Acezit-SR Tablet

Acezit-SR Tablet belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) or painkillers. These drugs are used to reduce and relieve pain and inflammation (swelling) associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Arthritis is a condition that affects the joints. Symptoms include swelling, pain, inflammation, stiffness, and tenderness. 

Acezit-SR Tablet contains 'Aceclofenac', which works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. By blocking the effect of COX enzymes, fewer prostaglandins are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

In some cases, Acezit-SR Tablet may cause certain common side effects such as dizziness, diarrhoea, nausea, and increased liver enzymes in the blood. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Acezit-SR Tablet may cause drowsiness and dizziness, so drive with caution. Acezit-SR Tablet is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with Acezit-SR Tablet as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Acezit-SR Tablet belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) used to reduce and relieve pain, redness, and inflammation (swelling) in patients suffering from osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Acezit-SR Tablet works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins, which are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

• Dizziness
• Diarrhoea
• Nausea
• Increased liver enzymes in the blood

If you have had any recent heart surgery, do not take Acezit-SR Tablet as it can increase the risk of heart attack or stroke. Do not take Acezit-SR Tablet if you are allergic to aceclofenac or other NSAIDs (such as ibuprofen, diclofenac or naproxen); if you have stomach ulcers, have suffered bleeding problems, clotting problems, severe heart, liver or kidney problems. Inform your doctor if you have or have had disorders of the stomach, blood circulation problems to the brain, asthma, porphyria (blood disorder), diabetes, high blood pressure, auto-immune diseases, connective tissue diseases; if you are recovering from major surgery or if you are elderly. Consult your doctor if you are pregnant or breastfeeding. Acezit-SR Tablet may cause drowsiness and dizziness, so drive only if you are alert. Acezit-SR Tablet is not recommended for children as safety has not been established. Avoid consuming alcohol along with Acezit-SR Tablet as it could lead to increased drowsiness and may also increase the risk of stomach bleeding. Stop taking Acezit-SR Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Acezit-SR Tablet unless prescribed. 

Drug-Drug Interactions: Acezit-SR Tablet may have interaction with pain killers (aspirin, ibuprofen, naproxen, celecoxib, etoricoxib), anti-depressants (citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, lithium), cardiac glycoside (digoxin), anti-hypertensives (enalapril, lisinopril, losartan, candesartan, hydralazine, methyldopa, clonidine, moxonidine, propranolol), antibiotics (ciprofloxacin, ofloxacin, levofloxacin moxifloxacin), diuretics (furosemide, amiloride hydrochloride), blood thinners (warfarin, heparin, clopidogrel), anti-rheumatoid (methotrexate), steroids (mifepristone), glucocorticoids (hydrocortisone, prednisolone), immunosuppressants (ciclosporin, tacrolimus), anti-HIV (zidovudine), anti-diabetic (glibenclamide, gliclazide, tolbutamide).

Drug-Food Interactions: Avoid consumption of alcohol while taking Acezit-SR Tablet as it might cause increased dizziness and risk of stomach bleeding.

Drug-Disease Interactions: Inform your doctor if you have stomach ulcers, blood disorders, disorders of the stomach, blood circulation problems to the brain, asthma, porphyria, diabetes, high blood pressure, auto-immune diseases, connective tissue diseases, heart, kidney and liver problems.

• ASPIRIN
• IBUPROFEN
• NAPROXEN
• CELECOXIB
• ETORICOXIB
• CITALOPRAM
• ESCITALOPRAM
• FLUOXETINE
• FLUVOXAMINE
• PAROXETINE
• SERTRALINE
• LITHIUM
• DIGOXIN
• ENALAPRIL
• LISINOPRIL
• LOSARTAN
• HYDRALAZINE
• METHYLDOPA
• CLONIDINE
• PROPRANOLOL
• MOXONIDINE
• CIPROFLOXACIN
• OFLOXACIN
• LEVOFLOXACIN
• MOXIFLOXACIN
• FUROSEMIDE
• WARFARIN
• HEPARIN
• CLOPIDOGREL
• METHOTREXATE
• MIFEPRESTONE
• HYDROCORTISONE
• PREDNISOLONE
• CYCLOSPORINE
• TACROLIMUS
• ZIDOVUDINE
• GLIBENCLAMIDE
• GLICLAZIDE
• CANDESARTAN
• AMILORIDE HYDROCHORIDE
• TOLBUTAMIDE

• Physical activity strengthens muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming are helpful.
• Performing yoga may also help in improving joint flexibility and pain management.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
• Follow heat or cold therapy, and regularly apply a cold or hot compress on the joints for 15-20 minutes.
• De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
• Acupuncture, massage and physical therapy may also be helpful.
• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
• Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
• Avoid smoking and alcohol consumption.

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation and tenderness. The main reason for osteoarthritis is age; the older you are, the more likely you are to get osteoarthritis, which is known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons include a past injury such as torn cartilage, dislocated joints and ligament injuries. 

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

Ankylosing spondylitis causes pain and stiffness in the spine. The pain usually starts in the lower back and can spread to the neck, damaged joints, or other parts of the body. Symptoms of ankylosing spondylitis include decreased flexibility, which usually leads to a hunched-forward posture, pain in the back and joints, and stiffness.