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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Actispas 80mg/250mg Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. It contains Drotaverine and Mefenamic acid, which works by reducing calcium reuptake by the cells, thereby correcting the body's calcium levels and relieving contractions associated with smooth muscles. Also, it blocks the effect of chemical messengers that cause pain and inflammation. In some cases, it may cause common side effects such as gastrointestinal disturbances, feeling thirsty, nausea, vomiting, diarrhoea, dry mouth, rashes and itching. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

TNT Lifesciences

Consume Type :

ORAL

Return Policy :

Not Returnable

About Actispas 80mg/250mg Tablet

Actispas 80mg/250mg Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.

Actispas 80mg/250mg Tablet is a combination of two drugs: Drotaverine (anti-spasmodic) and Mefenamic acid (NSAID). Drotaverine works by reducing calcium reuptake by the cells, thereby correcting the body's calcium levels and relieving contractions associated with smooth muscles. Mefenamic acid works by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Together, Actispas 80mg/250mg Tablet helps in relieving pain.

You are advised to take Actispas 80mg/250mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as gastrointestinal disturbances, feeling thirsty, nausea, vomiting, diarrhoea, dry mouth, rashes and itching. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you have/had asthma, peptic ulcers, porphyria, or bleeding problems. Consult your doctor if you are pregnant or breastfeeding. Actispas 80mg/250mg Tablet may cause dizziness, so drive with caution. Actispas 80mg/250mg Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Actispas 80mg/250mg Tablet

Treatment of Pain relief

Directions for Use

Take Actispas 80mg/250mg Tablet with food to prevent stomach upset. Swallow Actispas 80mg/250mg Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Actispas 80mg/250mg Tablet is a combination of two drugs: Drotaverine and Mefenamic acid. Actispas 80mg/250mg Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. Drotaverine is an antispasmodic that reduces calcium reuptake by the cells, thereby correcting the calcium levels in the body and relieving contractions associated with smooth muscles. Mefenamic acid is an NSAID which works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzymes' effect, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Actispas 80mg/250mg Tablet helps in relieving pain.

How Actispas 80mg/250mg Tablet Works

Actispas 80mg/250mg Tablet is a combination of two drugs: Drotaverine (anti-spasmodic) and Mefenamic acid (NSAID). Drotaverine works by reducing calcium reuptake by the cells, thereby correcting the body's calcium levels and relieving contractions associated with smooth muscles. Mefenamic acid works by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Together, Actispas 80mg/250mg Tablet helps in relieving pain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Actispas 80mg/250mg Tablet

  • Gastrointestinal disturbances
  • Feeling thirsty
  • Nausea
  • Vomiting
  • Diarrhoea
  • Dry mouth
  • Rashes
  • Itching

What if I have taken an overdose of Actispas 80mg/250mg Tablet

Do not take more than the prescribed dose of Actispas 80mg/250mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Actispas 80mg/250mg Tablet if you are allergic to any of its contents. Inform your doctor if you have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any painkillers. If you have had any recent heart surgery, do not take Actispas 80mg/250mg Tablet unless prescribed by the doctor, as Actispas 80mg/250mg Tablet may increase the risk of heart attack or stroke. Inform your doctor if you have/had asthma, peptic ulcers, porphyria, bleeding problems, liver or kidney impairment. Consult your doctor if you are pregnant or breastfeeding. Actispas 80mg/250mg Tablet may cause dizziness, so drive only if you are alert. Actispas 80mg/250mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol as it could lead to increased drowsiness and may increase the risk of stomach bleeding. Stop taking Actispas 80mg/250mg Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Actispas 80mg/250mg Tablet unless prescribed.

Drug-Drug Interactions

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Mefenamic acidKetorolac
Critical
Mefenamic acidMeloxicam
Critical

Drug-Drug Interactions

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Mefenamic acidKetorolac
Critical
How does the drug interact with Actispas 80mg/250mg Tablet:
Coadministration of Actispas 80mg/250mg Tablet with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Actispas 80mg/250mg Tablet with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidMeloxicam
Critical
How does the drug interact with Actispas 80mg/250mg Tablet:
Co-administration of Actispas 80mg/250mg Tablet with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Actispas 80mg/250mg Tablet with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Mefenamic acidTenofovir disoproxil
Severe
How does the drug interact with Actispas 80mg/250mg Tablet:
Coadministration of Actispas 80mg/250mg Tablet with Tenofovir disoproxil can show additive effect and increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Actispas 80mg/250mg Tablet with Tenofovir Disoproxil together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, red or black tarry stools, vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidApixaban
Severe
How does the drug interact with Actispas 80mg/250mg Tablet:
Actispas 80mg/250mg Tablet and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Actispas 80mg/250mg Tablet and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without first consulting your doctor, never stop taking any medications.
Mefenamic acidIbrutinib
Severe
How does the drug interact with Actispas 80mg/250mg Tablet:
Co-administration of Actispas 80mg/250mg Tablet with Ibrutinib can increase the risk or severity of bleeding, leading to serious blood loss.

How to manage the interaction:
Taking Actispas 80mg/250mg Tablet with Ibrutinib together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any symptoms of unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidCabozantinib
Severe
How does the drug interact with Actispas 80mg/250mg Tablet:
Using cabozantinib together with Actispas 80mg/250mg Tablet may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Actispas 80mg/250mg Tablet and Cabozantinib, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms like blood clotting problems, excessive bleeding, or severe headaches, it's best to contact a doctor right away. They can help address any complications and provide the necessary support. Do not stop using any medications without talking to a doctor.
Mefenamic acidBaricitinib
Severe
How does the drug interact with Actispas 80mg/250mg Tablet:
Using Actispas 80mg/250mg Tablet and baricitinib together may increase the risk of gastrointestinal perforation (a serious health condition where a hole develops through the stomach or intestine).

How to manage the interaction:
Co-administration of Actispas 80mg/250mg Tablet with Baricitinib can result in an interaction, but it can be taken if your doctor has advised it. If you notice any signs like severe stomach pain, fever, or vomiting, consult a doctor. Do not stop using any medications without talking to a doctor.
Mefenamic acidDalteparin
Severe
How does the drug interact with Actispas 80mg/250mg Tablet:
Combining Actispas 80mg/250mg Tablet with Dalteparin can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although taking Dalteparin and Actispas 80mg/250mg Tablet together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any signs like bleeding, bruising, swelling, vomiting, headache, dizziness, weakness, or blood in your urine or stool, make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
Mefenamic acidEnoxaparin
Severe
How does the drug interact with Actispas 80mg/250mg Tablet:
Combining Actispas 80mg/250mg Tablet with Enoxaparin can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although there is a possible interaction between Actispas 80mg/250mg Tablet and Enoxaparin, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like bleeding, bruising, swelling, vomiting, headache, dizziness, weakness, or blood in your urine or stool, make sure to contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidIndometacin
Severe
How does the drug interact with Actispas 80mg/250mg Tablet:
The combined use of Indometacin and Actispas 80mg/250mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Indometacin with Actispas 80mg/250mg Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

Actispas 80mg/250mg Tablet Substitute

Substitutes safety advice
  • Drotin-M Tablet 10's

    21.06per tablet
  • Drotikind M Tablet 10's

    10.17per tablet
  • DVN Plus Tablet 10's

    18.68per tablet
  • Doverin M Tablet 10's

    12.69per tablet
  • Drofem Tablet 10's

    by AYUR

    7.07per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Actispas 80mg/250mg Tablet as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Actispas 80mg/250mg Tablet if you are breastfeeding. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Actispas 80mg/250mg Tablet may cause drowsiness. Drive or operate machinery only if you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Unsafe

Actispas 80mg/250mg Tablet should not be given to children as the safety and effectiveness were not established.

FAQs

Actispas 80mg/250mg Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery.
Actispas 80mg/250mg Tablet contains Drotaverine and Mefenamic acid. Drotaverine works by relieving contractions associated with smooth muscles of the abdomen. Mefenamic acid works by blocking the action of certain chemical messengers that cause pain.
Diarrhoea might be a side-effect of Actispas 80mg/250mg Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in your stools.
Dry mouth could be a side-effect of Actispas 80mg/250mg Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Do not take Actispas 80mg/250mg Tablet for longer durations as it might increase the risk of heart problems and stomach bleeding. Take Actispas 80mg/250mg Tablet only for as long as your doctor has prescribed it.
Actispas 80mg/250mg Tablet is generally prescribed for short durations and can be discontinued after pain relief. However, you are advised to continue taking Actispas 80mg/250mg Tablet for as long as your doctor has prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Actispas 80mg/250mg Tablet.
Actispas 80mg/250mg Tablet is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take Actispas 80mg/250mg Tablet only as prescribed, and do not overdose.
Actispas 80mg/250mg Tablet may cause dizziness, so drive with caution and only if you are alert. Avoid consuming alcohol as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. Stop taking Actispas 80mg/250mg Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools.
No, do not take Actispas 80mg/250mg Tablet on an empty stomach. Take it with food to prevent stomach upset.
Actispas 80mg/250mg Tablet usually starts working within an hour. However, this might vary individually based on the physical condition.
The doctor will determine the daily dose of Actispas 80mg/250mg Tablet based on your condition. Please consult the doctor if you have any concerns.
Actispas 80mg/250mg Tablet is a combination medicine containing Drotaverine (anti-spasmodic) and Mefenamic acid (NSAID). It is used to relieve abdominal pain associated with various conditions.
Yes, Actispas 80mg/250mg Tablet is safe if taken in the dose and duration prescribed by the doctor.
Yes, Actispas 80mg/250mg Tablet may cause nausea and vomiting as a side effect. If you have nausea and vomiting, get fresh air, take sips of water regularly, and eat smaller, frequent meals. Consult the doctor if the condition persists or worsens.
No, do not take a higher than the recommended dose of Actispas 80mg/250mg Tablet as it may cause overdose. If you suspect you have taken an overdose, please consult a doctor immediately.
Store Actispas 80mg/250mg Tablet at room temperature, in a dry place. Keep it out of sight and reach of children.
Yes, Actispas 80mg/250mg Tablet can be taken with food. Taking Actispas 80mg/250mg Tablet with food helps prevent stomach upset.
Common side effects of Actispas 80mg/250mg Tablet are gastrointestinal disturbances, feeling thirsty, nausea, vomiting, diarrhoea, dry mouth, rashes and itching. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Actispas 80mg/250mg Tablet can be used during pregnancy or breastfeeding if advised by the doctor. The doctor will prescribe Actispas 80mg/250mg Tablet only if the benefits outweigh the risks.
Do not take Actispas 80mg/250mg Tablet for longer durations as it might increase the risk of heart problems and stomach bleeding. Take Actispas 80mg/250mg Tablet only for as long as your doctor has prescribed it.
If you miss a dose of Actispas 80mg/250mg Tablet, take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

Manufacturer/Marketer address

Symbiosis Pharma Pvt. Ltd., Suketi Road, Kala Amb - 173030 (Hp)
Other Info - AC35171

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