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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST
Acivir IV Injection is an antiviral medicine used in the treatment of herpes simplex and varicella-zoster (shingles) infections. This medicine contains aciclovir which works by inhibiting the herpes simplex virus type 1 (HSV-1), 2 (HSV-2), and varicella-zoster virus (VZV), thereby preventing the spread of the infection. Common side effects include nausea, vomiting, loss of appetite, itching, hive-like rash, swelling, and injection site reactions.
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Prescription drug

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Composition

ACICLOVIR-25MG

Manufacturer/Marketer

Cipla Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Acivir IV Injection

Acivir IV Injection belongs to the class of 'antivirals' that treats herpes simplex (herpes simplex virus/HSV-1 and HSV-2) infections and varicella-zoster (shingles) infections. Herpes simplex infection, commonly known as herpes, is a viral infection that causes contagious sores, often around the mouth or genitals. Shingles is a viral infection with painful rash or blisters on the skin.

Acivir IV Injection is composed of Aciclovir, which works by killing and stopping the growth of herpes simplex virus type 1 (HSV-1), 2 (HSV-2), and varicella-zoster virus (VZV).

Acivir IV Injection will be administered by a healthcare professional; do not self-administer. Common side effects of Acivir IV Injection include nausea, vomiting, loss of appetite, itching, hive-like rash, sensitivity to light (photosensitivity), swelling, redness and tenderness at the injection site. These side effects may not occur in every patient using this medication and gradually resolve over time. If the side effects persist longer or worsen, please seek a doctor's advice.

Let your doctor know if you are allergic to any medications. Inform your doctor if you have a weakened immune system, breathing problems, an electrolyte imbalance, and liver or kidney diseases before starting Acivir IV Injection. Pregnant and breastfeeding women should consult their doctor before starting Acivir IV Injection. It is advised to avoid alcohol consumption while being treated with Acivir IV Injection to enable your body to fight off infections and reduce the worsening of side effects. Acivir IV Injection is given to children only when advised by a doctor based on the child's age and weight.

Uses of Acivir IV Injection

Treatment of Herpes simplex and varicella-zoster (shingles) infections

Medicinal Benefits

Acivir IV Injection treats viral infections caused by the herpes simplex and varicella-zoster viruses. It consists of Aciclovir, an antiviral drug. It works by killing and stopping the growth of the virus. Acivir IV Injection effectively treats herpes simplex encephalitis (brain inflammation by herpes simplex virus) and neonatal herpes simplex virus infection. Acivir IV Injection is also useful in preventing the reactivation of the cytomegalovirus infection in seropositive (showing a positive result of a blood test for a particular antibody) patients following bone marrow transplantation.

Directions for Use

Acivir IV Injection will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Acivir IV Injection

  • Nausea
  • Vomiting
  • Loss of appetite
  • Itching
  • Hive-like rash
  • Sensitivity to light (photosensitivity)
  • Swelling, redness and tenderness at the injection site

Drug Warnings

Inform your doctor if you are using prescription, non-prescription drugs, and herbal products before starting Acivir IV Injection. Let your doctor know if you are allergic to any of the components in Acivir IV Injection. Keep your doctor informed of your medical history before starting Acivir IV Injection. Pregnant women should consult their doctor before taking Acivir IV Injection. Do not consume alcohol while being treated with Acivir IV Injection.

Drug Interactions

Drug-Drug Interaction: Acivir IV Injection may interact with painkillers (ibuprofen, naproxen), gout medicines (probenecid), anti-ulcers (cimetidine), immunosuppressants (tacrolimus, ciclosporin, mycophenolate mofetil), anti-depressants (lithium), and respiratory drugs (theophylline).

Drug-Food Interaction: No interactions were found.

Drug-Disease Interaction: Brief your doctor if you have a weakened immune system, breathing problems, an electrolyte imbalance, and liver or kidney diseases before starting Acivir IV Injection.

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • NAPROXEN
  • PROBENECID
  • CIMETIDINE
  • TACROLIMUS
  • CICLOSPORIN
  • MYCOPHENOLATE MOFETIL
  • LITHIUM
  • THEOPHYLLINE

Habit Forming

No

Diet & Lifestyle Advise

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Eat foods rich in antioxidants, such as berries, spinach, kidney beans, dark chocolate, etc.
  • Eat a healthy and balanced diet. Include vitamin and nutrient-rich food such as dark green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system.
  • Opt for lean protein and whole grains.
  • Practise safe sex by using condoms; it helps reduce contact with body fluids from an infected person.
  • Never share personal items that can have your body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.
  • Get tested for other sexually transmitted infections.

Special Advise

You are advised to take proper precautions if you are infected with herpes to prevent the spread of infection to others through sexual contact or body fluids.

Disease/Condition Glossary

Herpes simplex infection: It is commonly known as herpes, a viral infection that causes contagious sores, often around the mouth or genitals. It is caused by the herpes simplex virus. There are two main types of herpes: herpes simplex virus/HSV-1 and HSV-2. HSV-1 causes oral herpes and can be transmitted through oral secretions or sores on the skin. It also spreads through kissing or sharing personal items like toothbrushes or eating utensils. Symptoms of HSV-1 include cold sores or fever blisters around the mouth or on the face. HSV-2/genital herpes causes genital infections, which can be transmitted by direct contact with body fluids or sores/lesions of a herpes-infected individual. Genital herpes is a sexually transmitted infection, and its symptoms include inflamed papules and vesicles on the outer surface of the genitals. 

Shingles: It is a viral infection that is caused by the varicella-zoster virus, the virus that causes chickenpox. The virus stays in the body permanently when a person has suffered chickenpox. The reactivation of this virus after years causes shingles. Symptoms include painful rash or blisters on the skin. 

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Alcohol

Caution

It is advised to avoid alcohol consumption while being treated with Acivir IV Injection to enable your body to fight off infections and reduce the worsening of side effects.

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Pregnancy

Caution

Please seek medical advice if you are pregnant or planning to conceive. Your doctor will prescribe Acivir IV Injection only if the benefits outweigh the risk.

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Breast Feeding

Caution

Acivir IV Injection should be administered to a nursing mother cautiously and only when indicated. Please consult your doctor before taking Acivir IV Injection if you are breastfeeding.

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Driving

Caution

If you notice any symptoms affecting your driving ability while being treated with Acivir IV Injection, do not drive or operate machinery. Drive only when you are alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment before starting Acivir IV Injection.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases/impairment before starting Acivir IV Injection. Dose adjustment may be required.

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Children

Caution

Acivir IV Injection should be used for children only when advised by a doctor. The doctor will prescribe the dosage depending on the child's age and weight.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - ACI0029

Author Details

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FAQs

Acivir IV Injection belongs to the class of 'antivirals' that treats herpes simplex (herpes simplex virus/HSV-1 and HSV-2) infections and varicella-zoster (shingles) infections.
Acivir IV Injection treats viral infections caused by herpes simplex and varicella-zoster viruses by killing and stopping the growth of the virus.
Acivir IV Injection should be used with proper caution and doctor consultation if you have any allergic reactions to medicines, liver or kidney diseases, weakened immune system, breathing problems, and an electrolyte imbalance.
Please consult a doctor before you start Acivir IV Injection if you are undergoing any immunizations/vaccinations, especially vaccines against the varicella virus.
Acivir IV Injection may elevate blood urea and creatinine levels that determine kidney functioning. It may also increase liver enzymes. Hence, seek medical advice before undergoing any laboratory examinations.

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