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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Jan 1, 2025 | 2:49 PM IST
AKT-4 Kit is used to treat tuberculosis. It works by preventing the growth of bacteria or killing bacteria. In some cases, you may experience certain common side effects such as weakness, nausea, vomiting, malaise (feeling of discomfort), fatigue and vision problems. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About AKT-4 Kit

AKT-4 Kit is used to treat tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine and bone marrow. AKT-4 Kit does not work against infections caused by the virus, including cold and flu.

AKT-4 Kit is a combination of four anti-tuberculosis drugs: Rifampicin, isoniazid, pyrazinamide and ethambutol. Isoniazid prevents the formation of the bacterial cell wall. At the same time, rifampicin inactivates a bacterial enzyme (RNA-polymerase), which is required by TB bacteria (Mycobacterium tuberculosis) to make essential proteins and to reproduce. Ethambutol and pyrazinamide work by slowing the growth of bacteria. Altogether, they kill the bacteria and treat the infection.

The dose and duration of AKT-4 Kit can vary depending on your condition and the severity of the infection. In some cases, you may experience certain common side effects such as weakness, nausea, vomiting, malaise (feeling of discomfort), fatigue and vision problems. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer, while taking AKT-4 Kit as they might cause interaction. Maintain a gap of one hour between AKT-4 Kit and antacid medicines. Consult your doctor before taking AKT-4 Kit if you are pregnant. Avoid breastfeeding while taking AKT-4 Kit as it passes into breast milk. AKT-4 Kit is not recommended for use in children. AKT-4 Kit may cause dizziness and vision problems, so drive only if you are alert. Avoid consuming alcohol along with AKT-4 Kit as it might lead to liver problems and increased dizziness.

Uses of AKT-4 Kit

Treatment of Tuberculosis (TB).

Medicinal Benefits

AKT-4 Kit belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis. AKT-4 Kit is a combination of four anti-tuberculosis drugs: Rifampicin, isoniazid, pyrazinamide and ethambutol. Isoniazid prevents the formation of the bacterial cell wall. At the same time, rifampicin inactivates a bacterial enzyme (RNA-polymerase), which is required by TB bacteria (Mycobacterium tuberculosis) to make essential proteins and reproduce. Ethambutol and pyrazinamide work by slowing the growth of bacteria. Altogether, they kill the bacteria and treat the infection.

Side Effects of AKT-4 Kit

  • Weakness
  • Nausea
  • Vomiting
  • Malaise (feeling of discomfort)
  • Fatigue
  • Vision problems

Directions for Use

Take AKT-4 Kit 30 minutes before food or 2 hours after food. Swallow AKT-4 Kit as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take AKT-4 Kit if you are allergic to any of its contents, if you have jaundice or if you are taking HIV medicines (saquinavir or ritonavir). Before starting AKT-4 Kit, please inform your doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems. Consult your doctor before taking AKT-4 Kit if you are pregnant. Avoid breastfeeding while taking AKT-4 Kit as it passes into breast milk. AKT-4 Kit is not recommended for use in children. AKT-4 Kit may cause dizziness and vision problems, so drive with caution. Avoid consuming alcohol along with AKT-4 Kit as it might lead to liver problems and increased dizziness.

Therapeutic Class

ANTI- TUBERCULOSIS

Drug-Drug Interactions

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RifampicinSaquinavir
Critical
RifampicinDarunavir
Critical

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Foods rich in vitamin C such as kiwi, broccoli and bell pepper helps in improving the immune system. 
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help in providing relief from cough.
  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer.
  • Quit smoking and avoid alcohol consumption.

Habit Forming

No

How AKT-4 Kit Works

AKT-4 Kit is a combination of four anti-tuberculosis drugs: Rifampicin, isoniazid, pyrazinamide and ethambutol. Isoniazid prevents the formation of the bacterial cell wall. At the same time, rifampicin inactivates a bacterial enzyme (RNA-polymerase), which is required by TB bacteria (Mycobacterium tuberculosis) to make essential proteins and to reproduce. Ethambutol and pyrazinamide work by slowing the growth of bacteria. Altogether, they kill the bacteria and treat the infection.

What if I have taken an overdose of AKT-4 Kit

Do not take more than the prescribed dose of AKT-4 Kit as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
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Alcohol

Unsafe

Avoid alcohol consumption while taking AKT-4 Kit as it could lead to increased dizziness and liver damage.

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Pregnancy

Caution

Please consult your doctor if you are pregnant, your doctor will prescribe AKT-4 Kit only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

AKT-4 Kit passes into breast milk. Do not breastfeed while taking AKT-4 Kit. Consult your doctor for further advice.

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Driving

Unsafe

AKT-4 Kit may cause dizziness, vision problems, numbness and tingling sensation in hands and feet. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking AKT-4 Kit if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease.

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Children

Unsafe

AKT-4 Kit is not recommended for use in children.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - AKT0002

Author Details

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FAQs

AKT-4 Kit belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs but can also spread to other body parts such as kidneys, brain, spine and bone marrow.
AKT-4 Kit is a combination of four anti-tuberculosis drugs, namely: Rifampicin, isoniazid, pyrazinamide, and ethambutol. AKT-4 Kit works by killing the bacteria named Mycobacterium tuberculosis which causes TB (tuberculosis).
Do not stop taking AKT-4 Kit despite symptomatic relief. To treat your condition effectually, continue taking AKT-4 Kit for as long as it has been prescribed for you.
Do not take AKT-4 Kit along with antacids as it might decrease the effectiveness of AKT-4 Kit. Maintain a minimum gap of 1 hour between both. However, please consult your doctor before taking other medicines with AKT-4 Kit.
Consult your doctor before taking AKT-4 Kit with other medicines. Your doctor would suggest the right time, dose and precautions before taking AKT-4 Kit with other drugs.
AKT-4 Kit contains isoniazid which might interact with foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer. Avoid these foods while taking AKT-4 Kit.
AKT-4 Kit might decrease the effectiveness of oral contraceptives (birth control pills). This could lead to an unplanned pregnancy. Instead, use a reliable barrier method of contraception such as condoms or the coil while taking AKT-4 Kit. Consult your doctor if you have any concerns regarding this, your doctor may suggest an alternate method of contraception.
AKT-4 Kit may cause discolouration of teeth, sweat, urine, sputum (phlegm), saliva or tears. The colour in tears may last for some time even after you stop taking AKT-4 Kit. Do not worry as it is a common side-effect of AKT-4 Kit.
Yes, AKT-4 Kit might permanently stain soft contact lenses. Use spectacles and avoid wearing contact lens while taking AKT-4 Kit.
AKT-4 Kit may affect test results of some blood tests such as tests for folate, vitamin B12 and liver function. Inform the person doing the tests that you are taking AKT-4 Kit.
Yes, AKT-4 Kit may cause liver problems, especially in people who are 35 and older. Consult your doctor if you notice symptoms such as yellowing of eyes or skin, dark urine, pale stools, weakness, loss of appetite, nausea or vomiting. Your doctor may advise you to get regular liver tests while taking AKT-4 Kit to check how your liver is functioning.
Take AKT-4 Kit as directed by your doctor. Take AKT-4 Kit on an empty stomach, either one hour before eating or two hours after a meal. Swallow it as whole with a glass of water; do not crush, chew, or break it.
You are recommended to avoid alcohol while taking AKT-4 Kit, as it may cause headache, sweating, dizziness, and feeling lightheaded or faint. Please, consult the doctor if you have any concerns.
Yes, AKT-4 Kit may cause visual impairment (blurred vision, loss of vision). This condition may affect the patient's ability to drive or operate machinery safely. However, if you notice any changes in your vision, stop taking AKT-4 Kit and inform your doctor immediately.
Store AKT-4 Kit at a temperature below 30°C in a cool and dry place as advised on the label. Protect from light and moisture. Keep it out of reach of children. AKT-4 Kit should be disposed, by following local guidelines or asking your pharmacist how to properly dispose of any unused medicine.
AKT-4 Kit causes side effects such as weakness, nausea, vomiting, malaise (feeling of discomfort), and fatigue. However, please contact a doctor if these side effects persist longer.

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