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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Abirapro 250 mg Tablet is an anti-androgen medicine used to treat prostate cancer. It contains Abiraterone, which is in a class of medications called androgen biosynthesis inhibitors. It works by decreasing the amount of certain hormones in the body. Common side effects of Abirapro 250 mg Tablet may include nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite, and groin pain.

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Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Abirapro 250 mg Tablet

Abirapro 250 mg Tablet is an anti-androgen medicine used in the treatment of prostate cancer. It is used to treat metastatic castration-resistant prostate cancer (a condition where cancer does not get controlled with hormonal therapy) and metastatic castration-sensitive prostate cancer (a condition where cancer has spread to other parts of the body but can be controlled) in men. Prostate cancer is a condition that occurs when the prostate gland cells increase abnormally. Symptoms may include difficulty in urinating, pain, numbness, etc.

Abirapro 250 mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes an increase in cancer cells in the prostate gland. Abirapro 250 mg Tablet works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. 

Abirapro 250 mg Tablet may cause certain side effects such as nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite and groin pain. These side effects usually disappear without any medical attention. However, if these side effects persist, inform your doctor. Take this medicine as advised by your doctor. It should be taken on an empty stomach at least 2 hours before or after meals. Your doctor will decide the dose of the medicine based on the severity of your disease.

Abirapro 250 mg Tablet should be avoided if you are allergic to it. Inform your doctor if you have any pre-existing or a history of liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, hypokalemia, hypoglycaemia, fluid retention before taking Abirapro 250 mg Tablet . Abirapro 250 mg Tablet is not recommended for use in women and children as the safety and efficacy of this medicine are not established. Inform your doctor of all your ongoing medications to avoid interactions. This medicine is used in combination with prednisolone for the treatment of prostate cancer. 

Uses of Abirapro 250 mg Tablet

Treatment of Prostate Cancer

Directions for Use

Abirapro 250 mg Tablet should be taken on an empty stomach at least two hours before or after a meal. It is advised not to take more than the recommended dose of medicine. Swallow the medicine as a whole with a glass of water. Do not chew or crush or break the medicine.

Medicinal Benefits

Abirapro 250 mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes increase of cancer cells in prostate gland. Abirapro 250 mg Tablet works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. Abirapro 250 mg Tablet is used in combination with prednisolone for the treatment of prostate cancer. It is mainly intended for use in men only.

How Abirapro 250 mg Tablet Works

Abirapro 250 mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes an increase in cancer cells in the prostate gland. Abirapro 250 mg Tablet works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Abirapro 250 mg Tablet

  • Dizziness
  • Heartburn
  • Headache
  • Diarrhoea
  • Muscle Weakness
  • Joint Pain
  • Confusion
  • Hot Flushes
  • Loss of Appetite
  • Groin Pain

What if I have taken an overdose of Abirapro 250 mg Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Abirapro 250 mg Tablet may include fast or irregular heartbeat, lightheadedness, dizziness, or fainting, shortness of breath or difficulty breathing, swelling of the feet, ankles, or lower legs, and unexplained weight gain. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Abirapro 250 mg Tablet should be avoided if you are allergic to it or any other components present in it. Inform your doctor if you have/had any conditions like liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, hypokalemia, hypoglycaemia, fluid retention or taking any other medicines before taking Abirapro 250 mg Tablet as it may cause serious side effects. Abirapro 250 mg Tablet is not recommended for use in women and children as the safety and efficacy of this medicine are not established. This medicine is used in combination with prednisolone for the treatment of prostate cancer.

Drug-Drug Interactions

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AbirateroneZiprasidone
Critical
AbirateroneSaquinavir
Critical

Drug-Drug Interactions

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AbirateroneZiprasidone
Critical
How does the drug interact with Abirapro 250 mg Tablet 120's:
Taking Abirapro 250 mg Tablet 120's with ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Abirapro 250 mg Tablet 120's and ziprasidone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
AbirateroneSaquinavir
Critical
How does the drug interact with Abirapro 250 mg Tablet 120's:
Taking Abirapro 250 mg Tablet 120's with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abirapro 250 mg Tablet 120's and Saquinavir together is not recommended as it can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneThioridazine
Critical
How does the drug interact with Abirapro 250 mg Tablet 120's:
Taking Abirapro 250 mg Tablet 120's with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abirapro 250 mg Tablet 120's and Thioridazine together is not recommended and can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneEliglustat
Critical
How does the drug interact with Abirapro 250 mg Tablet 120's:
Coadministration of Abirapro 250 mg Tablet 120's with Eliglustat can increase the levels of Eliglustat in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Abirapro 250 mg Tablet 120's with Eliglustat is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AbirateroneMesoridazine
Critical
How does the drug interact with Abirapro 250 mg Tablet 120's:
Taking Abirapro 250 mg Tablet 120's with Mesoridazine can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Abirapro 250 mg Tablet 120's and Mesoridazine together is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneEscitalopram
Severe
How does the drug interact with Abirapro 250 mg Tablet 120's:
Using escitalopram together with Abirapro 250 mg Tablet 120's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Escitalopram with Abirapro 250 mg Tablet 120's can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience dizziness, irregular heartbeat, drowsiness, lightheadedness, shortness of breath, vomiting, or shortness of breath, consult a doctor immediately. Do not stop using any medications without consulting a doctor.
AbirateronePanobinostat
Severe
How does the drug interact with Abirapro 250 mg Tablet 120's:
Using Panobinostat together with Abirapro 250 mg Tablet 120's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Abirapro 250 mg Tablet 120's and Panobinostat, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: an irregular heart rhythm, a heart condition, congenital long qt syndrome, conduction abnormalities, severe or prolonged diarrhea, vomiting, complications, sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
AbirateroneSparfloxacin
Severe
How does the drug interact with Abirapro 250 mg Tablet 120's:
Taking Abirapro 250 mg Tablet 120's with Sparfloxacin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abirapro 250 mg Tablet 120's and Sparfloxacin together can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneGatifloxacin
Severe
How does the drug interact with Abirapro 250 mg Tablet 120's:
Taking Abirapro 250 mg Tablet 120's with Gatifloxacin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abirapro 250 mg Tablet 120's with Gatifloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbirateroneQuinidine
Severe
How does the drug interact with Abirapro 250 mg Tablet 120's:
Taking Abirapro 250 mg Tablet 120's with Quinidine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abirapro 250 mg Tablet 120's with Quinidine together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try to take vegetables like cauliflower, cabbage, broccoli, spinach and kale. This food slows the growth of prostate cancer and even reduces the risk of prostate cancer.
  • It is advised to consume fewer dairy products as these foods may increase the risk of prostate cancer. 
  • Physical activity helps in strengthening muscles, reduces fatigue, helps in weight loss and gives strength.
  • Maintain a healthy weight by doing regular simple exercises and yoga. 
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention. 
  • Avoid including red meat high amounts of meat in your diet. When meat is cooked, it may increase the risk of developing prostate cancer.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Abirapro 250 mg Tablet Substitute

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Alcohol

Caution

Interaction of Abirapro 250 mg Tablet with alcohol is unknown. It is advisable to consult your doctor if you have concerns.

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Pregnancy

Not applicable

Not intended for women.

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Breast Feeding

Not applicable

Not intended for women.

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Driving

Caution

Abirapro 250 mg Tablet may decrease alertness or make you feel sleepy and dizzy. So, do not drive or operate heavy machinery while taking Abirapro 250 mg Tablet until your vision improves.

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Liver

Caution

Abirapro 250 mg Tablet should be used with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust the dose based on your condition.

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Kidney

Caution

Abirapro 250 mg Tablet should be used with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust the dose based on your condition.

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Children

Unsafe

Abirapro 250 mg Tablet is not recommended for use in children as the safety and efficacy of this medicine are not established.

FAQs

Abirapro 250 mg Tablet is used to treat Prostate Cancer.
Abirapro 250 mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. It works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.
No, do not stop taking Abirapro 250 mg Tablet without consulting your doctor. It is recommended to take this medicine for the entire prescribed duration, even when symptoms improve or resolve.
The common side-effects of Abirapro 250 mg Tablet are nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite, and groin pain. These side effects usually do not require any medical attention.
Take Abirapro 250 mg Tablet as advised by your doctor. However, if you forget or miss any dose of Abirapro 250 mg Tablet , take it as soon as you remember unless it is time for your next dose. But do not double the dose.
Inform your doctor if you have a pre-existing or a history of liver/kidney disease, hypoglycemia, hypokalemia, bone disorders, adrenocortical insufficiency, fluid retention and cardiovascular conditions before taking Abirapro 250 mg Tablet .
Abirapro 250 mg Tablet is not a cure for prostate cancer. However, it helps manage advanced stages by blocking testosterone production, thereby slowing the growth and progression of the cancer.
No, Abirapro 250 mg Tablet is not a chemotherapy drug. Abirapro 250 mg Tablet is a hormonal therapy that lowers testosterone levels to reduce the growth of prostate cancer.
You need to take prednisolone with Abirapro 250 mg Tablet to reduce the risk of high blood pressure, fluid retention (too much water in your body), and low potassium levels in your blood which may be caused by Abirapro 250 mg Tablet .
Yes, Abirapro 250 mg Tablet can affect the liver. Your healthcare provider will perform blood tests to check your liver function before and during treatment.
Liver function tests (investigation) should be conducted before starting Abirapro 250 mg Tablet and periodically during treatment, as advised by your healthcare provider.
Abirapro 250 mg Tablet should be taken once daily on an empty stomach, at least two hours after eating or one hour before eating. Swallow Abirapro 250 mg Tablet whole with a glass of water; do not chew, crush, or break it. Always follow the recommended dose.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai - 400 026.
Other Info - ABI0021

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