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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 22, 2024 | 7:36 PM IST
Actoid 25 Capsule is used to treat psoriasis. It contains Acitretin, which slows down the progression of the disease. It reduces the speed of skin cell growth and gradually clears the affected skin. It helps reduce the redness, scaling, and thickness of psoriasis rashes. It may cause side effects such as dry lips, peeling of the skin, scaling and thinning of healthy skin, reddening of the skin, itching and burning sensation on the skin.
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Composition

ACITRETIN-25MG

Manufacturer/Marketer

Intas Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Actoid 25 Capsule

Actoid 25 Capsule is used to treat psoriasis. Psoriasis is an autoimmune (immune system attacks healthy cells) skin disorder in which the skin becomes scaly, swollen, and itchy. It mostly affects the knee, elbows, scalp, and trunk. It is a lifelong condition, and treatment is given to remove affected skin cells and avoid flare-ups of the disease.

Actoid 25 Capsule contains ‘Acitretin’, which belongs to the class of retinoids derived from vitamin A. It has anti-inflammatory and antiproliferative (decreases skin cell multiplication) properties. It works by slowing down the progression of the disease. It reduces the speed of skin cell growth and gradually clears the affected skin. It helps reduce the redness, scaling, and thickness of psoriasis rashes.

Actoid 25 Capsule may cause side-effects such as dry lips, peeling of the skin, especially the palms of the hands and soles of the feet, nose bleed, scaling and thinning of healthy skin, reddening of the skin, itching, burning sensation on the skin, sticky skin, hair loss, swelling and pain in the area around your nails, fragile nails, inflammation of the eye (conjunctivitis), increased thirst, and feeling cold. These side effects usually go away after discontinuing the treatment. However, if any of these side effects persist or worsen, inform your doctor immediately.

Do not take Actoid 25 Capsule if you are allergic to Acitretin or any other ingredients present in it. Actoid 25 Capsule should not be used in patients with liver or kidney failure or high cholesterol and who are taking other medicines containing retinoids or supplements containing vitamin A. Actoid 25 Capsule should not be used in pregnant and breastfeeding women. Actoid 25 Capsule should be used with caution in children as it may affect growth and bone development. Actoid 25 Capsule may require dose adjustments when used in older people. Do not take alcohol, as it may increase the risk of side effects. Actoid 25 Capsule may cause vision problems, especially in the dark, so do not drive or operate heavy machinery if you notice any vision problems.

Uses of Actoid 25 Capsule

Treatment of Psoriasis

Medicinal Benefits

Actoid 25 Capsule contains ‘Acitretin’, which belongs to the class ‘retinoids’. Retinoids are derived from vitamin A (retinol) and have anti-inflammatory and antiproliferative (reduces rapid skin cell division) action. Actoid 25 Capsule works by slowing down the progression of the diseases. Actoid 25 Capsule is used when the skin condition doesn’t improve with other conventional therapies. It can treat severe or extensive skin problems where the skin has become thick and scaly, such as psoriasis. It can be long-term maintenance therapy for psoriasis patients. It can also be used in the treatment of other skin conditions such as ichthyosis (genetic skin disorder), pityriasis (skin rashes that appear as large spots on the chest, abdomen, or back), and lichen planus (itchy, non-infectious rashes on arms and legs).

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Actoid 25 Capsule

  • Dry lips

  • Peeling of the skin, especially the palms of the hands and soles of the feet

  • Nose bleed

  • Scaling and thinning of healthy skin

  • Reddening of the skin

  • Itching

  • Burning sensation on the skin

  • Sticky skin

  • Hair loss

  • Swelling and pain in the area around your nails

  • Fragile nails

  • Inflammation of the eye (conjunctivitis)

  • Increased thirst

  • Feeling cold

Drug Warnings

Actoid 25 Capsule should not be used in pregnant and breastfeeding women. So, the doctor may advise you to take a pregnancy test before using Actoid 25 Capsule . You should also take effective and reliable contraception (such as an intrauterine device, contraceptive implant, or contraceptive pill and condom) during the treatment and after three years of discontinuing the treatment. You should take reliable contraception even if your periods are not regular or not sexually active unless your doctor decides that this is unnecessary. You should not donate blood during the treatment and after three years of discontinuing the treatment. Actoid 25 Capsule should be used in caution in patients with diabetes as it can alter blood glucose levels. Actoid 25 Capsule may cause vision problems, especially in the night-time. So, inform your doctor if you notice vision problems. Do not wear contact lenses during the treatment as the Actoid 25 Capsule may cause dry eyes. Actoid 25 Capsule may increase skin sensitivity, so avoid going in strong sunlight and using a sunbed. Actoid 25 Capsule may affect your mood, so inform your doctor if you have mental health problems like depression. Also, inform your doctor if you notice drastic mood changes while using Actoid 25 Capsule .

Drug Interactions

Drug-Drug Interactions: Actoid 25 Capsule should not be used in patients taking other retinoids or supplements containing vitamin A. Actoid 25 Capsule may interact with an antibiotic (tetracycline) and cause increased pressure in the brain. It may interact with a medicine used to treat cancer, psoriasis, or rheumatic diseases (methotrexate) and cause liver damage. It may decrease the efficacy of an antiepileptic drug (phenytoin). It may also interact with a mini-pill (a type of birth control pill with low doses of progesterone).

Drug-Food Interactions: Do not consume alcohol while using Actoid 25 Capsule as it may increase the risk of side effects.

Drug-Disease Interactions: Actoid 25 Capsule should be used with caution in patients with liver or kidney failure, high cholesterol, overweight, alcoholic abuse, diabetes, and mental health problems.

Drug-Drug Interactions Checker List

  • TETRACYCLINE
  • METHOTREXATE
  • PHENYTOIN

Habit Forming

No

Diet & Lifestyle Advise

  • Use mild soap while taking baths and prefer warm baths.
  • Do not scratch or pick your skin to avoid infecting the affected area.
  • Avoid harsh products on your skin.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Limit intake of food that might trigger allergies such as dairy products, soy, eggs, and nuts.
  • Avoid consuming foods with excess sugar, as it may flare up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats, and fish in your diet.
  • Avoid getting in contact with harsh soaps, detergents, and rough fabrics. 

Special Advise

  • Growth and bone development should be regularly monitored if the Actoid 25 Capsule is given to children.

  • Patients with diabetes are advised to monitor blood glucose levels while using this medicine regularly.

  • Patients with high cholesterol should regularly monitor fat levels in the blood while using this medicine.

  • Your doctor may also check liver function before, during, and after three weeks of discontinuing Actoid 25 Capsule , as this medicine may affect liver function.

  • If Actoid 25 Capsule is prescribed for the long-term, your doctor may perform an x-ray of certain bones once a year, as this medicine may affect bone development.

  • Actoid 25 Capsule may cause birth defects, so women planning for pregnancy are advised to the regular pregnancy test and should not become pregnant for the next three years after using Actoid 25 Capsule .

Disease/Condition Glossary

Psoriasis: Psoriasis is an autoimmune skin disease characterized by red, itchy, and scaly rashes. It occurs when the immune system mistakenly attacks healthy skin cells. In this condition, skin cells grow and build up rapidly, resulting in scaly rashes, mostly on the knees, elbows, scalp, and trunk. Stress and cold can act as triggers for this disease. It is a chronic disease and doesn’t have a permanent cure. Treatment is given to control the disease and prevent flare-ups.

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Alcohol

Unsafe

Actoid 25 Capsule may interact with alcohol and increase the risk of side-effects. So, it is not recommended to take alcohol, especially women of childbearing potential during the treatment and at least 2 months after completing the treatment.

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Pregnancy

Caution

Actoid 25 Capsule should not be used in pregnant women as it may cause harmful effects to the unborn baby or fetus. Consult your doctor for further advice.

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Breast Feeding

Caution

Actoid 25 Capsule should not be given to breastfeeding mothers as it may pass into breast milk and harm the nursing baby. Consult your doctor for further advice.

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Driving

Unsafe

Actoid 25 Capsule may cause vision problems suddenly, especially in the dark. So, do not drive or operate heavy machinery if you notice any vision problems, especially at night.

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Liver

Caution

Actoid 25 Capsule should not be used in patients with severe liver failure as Actoid 25 Capsule may cause liver damage. In mild to moderate liver diseases, the dose may have to be adjusted by your doctor.

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Kidney

Caution

Actoid 25 Capsule should not be used in patients with severe kidney failure. In mild to moderate kidney diseases, the dose may have to be adjusted by your doctor.

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Children

Caution

Actoid 25 Capsule should be used in children only if clinically needed as it may affect growth and bone development. The dose may have to be adjusted by your doctor.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ACT0434

Author Details

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FAQs

Actoid 25 Capsule is used to treat psoriasis, an autoimmune (immune system attacks healthy cells) skin disorder in which the skin becomes scaly, swollen, and itchy.
Actoid 25 Capsule contains 'Acitretin', which belongs to the class of 'retinoids' and is used to treat severe psoriasis. It has anti-inflammatory action and reduces the rashes' redness, scaling, and thickness. It also has antiproliferative properties and slows down the disease's progression by reducing the speed of skin cell growth.
Actoid 25 Capsule may cause vision problems suddenly, especially in the dark. So, inform your doctor immediately if you experience vision problems. Also, refrain from activities such as driving or operating heavy machinery if you have a problem with your vision.
You should not donate blood during the treatment with Actoid 25 Capsule and within three years of discontinuing the treatment. An unborn baby may get harmed if a pregnant woman receives your donated blood.
Actoid 25 Capsule may not affect your immune system. It is not an immunosuppressant. It controls psoriasis by slowing down the progression of the disease.
Actoid 25 Capsule may affect blood glucose levels and should be used with caution in patients with diabetes. You may have to regularly monitor blood glucose levels while using this medicine.
Actoid 25 Capsule may cause side-effects such as dry lips, peeling of the skin, especially the palms of the hands and soles of the feet, nose bleed, scaling and thinning of healthy skin, reddening of the skin, itching, burning sensation on the skin, sticky skin, hair loss, swelling and pain in the area around your nails, fragile nails, inflammation of the eye (conjunctivitis), increased thirst, and feeling cold. If any of these side effects persist or worsen, inform your doctor immediately.
Actoid 25 Capsule should not be used in pregnant women as it may cause harmful effects to the unborn baby or foetus. Consult your doctor for further advice.
No, Actoid 25 Capsule is not an immunosuppressant. It belongs to the class of retinoids used to treat psoriasis.
Drinking alcohol with Actoid 25 Capsule may increase the risk of side effects. So, it is not recommended to take alcohol, especially women of childbearing potential during the treatment and at least 2 months after completing the treatment.
You may notice an improvement in 4-6 weeks of using Actoid 25 Capsule . However, it might take 3-4 months to notice the full benefits.
Actoid 25 Capsule may cause foetal harm; so, do not take Actoid 25 Capsule if you are pregnant or plan to become pregnant within the next 3 years. Actoid 25 Capsule may cause liver damage. Inform the doctor if you have or have ever had liver disease. Consult your doctor immediately if you experience symptoms of liver damage such as nausea, vomiting, pain in the upper right part of the stomach, loss of appetite, and yellowing of the skin or eyes, or dark urine.
Actoid 25 Capsule may not affect semen. However, a small amount of Actoid 25 Capsule is present in the semen of male patients who take this medication. Though it is not known if this affects the foetus, talk to your doctor about the risks of taking Actoid 25 Capsule if your partner is pregnant or plans to become pregnant.
Take Actoid 25 Capsule with the main meal. It should be swallowed as a whole with water; do not crush or chew it.
Avoid becoming pregnant and alcohol consumption during treatment with Actoid 25 Capsule as it might affect the foetus. Do not donate blood while taking Actoid 25 Capsule and for 3 years after treatment. Actoid 25 Capsule may cause blurred vision; so, do not drive or operate machinery unless you are alert. Actoid 25 Capsule may make your skin sensitive to sunlight; therefore, avoid prolonged exposure to sunlight.

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