ABCIXIREL 10MG INJECTION 5ML

ABCIXIREL 10MG INJECTION belongs to the group of medicines called 'antiplatelet agents' used to prevent the formation of blood clots, thereby reducing the chance of Myocardial infarction. ABCIXIREL 10MG INJECTION is used as an adjunct during percutaneous coronary intervention (PCI) procedure in patients with unstable angina not responding to conventional medical therapy when PCI procedure is planned within 24 hours.

ABCIXIREL 10MG INJECTION contains Abciximab, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. ABCIXIREL 10MG INJECTION results in reducing the risk of cardiovascular events like myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST).

ABCIXIREL 10MG INJECTION may cause certain side effects such as bleeding, nausea, headache, abdominal pain, hypotension, vomiting, dizziness, back pain, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare professional will administer ABCIXIREL 10MG INJECTION. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

ABCIXIREL 10MG INJECTION should be avoided if you are allergic to it. It is contraindicated in patients who have active internal bleeding, thrombocytopenia, severe uncontrolled hypertension, had recent major surgery or trauma, a history of cerebrovascular accident within the last two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, used dextran before PCI procedure, and history of vasculitis as it can cause serious adverse effects. ABCIXIREL 10MG INJECTION is administered along with aspirin and heparin. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving ABCIXIREL 10MG INJECTION, have/had a recent severe injury or surgery due to risk of severe bleeding problems. If you are pregnant or breastfeeding, inform your doctor before receiving this medicine. ABCIXIREL 10MG INJECTION is not recommended for children below 12 years of age as efficacy and safety have not been established.

ABCIXIREL 10MG INJECTION contains Abciximab, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. ABCIXIREL 10MG INJECTION results in reducing the risk of cardiovascular events like myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST). This medicine is always administered along with aspirin and heparin.

• Bleeding
• Nausea
• Headache
• Abdominal pain
• Hypotension
• Vomiting
• Dizziness
• Back pain
• Pain at the site of injection

Do not receive ABCIXIREL 10MG INJECTION if you are allergic to it. This medicine is contraindicated in patients having active internal bleeding, thrombocytopenia, recent major surgery or trauma, severe uncontrolled hypertension, history of cerebrovascular accident within two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, use of dextran before PCI procedure, and history of vasculitis as it can cause serious adverse effects. ABCIXIREL 10MG INJECTION is administered along with aspirin and heparin. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving ABCIXIREL 10MG INJECTION if you have/had a recent severe injury or surgery due to the risk of severe bleeding problems. If you are pregnant or breastfeeding, inform your doctor before receiving this medicine. ABCIXIREL 10MG INJECTION is not recommended for children below 12 years of age as efficacy and safety have not been established.

Drug-Drug Interactions: ABCIXIREL 10MG INJECTION may interact with pain killers (aspirin, ibuprofen, celecoxib, hydrocodone, tramadol), blood thinners (clopidogrel, dalteparin, enoxaparin, rivaroxaban, prasugrel), ACE Inhibitors (captopril, Enalapril), calcium channel blockers (nifedipine, cilnidipine), beta-blockers (atenolol, sotalol), warfarin, heparin.

Drug-Food Interactions: Avoid smoking and alcohol consumption.

Drug-Disease Interactions: Inform your doctor if you have bleeding problems, coronary and cerebral vascular disease, liver or kidney disease.

• ASPIRIN
• IBUPROFEN
• CELECOXIB
• CLOPIDOGREL
• ENOXAPARIN
• CAPTOPRIL
• ENALAPRIL
• NIFEDIPINE
• CILNIDIPINE
• ATENOLOL
• SOTALOL
• WARFARIN
• HEPARIN

• Eat a diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
• Avoid smoking and alcohol consumption.
• Maintain a healthy weight with proper diet and exercise.
• Managing stress with meditation, yoga, and massage.
• Avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.

• Before administration of ABCIXIREL 10MG INJECTION, a blood test for platelet count, prothrombin time, ACT and APTT should be done to check for any hemostatic abnormalities.
• As ABCIXIREL 10MG INJECTION will be administered along with heparin and aspirin, it is always important to check the patient for any bleeding conditions.

Blood clot: Platelets are small cell particles that circulate in the blood. When the blood vessel is damaged or cut, the platelets clump together and lead to the formation of a clot. Thus, it prevents bleeding. The formation of clots in arteries can cut off the blood supply, leading to heart attack, stroke or death. Clot formation in the arteries that supply blood to the heart may cause reduced blood flow, leading to unstable angina (chest pain).

Myocardial infarction: Myocardial infarction, also known as a heart attack or stroke, could occur due to the lack of blood and oxygen supply in the heart. Symptoms include chest pain, upper body pain, sweating, weakness, trouble breathing, lightheadedness and nausea.