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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

ACF-SP Tablet is used to reduce pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. It works by blocking the action of an enzyme known as cyclo-oxygenase (COX), which causes pain and swelling in the injured or damaged tissue. Also, it helps in the breakdown of a protein (fibrin) which is formed as a by-product of the blood clot at the site of injury. Thus, it causes thinning of the fluids around the injury site, thereby making fluid drainage smoother in the swollen tissue. It may cause common side effects such as nausea, vomiting, indigestion, stomach pain, etc. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Sharnam Biotech

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About ACF-SP Tablet

ACF-SP Tablet belongs to the class of drugs known as 'non-steroidal anti-inflammatory drugs' (NSAID). It is a fixed-dose combination composed of aceclofenac, paracetamol and serratiopeptidase. ACF-SP Tablet is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. Aceclofenac works by blocking the action of an enzyme known as cyclo-oxygenase (COX), which causes pain and swelling in the injured or damaged tissue. Paracetamol acts as a mild analgesic (pain reducer) and antipyretic (fever reducer), which enhances the pain relief action of aceclofenac. Serratiopeptidase is an enzyme which helps in the breakdown of a protein (fibrin) which is formed as a by-product of the clotted blood at the site of injury. It thus causes thinning of the fluids around the site of injury thereby making fluid drainage smoother in the swollen tissue.

Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is, for a short time, caused by damage to the tissues of the muscle, bone or organs. Chronic pain lasts for life and is caused by nerve damage, osteoarthritis and dental pain due to damage to the tooth nerve, infection, decay, extraction or injury. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal. 

You can take ACF-SP Tablet with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite or break it. Your doctor will advise you on how often you take your tablets based on your medical condition.  Most of the side effects of ACF-SP Tablet do not require medical attention and gradually resolve over time. Common side effects include nausea, vomiting, indigestion, stomach pain, etc. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Do not take ACF-SP Tablet if you are allergic to painkillers like aspirin, ibuprofen, naproxen, or diclofenac. It is not recommended for use in children. It is advisable not to exceed the recommended dose or duration of treatment.

Uses of ACF-SP Tablet

ACF-SP Tablet is used to treat pain after any injury, Low back pain, Cervical pain, Spondylitis, Osteoarthritis, Rheumatoid arthritis, etc. The detailed uses of ACF-SP Tablet are as follows:
•Pain Relief: ACF-SP Tablet relieves mild to moderate pain, such as headaches, toothaches, and post-surgical pain, effectively controlling numerous acute pain disorders.
•Anti-Inflammatory: ACF-SP Tablet also serves to reduce swelling. Because it contains aceclofenac, it has anti-inflammatory characteristics and helps treat inflammatory disorders such as arthritis or sports injuries.
•Fever Reduction: Paracetamol in the ACF-SP Tablet composition, which acts as an antipyretic, helps to reduce fever in various types of situations, including illnesses and infections.
•Post-Surgical Pain Management: ACF-SP Tablet aids in managing post-operative pain, making recovery more comfortable and reducing patient discomfort after surgery.
•Management of Musculoskeletal Disorders: ACF-SP Tablet relieves pain and discomfort caused by musculoskeletal disorders such as lower back pain and joint pain, increasing the quality of life for persons suffering from chronic pain.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

ACF-SP Tablet consists of aceclofenac, paracetamol and serratiopeptidase. Aceclofenac works by blocking the action of an enzyme known as cyclo-oxygenase (COX), which causes pain and swelling in the injured or damaged tissue. Paracetamol acts as a mild analgesic (pain reducer) and antipyretic (fever reducer), which enhances the pain relief action of aceclofenac. Serratiopeptidase causes thinning of the fluids around the site of injury, thereby making fluid drainage smoother in the swollen tissue. Together, these not only reduce pain and inflammation but also help with faster healing.

How ACF-SP Tablet Works

ACF-SP Tablet belongs to the class of drugs known as 'non-steroidal anti-inflammatory drugs' (NSAID). It is a fixed-dose combination composed of aceclofenac, paracetamol and serratiopeptidase. ACF-SP Tablet is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. Aceclofenac works by blocking the action of an enzyme known as cyclo-oxygenase (COX), which causes pain and swelling in the injured or damaged tissue. Paracetamol acts as a mild analgesic (pain reducer) and antipyretic (fever reducer), which enhances the pain relief action of aceclofenac. Serratiopeptidase is an enzyme which helps in the breakdown of a protein (fibrin) which is formed as a by-product of the clotted blood at the site of injury. It thus causes thinning of the fluids around the site of injury thereby making fluid drainage smoother in the swollen tissue.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ACF-SP Tablet

  • Nausea
  • Stomach Pain
  • Loss of appetite
  • Diarrhoea
  • Stomach upset
  • Indigestion

What if I have taken an overdose of ACF-SP Tablet

Do not take more than the prescribed dose of ACF-SP Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Consumption of alcohol should be avoided during the treatment with ACF-SP Tablet as it may lead to an increase in the risk of liver damage. Patients with stomach ulcers, gastric bleeding, severe heart failure and liver or kidney disease should not take ACF-SP Tablet on their own. Besides this, it should be avoided during the last trimester of pregnancy, unless there are compelling reasons for doing so. If you have a severe allergy to painkillers like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, immediately stop taking ACF-SP Tablet . Use with caution in pregnancy and breastfeeding. Do not self-administer ACF-SP Tablet if you are pregnant or are nursing.

Drug-Drug Interactions

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AceclofenacAtenolol
Severe
ParacetamolTeriflunomide
Severe

Drug-Drug Interactions

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AceclofenacAtenolol
Severe
How does the drug interact with ACF-SP Tablet:
Co-administration of Atenolol with ACF-SP Tablet could increase the risk of low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Atenolol and ACF-SP Tablet, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience excessive sweating, shortness of breath, palpitations, or chest discomfort. Do not discontinue any medications without consulting a doctor.
ParacetamolTeriflunomide
Severe
How does the drug interact with ACF-SP Tablet:
Co-administration of Teriflunomide with ACF-SP Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking ACF-SP Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with ACF-SP Tablet:
Co-administration of Lomitapide and ACF-SP Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between ACF-SP Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolKetamine
Severe
How does the drug interact with ACF-SP Tablet:
Co-administration of ketamine and ACF-SP Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and ACF-SP Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolKetoconazole
Severe
How does the drug interact with ACF-SP Tablet:
Co-administration of ACF-SP Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between ACF-SP Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolLeflunomide
Severe
How does the drug interact with ACF-SP Tablet:
Co-administration of ACF-SP Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between ACF-SP Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolOxazepam
Severe
How does the drug interact with ACF-SP Tablet:
Co-administration of ACF-SP Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and ACF-SP Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolMipomersen
Severe
How does the drug interact with ACF-SP Tablet:
Co-administration of Mipomersen with ACF-SP Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between ACF-SP Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with ACF-SP Tablet:
Co-administration of ACF-SP Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between ACF-SP Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, Vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercises like walking on a treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.
  • In the chronic conditions of arthritis or joint pain try to include fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimum level of chemical called cytokines, which ramp up inflammation.
  • Your sitting posture is important especially when have pain and inflammation conditions. Try to sit as little as possible, and only for short time (10-15 min). Use back support like rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

ACF-SP Tablet Substitute

Substitutes safety advice
  • Aceelo PS Tablet 10's

    by Others

    8.80per tablet
  • Zerodol-SP Tablet 10's

    by Others

    12.51per tablet
  • Signoflam Tablet 10's

    by Others

    14.22per tablet
  • Hifenac-SP Tablet 10's

    by Others

    12.02per tablet
  • Hifenac-D Tablet 10's

    by Others

    12.02per tablet
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Alcohol

Unsafe

You are recommended not to consume alcohol along with ACF-SP Tablet to avoid unpleasant side-effects.

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Pregnancy

Caution

ACF-SP Tablet to be taken with caution, specially if you are pregnant. Your doctor may adjust your dose depending upon your conditions, if he/she feels the benefits over weigh the risks.

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Breast Feeding

Caution

Only consume ACF-SP Tablet if it has been prescribed by a doctor as the safety data in nursing mothers is lacking. Inform your doctor if you are breastfeeding.

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Driving

Caution

ACF-SP Tablet may affect driving as it causes dizziness.

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Liver

Caution

ACF-SP Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.

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Kidney

Caution

ACF-SP Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Caution

ACF-SP Tablet should not be given to children without prescription of a child specialist. Your doctor will determine the dose of the medicine depending on your child's weight and severity of condition.

FAQs

ACF-SP Tablet is used to relieve pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. It is used in the treatment of pain after any injury, Low back pain, Cervical pain, Spondylitis, Osteoarthritis, Rheumatoid arthritis, etc.

Yes, in most of the patients it is safe to take ACF-SP Tablet but if it causes any unwanted side effects like diarrhea, vomiting, nausea, please consult your doctor immediately.

ACF-SP Tablet when taken by patients who are allergic to pain-killers or NSAIDs can be harmful. It should also be avoided in person with history of heart failure, kidney or liver disease and stomach ulcers,

A chronic inflammatory disorder affecting many joints, including those in the hands and feet. In rheumatoid arthritis, the body's immune system attacks its own tissue, including joints. In severe cases, it attacks internal organs. Rheumatoid arthritis affects joint linings, causing painful swelling.

Ankylosing spondylitis (AS) is a rare type of arthritis that causes pain and stiffness in your spine. This lifelong condition, also known as Bechterew disease, usually starts in your lower back. It can spread up to your neck or damage joints in other parts of your body.

Country of origin

India
Other Info - ACF0017

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