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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 2:48 PM IST

Acrogyl DF 400mg/500mg Tablet is used to treat infections caused by bacteria and parasites (amoeba). It contains Metronidazole and Diloxanide which work by killing the infection-causing bacteria and amoeba. This medicine may sometimes cause side effects such as nausea, vomiting, upset stomach, loss of appetite, dry mouth and metallic taste. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Prescription drug

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Manufacturer/Marketer :

Acron Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

About Acrogyl DF 400mg/500mg Tablet

Acrogyl DF 400mg/500mg Tablet belongs to a group of medicines known as antibiotics used to treat various infections caused by bacteria and parasites (amoeba). It is prescribed for the treatment of diarrhea caused by microorganisms Clostridium difficile, Entamoeba histolytica and Giardia lamblia. Additionally, it also treats vaginal and other bacterial infections. Infections caused by amoeba usually happen due to drinking contaminated water or eating food that contains contaminated water. Diarrhea is defined as loose, watery stools or frequent movement of the bowel.

Acrogyl DF 400mg/500mg Tablet contains two medicines namely: Metronidazole and Diloxanide. Acrogyl DF 400mg/500mg Tablet contains Metronidazole which is an antibiotic , it treats the infection by damaging the DNA of the organism and does killing the bacteria. Diloxanide is an amoebicide. It works inside the large intestine to kill the infection causing amoeba (parasites). Altogether Acrogyl DF 400mg/500mg Tablet kills the bacteria and parasites. Acrogyl DF 400mg/500mg Tablet does not treat a viral infection like flu or a common cold.

Take Acrogyl DF 400mg/500mg Tablet as prescribed by your doctor. You are advised to take Acrogyl DF 400mg/500mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. Some common side effects of Acrogyl DF 400mg/500mg Tablet are nausea, vomiting, upset stomach, loss of appetite, dry mouth and metallic taste. If these effects appear and are bothersome, call your doctor or pharmacist.

Use of Acrogyl DF 400mg/500mg Tablet is contraindicated in the patient suffering from central nervous system (CNS) diseases like seizures (fits). Acrogyl DF 400mg/500mg Tablet should not be used during pregnancy, especially during the first trimester. So, let your doctor know if you are pregnant or planning to get pregnant. You should not breastfeed while taking Acrogyl DF 400mg/500mg Tablet as it passes into the breastmilk, and can affect the baby. Do not drive or operate heavy machinery after taking Acrogyl DF 400mg/500mg Tablet as it may cause dizziness, drowsiness and make you less alert.

Uses of Acrogyl DF 400mg/500mg Tablet

Acrogyl DF 400mg/500mg Tablet is used in the treatment of Bacterial Infections, Diahorrea due to Entamoeba histolytica, Giardia lamblia or Clostridium difficile, Vaginal bacterial infections, Dental infections, Post-surgery infections, Skin bacterial infections.

Medicinal Benefits

Acrogyl DF 400mg/500mg Tablet is a broad-spectrum antibiotic that is effective against a wide range of gram-positive and gram-negative bacteria. kills the harmful bacteria and amoeba (Entamoeba histolytica, Giardia lamblia, Clostridium difficile) causing diarrhoea. Acrogyl DF 400mg/500mg Tablet contains Metronidazole which is an antibiotic , it treats the infection by damaging the DNA of the organism and does killing the bacteria. Diloxanide is an amoebicide. It works inside the large intestine to kill the infection causing amoeba (parasites). Altogether Acrogyl DF 400mg/500mg Tablet kills the bacteria and parasites. Acrogyl DF 400mg/500mg Tablet does not treat a viral infection like flu or a common cold.

Side Effects of Acrogyl DF 400mg/500mg Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Upset stomach
  • Loss of appetite
  • Constipation
  • Headache
  • Dizziness
  • Skin rash
  • Dry mouth
  • Sharp, unpleasant metallic taste

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Syrup/suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

You should immediately report to the doctor in case you have symptoms of dehydration like dehydration dry mouth, excessive thirst, wrinkled skin, little or no urination, dizziness and lightheadedness. In some cases, prolonged intake of Acrogyl DF 400mg/500mg Tablet has been associated with leukopenia (low count of white blood cells). Intake of probiotics, prebiotics and plenty of fluids is recommended if you are suffering from dysentery and diarrhea. If you are feeling sick or vomiting, then it is advised to eat simple foods or avoid spicy foods. If a person experiences skin rash or itching after taking Acrogyl DF 400mg/500mg Tablet then they should consult with their doctor.

Therapeutic Class

ANTIBIOTICS

Drug-Drug Interactions

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MetronidazoleEthanol
Critical
MetronidazoleDisulfiram
Critical

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • If you have diarrhea try to drink appropriate amounts of fluids to avoid dehydration.
  • If you have minor diarrhea (less than four stools daily) drinking caffeine-free soft drinks, juices or sport rehydration drinks can be sufficient.
  • If the diarrhoea is more severe, specially formulated rehydration drinks should be taken. Consult your doctor immediately.

Habit Forming

No

How Acrogyl DF 400mg/500mg Tablet Works

Acrogyl DF 400mg/500mg Tablet contains two medicines namely: Metronidazole and Diloxanide. Acrogyl DF 400mg/500mg Tablet contains Metronidazole which is an antibiotic , it treats the infection by damaging the DNA of the organism and does killing the bacteria. Diloxanide is an amoebicide. It works inside the large intestine to kill the infection causing amoeba (parasites). Altogether Acrogyl DF 400mg/500mg Tablet kills the bacteria and parasites. Acrogyl DF 400mg/500mg Tablet does not treat a viral infection like flu or a common cold.

What if I have taken an overdose of Acrogyl DF 400mg/500mg Tablet

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Acrogyl DF 400mg/500mg Tablet to avoid unpleasant side-effects.

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Pregnancy

Unsafe

Acrogyl DF 400mg/500mg Tablet should not be used during pregnancy, especially during the first trimester.

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Breast Feeding

Caution

Take Acrogyl DF 400mg/500mg Tablet only when prescribed, it is known to pass on in a limited quantity via breast milk to the child.

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Driving

Caution

Acrogyl DF 400mg/500mg Tablet may affect driving as it causes dizziness, so it is advised to avoid driving.

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Liver

Caution

Acrogyl DF 400mg/500mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Acrogyl DF 400mg/500mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Caution

Dose to be adjusted and recommended by a child specialist only.

Country of origin

India
Other Info - AC37624

Author Details

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FAQs

Acrogyl DF 400mg/500mg Tablet is used to treat infections caused by bacteria and parasites (amoeba). It is prescribed for the treatment of diarrhoea caused by Clostridium difficile, Entamoeba histolytica and Giardia lamblia. Additionally, it also treats vaginal infections.
Acrogyl DF 400mg/500mg Tablet is an antibiotic medication so it is advised to complete the full course even if you start to feel better to prevent the return of the infection.
Yes, it could be due to jaundice as in rare cases Acrogyl DF 400mg/500mg Tablet can lead to it. Please consult your doctor immediately if the yellowing of the skin persists and does not subside.
You should complete the full course of Acrogyl DF 400mg/500mg Tablet as prescribed by your doctor. After completing the full course of Acrogyl DF 400mg/500mg Tablet will work. You must take Acrogyl DF 400mg/500mg Tablet at the right dose, right times and for the right numbers of days.
Acrogyl DF 400mg/500mg Tablet is an antibacterial medicine that acts only against bacterial infections and not viral infections like common cold and flu. You should not take Acrogyl DF 400mg/500mg Tablet without prior consulting your doctor. Self-medication is dangerous and can lower the efficacy of Acrogyl DF 400mg/500mg Tablet, leading to antibiotic resistance.
If you miss a dose of Acrogyl DF 400mg/500mg Tablet, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.
The side effects of Acrogyl DF 400mg/500mg Tablet include stomach upset, nausea, vomiting, loss of appetite, dry mouth and metallic taste. Consult the doctor if any of these side effects persist or worsen.

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