestion, stomach pain, constipation, dizziness, nausea and diarrhoea. Most of these side effects of Acynac Rb Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before taking the Acynac Rb Capsule , let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. Inform your doctor if you are suffering from kidney, liver, or heart disease. Acynac Rb Capsule may cause dizziness, so avoid driving or operating machinery unless you are alert. Acynac Rb Capsule is not recommended for use during pregnancy, breastfeeding, or in children. Avoid consuming alcohol along with Acynac Rb Capsule as it could lead to increased dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Acynac Rb Capsule

Treatment of Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis.

Medicinal Benefits

Acynac Rb Capsule is a combination of two drugs: Aceclofenac (painkiller) and Rabeprazole (antacid). Aceclofenac belongs to the class of non-steroidal anti-inflammatory drugs (pain killers) that block the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). Prostaglandins play an important role in controlling pain and inflammation. By blocking the effect of COX enzymes, fewer PGs are produced. Thereby, it helps relieve pain and swelling associated with different types of arthritis, such as osteoarthritis, rheumatoid arthritis and ankylosing spondylitis (pain and stiffness in the backbone). On the other hand, Rabeprazole belongs to proton pump inhibitors (PPIs) that help reduce the excess amount of stomach acid and bile produced. Aceclofenac has been reported to cause gastric discomfort and acidity. Hence, it is combined with Rabeprazole, a medicine that reduces the amount of acid made by the stomach, thus preventing damage to the stomach. Thus, the combination is superior as it helps alleviate pain with minimal gastric irritation caused by Aceclofenac alone. Acynac Rb Capsule is also used to relieve toothache and lower back, ear, and throat pain. 

Side Effects of Acynac Rb Capsule

  • Indigestion

  • Stomach pain

  • Constipation

  • Dizziness

  • Nausea

  • Diarrhoea

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Acynac Rb Capsule if you are allergic to Acynac Rb Capsule , have severe heart failure, suffered bleeding problems (such as bleeding from the stomach or bowels while taking any pain killers) or liver or kidney problems, have suffered bleeding problems and clotting problems. Inform your doctor before taking Acynac Rb Capsule if you have or had disorders of the stomach, blood circulation problems to the brain, asthma, porphyria (a disorder in the formation of red blood pigment), diabetes, high blood pressure, systemic lupus erythematosus (an autoimmune condition that causes joint pain, fever and skin rashes), colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhoea, bowel pain, vomiting and weight loss); if you are recovering from major surgery or if you are elderly. Do not take Acynac Rb Capsule if you are pregnant or breastfeeding unless prescribed. Acynac Rb Capsule contains Aceclofenac which should not be used during the last three months of pregnancy. Acynac Rb Capsule may be excreted in breastmilk. Therefore, avoid breastfeeding and consult a doctor. Acynac Rb Capsule should not be given to children as safety has not been established. Acynac Rb Capsule can cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol with Acynac Rb Capsule as it could lead to increased drowsiness and increase the risk of stomach bleeding. Do not take other NSAIDs for pain relief or Acynac Rb Capsule unless prescribed. Prolonged intake of PPIs or proton pump inhibitors like Rabeprazole may cause brittle bones so intake of Vitamin D and calcium can be additionally given by your doctor while using Acynac Rb Capsule . 

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.

  • Acupuncture, massage and physical therapy may also be helpful.

  • Foods containing flavonoids such as soy, berries, broccoli, grapes and green tea help in reducing inflammation.

  • Include high fibre-containing foods, berries, cherries, leafy green veggies, and black peppers in your meal. These foods are full of antioxidants, calcium, and vitamin B12 that can help cope with the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics that help in the prevention of excess stomach acid production.

  • Avoid intake of acid or heartburn triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, and high-fat and spicy foods.

  • Avoid smoking and alcohol consumption.

Habit Forming

No

How Acynac Rb Capsule Works

Acynac Rb Capsule combines two drugs: Aceclofenac (painkiller) and Rabeprazole (antacid). Aceclofenac works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. By blocking the effect of COX enzymes, fewer prostaglandins are produced. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Aceclofenac has been reported to cause gastric discomfort and acidity. Hence, it is combined with Rabeprazole, a medicine belonging to a group of proton pump inhibitors that reduce the amount of acid the stomach makes, thus preventing damage to the stomach. Thus, the combination helps alleviate pain with minimal gastric irritation caused by Aceclofenac alone.

What if I have taken an overdose of Acynac Rb Capsule

Do not take more than the prescribed dose of Acynac Rb Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Acynac Rb Capsule . Alcohol intake along Acynac Rb Capsule may cause increased drowsiness and drowsiness. It may also increase the risk of stomach bleeding. Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Unsafe

Acynac Rb Capsule is a Category C pregnancy drug and is not recommended for pregnant women, especially in the third trimester as it may cause adverse effects in the baby. However, please consult a doctor if you are pregnant or planning for pregnancy before taking Acynac Rb Capsule .

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Acynac Rb Capsule as it may be excreted in breast milk and cause adverse effects in the baby. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Acynac Rb Capsule may cause drowsiness, dizziness, or abnormal vision. Do not drive or operate heavy machinery if you feel dizzy or drowsy.

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Liver

Caution

Dose adjustment may be needed in patients with severe liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Take Acynac Rb Capsule with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Acynac Rb Capsule if you have severe kidney disease.

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Children

Unsafe

Acynac Rb Capsule is not recommended for children below 18 years of age, as the safety and effectiveness were not established.

Country of origin

India
Other Info - ACY0020

Author Details

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FAQs

Acynac Rb Capsule is used to reduce and relieve pain and inflammation (swelling) associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It may also be indicated in the treatment of pain associated with post-traumatic and post-operative cases.
Acynac Rb Capsule contains Aceclofenac and Rabeprazole. Aceclofenac is a pain killer called NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) which works by blocking the effect of chemical messengers (prostaglandin), thereby helping in reducing pain, and inflammation. Rabeprazole works by blocking the action of an enzyme called a proton pump, which is responsible for the production of stomach acid. Thus, the combination used for pain relief, decrease stiffness in joints and reduces the release of excess stomach acid caused by aceclofenac.
Acynac Rb Capsule is not recommended for asthma patients as it may worsen the condition. Therefore, please inform your doctor if you have asthma or a history of asthma due to the use of aspirin or any other non-steroidal drugs.
You are not recommended to take Acynac Rb Capsule with warfarin as co-administration of these two medicines may increase the risk of bleeding more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.
Aceclofenac in Acynac Rb Capsule may increase the risk of heart problems such as heart attack, especially when used in high doses or for prolonged duration and in patients who are smokers, have high blood pressure, diabetes or high cholesterol. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking Acynac Rb Capsule . However, taking Acynac Rb Capsule in the dose and for the duration, as prescribed by your doctor, is recommended.
Acynac Rb Capsule may impair fertility in females and make it more difficult to conceive. Therefore, if you are pregnant, planning for pregnancy or have difficulties conceiving, please consult your doctor before taking Acynac Rb Capsule .
Do not take Acynac Rb Capsule for longer durations as it might increase the risk of heart problems, stomach bleeding and might increase the risk of fractures of the hip, spine, and wrist. Do not exceed the dose and duration of treatment as prescribed by the doctor.
Acynac Rb Capsule is a combination medicine containing Aceclofenac (painkiller) and Rabeprazole (antacid). It is used to treat osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
Do not discontinue Acynac Rb Capsule without consulting your doctor. To treat your condition effectively, keep taking Acynac Rb Capsule for the prescribed duration.
Nausea and vomiting could be side effects of Acynac Rb Capsule . Drink enough fluids by taking frequent sips and eat small, frequent meals. If the condition persists or worsens, consult the doctor.
Store Acynac Rb Capsule at room temperature, in a dry place. Keep it out of sight and reach of children.
Acynac Rb Capsule may cause side effects like indigestion, stomach pain, constipation, dizziness, nausea and diarrhoea. Most of these side effects of Acynac Rb Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Acynac Rb Capsule may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol with Acynac Rb Capsule as it could lead to increased drowsiness.
Acynac Rb Capsule can be taken with vitamin B-complex if advised by the doctor. Talk to the doctor if you have any concerns.

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