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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Acivir IV Injection is an antiviral medicine used in the treatment of herpes simplex and varicella-zoster (shingles) infections. This medicine contains aciclovir which works by inhibiting the herpes simplex virus type 1 (HSV-1), 2 (HSV-2), and varicella-zoster virus (VZV), thereby preventing the spread of the infection. Common side effects include nausea, vomiting, loss of appetite, itching, hive-like rash, swelling, and injection site reactions.
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Whats That

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Composition :

ACICLOVIR-25MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Acivir IV Injection

Acivir IV Injection belongs to the class of 'antivirals' that treats herpes simplex (herpes simplex virus/HSV-1 and HSV-2) infections and varicella-zoster (shingles) infections. Herpes simplex infection, commonly known as herpes, is a viral infection that causes contagious sores, often around the mouth or genitals. Shingles is a viral infection with painful rash or blisters on the skin.

Acivir IV Injection is composed of Aciclovir, which works by killing and stopping the growth of herpes simplex virus type 1 (HSV-1), 2 (HSV-2), and varicella-zoster virus (VZV).

Acivir IV Injection will be administered by a healthcare professional; do not self-administer. Common side effects of Acivir IV Injection include nausea, vomiting, loss of appetite, itching, hive-like rash, sensitivity to light (photosensitivity), swelling, redness and tenderness at the injection site. These side effects may not occur in every patient using this medication and gradually resolve over time. If the side effects persist longer or worsen, please seek a doctor's advice.

Let your doctor know if you are allergic to any medications. Inform your doctor if you have a weakened immune system, breathing problems, an electrolyte imbalance, and liver or kidney diseases before starting Acivir IV Injection. Pregnant and breastfeeding women should consult their doctor before starting Acivir IV Injection. It is advised to avoid alcohol consumption while being treated with Acivir IV Injection to enable your body to fight off infections and reduce the worsening of side effects. Acivir IV Injection is given to children only when advised by a doctor based on the child's age and weight.

Uses of Acivir IV Injection

Treatment of Herpes simplex and varicella-zoster (shingles) infections

Directions for Use

Acivir IV Injection will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Acivir IV Injection treats viral infections caused by the herpes simplex and varicella-zoster viruses. It consists of Aciclovir, an antiviral drug. It works by killing and stopping the growth of the virus. Acivir IV Injection effectively treats herpes simplex encephalitis (brain inflammation by herpes simplex virus) and neonatal herpes simplex virus infection. Acivir IV Injection is also useful in preventing the reactivation of the cytomegalovirus infection in seropositive (showing a positive result of a blood test for a particular antibody) patients following bone marrow transplantation.

How Acivir IV Injection Works

Acivir IV Injection is composed of Aciclovir, which works by killing and stopping the growth of herpes simplex virus type 1 (HSV-1), 2 (HSV-2), and varicella-zoster virus (VZV).

Storage

Store in a cool and dry place away from sunlight
Side effects of Acivir IV Injection 10 ml
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Eat foods rich in vitamins C and E, and healthy fats.
  • Consider soft foods like smoothies, soups, and scrambled eggs.
  • Take supplements like vitamins C and E, zinc, and omega-3 fatty acids under medical supervision.
  • Include anti-inflammatory foods like omega-3 rich foods, berries, leafy greens, and spices.
  • Avoid allergens and consider an elimination diet.
  • Practice gentle skin care with non-irritating cleansers and moisturizers.
  • Keep skin well-moisturized with fragrance-free products.
  • Monitor for complications like infection and temperature regulation.
  • If you experience or encounter any severe allergic reaction, stop using medication and consult the doctor right away.
  • Tell your doctor about the allergic reaction, including the medication taken and any symptoms experienced.
  • Your doctor will evaluate the severity of the reaction and determine the best course of action.
  • To ensure a full recovery, follow your doctor's advice, attend scheduled follow-up appointments, and undergo recommended tests to monitor progress and adjust treatment as needed.
Here are the steps to manage angioedema (Swelling Under The Skin) as a side effect of medication:
  • If you experience angioedema, inform your doctor immediately. Treatment can help keep the swelling under control.
  • Seek medical attention if symptoms are severe, such as difficulty breathing or swallowing.
  • Follow your doctor's instructions to manage symptoms, which may include stopping or adjusting the medication that triggered angioedema.
  • Your doctor may also recommend antihistamines, steroids, or other treatments to reduce swelling and inflammation.
  • Make dietary and lifestyle changes as recommended, such as avoiding trigger foods or reducing stress.
  • Monitor your condition closely and track your symptoms to report them to your doctor.
  • Consult your doctor again if symptoms worsen or do not improve or if you experience any new or concerning symptoms.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.

What if I have taken an overdose of Acivir IV Injection

Acivir IV Injection is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include, agitation, seizures, extreme tiredness, loss of consciousness, swelling of the hands, feet, ankles, or lower legs, and decreased urination. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Inform your doctor if you are using prescription, non-prescription drugs, and herbal products before starting Acivir IV Injection. Let your doctor know if you are allergic to any of the components in Acivir IV Injection. Keep your doctor informed of your medical history before starting Acivir IV Injection. Pregnant women should consult their doctor before taking Acivir IV Injection. Do not consume alcohol while being treated with Acivir IV Injection.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Acivir IV Injection 10 ml:
Co-administration of Cidofovir with Acyclovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Acivir IV Injection 10 ml with Cidofovir is not recommended, please consult your doctor before taking it. You should consult a doctor if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, weakness, and palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Acivir IV Injection 10 ml:
Coadministration of Acivir IV Injection 10 ml with Tenofovir alafenamide may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Acivir IV Injection 10 ml with tenofovir alafenamide can result in an interaction. However, if the benefits outweigh the risks, your doctor will prescribe them. Contact a doctor immediately if you experience symptoms such as decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Acivir IV Injection 10 ml:
Coadministration of Acivir IV Injection 10 ml with Amphotericin B can increase the risk or severity of kidney disorder.

How to manage the interaction:
Taking Acivir IV Injection 10 ml with Amphotericin b together can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you experience irregular urination, muscle ache, shortness if breath, or palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Acivir IV Injection 10 ml:
Coadministration of Acivir IV Injection 10 ml with Tenofovir Disoproxil may increase the risk or severity of kidney disorder.

How to manage the interaction:
Coadministration of Acivir IV Injection 10 ml with Tenofovir disoproxil can result in an interaction, it can be taken when your doctor has advised it. Contact a doctor immediately if you experience decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medications without consulting a doctor.
AciclovirIodamide
Severe
How does the drug interact with Acivir IV Injection 10 ml:
Coadministration of Iodamide contrast with Acivir IV Injection 10 ml may increase the risk or severity of kidney injury.

How to manage the interaction:
Before undergoing any imaging procedure let your doctor know you are on Acivir IV Injection 10 ml treatment.
How does the drug interact with Acivir IV Injection 10 ml:
Concomitant use of Acivir IV Injection 10 ml with Tizanidine can increase the risk of developing low blood pressure.

How to manage the interaction:
Coadministration of Acivir IV Injection 10 ml with Tizanidine can result in an interaction, but it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, excessive sweating, or palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Acivir IV Injection 10 ml:
Coadministration of Acivir IV Injection 10 ml with Sirolimus may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Acivir IV Injection 10 ml with Sirolimus can result in an interaction, it can be taken if your doctor has advised it. However, if you experience vomiting, a decrease in hunger, irregular urine, weight gain or loss, swelling, difficulty breathing, muscle pain, or weakness, consult a doctor.
How does the drug interact with Acivir IV Injection 10 ml:
Coadministration of Acivir IV Injection 10 ml with Everolimus may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Acivir IV Injection 10 ml with Everolimus together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, breathing difficulty, muscle pains, dizziness, or palpitations. Do not discontinue any medications without consulting a doctor.
AciclovirMetrizamide
Severe
How does the drug interact with Acivir IV Injection 10 ml:
Coadministration of Metrizamide in contrast with Acivir IV Injection 10 ml may increase the risk or severity of kidney disorder.

How to manage the interaction:
Before undergoing any imaging procedure, let your doctor know you are on Acivir IV Injection 10 ml treatment. Look out for signs such as vomiting, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, or weakness. Consult the doctor immediately.
How does the drug interact with Acivir IV Injection 10 ml:
Co-administration of Acivir IV Injection 10 ml with tacrolimus may increase the risk or severity of kidney problems.

How to manage the interaction:
Coadministration of Acivir IV Injection 10 ml with Tacrolimus can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medications without first consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Eat foods rich in antioxidants, such as berries, spinach, kidney beans, dark chocolate, etc.
  • Eat a healthy and balanced diet. Include vitamin and nutrient-rich food such as dark green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system.
  • Opt for lean protein and whole grains.
  • Practise safe sex by using condoms; it helps reduce contact with body fluids from an infected person.
  • Never share personal items that can have your body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.
  • Get tested for other sexually transmitted infections.

Habit Forming

No

Therapeutic Class

ANTIVIRALS
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Alcohol

Caution

It is advised to avoid alcohol consumption while being treated with Acivir IV Injection to enable your body to fight off infections and reduce the worsening of side effects.

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Pregnancy

Caution

Please seek medical advice if you are pregnant or planning to conceive. Your doctor will prescribe Acivir IV Injection only if the benefits outweigh the risk.

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Breast Feeding

Caution

Acivir IV Injection should be administered to a nursing mother cautiously and only when indicated. Please consult your doctor before taking Acivir IV Injection if you are breastfeeding.

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Driving

Caution

If you notice any symptoms affecting your driving ability while being treated with Acivir IV Injection, do not drive or operate machinery. Drive only when you are alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment before starting Acivir IV Injection.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases/impairment before starting Acivir IV Injection. Dose adjustment may be required.

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Children

Caution

Acivir IV Injection should be used for children only when advised by a doctor. The doctor will prescribe the dosage depending on the child's age and weight.

Have a query?

FAQs

Acivir IV Injection belongs to the class of 'antivirals' that treats herpes simplex (herpes simplex virus/HSV-1 and HSV-2) infections and varicella-zoster (shingles) infections.

Acivir IV Injection treats viral infections caused by herpes simplex and varicella-zoster viruses by killing and stopping the growth of the virus.

Acivir IV Injection should be used with proper caution and doctor consultation if you have any allergic reactions to medicines, liver or kidney diseases, weakened immune system, breathing problems, and an electrolyte imbalance.

Please consult a doctor before you start Acivir IV Injection if you are undergoing any immunizations/vaccinations, especially vaccines against the varicella virus.

Acivir IV Injection may elevate blood urea and creatinine levels that determine kidney functioning. It may also increase liver enzymes. Hence, seek medical advice before undergoing any laboratory examinations.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - ACI0029

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