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संयोजन :
टोफासिटिनिब-5एमजी
निर्माता/विपणक :
फाइजर लिमिटेड
सेवन का प्रकार :
मौखिक
वापसी नीति :
वापसी योग्य नहीं
इसके बाद या इसके बाद समाप्त होता है :
Jan-27
Have a query?
Drug-Drug Interactions
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Tofashine 5 mg Tablet:
Taking Itraconazole with Tofashine 5 mg Tablet may increase the risk of side effects.
How to manage the interaction:
Although there is a possible interaction between Tofashine 5 mg Tablet and Itraconazole, they can be taken in case a doctor prescribes it. Consult a doctor if you notice any of the following symptoms: paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, aches in the muscles, shortness of breath, blood in the phlegm, red or irritated skin, body sores, or pain or burning when urinating. Never stop taking any medications without talking to a doctor.
Taking Itraconazole with Tofashine 5 mg Tablet may increase the risk of side effects.
How to manage the interaction:
Although there is a possible interaction between Tofashine 5 mg Tablet and Itraconazole, they can be taken in case a doctor prescribes it. Consult a doctor if you notice any of the following symptoms: paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, aches in the muscles, shortness of breath, blood in the phlegm, red or irritated skin, body sores, or pain or burning when urinating. Never stop taking any medications without talking to a doctor.
How does the drug interact with Tofashine 5 mg Tablet:
Taking Tofashine 5 mg Tablet and Mercaptopurine increases the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Mercaptopurine and Tofashine 5 mg Tablet, you can take these medicines together if prescribed by your doctor. If you experience any of these symptoms - serious infections, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain or burning when you pee - contact your doctor right away. Do not stop using any medications without talking to a doctor.
Taking Tofashine 5 mg Tablet and Mercaptopurine increases the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Mercaptopurine and Tofashine 5 mg Tablet, you can take these medicines together if prescribed by your doctor. If you experience any of these symptoms - serious infections, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain or burning when you pee - contact your doctor right away. Do not stop using any medications without talking to a doctor.
TofacitinibTelithromycin
Severe
How does the drug interact with Tofashine 5 mg Tablet:
When Tofashine 5 mg Tablet is taken with Telithromycin, it can slow down the way the body breaks down Tofashine 5 mg Tablet.
How to manage the interaction:
Taking Tofashine 5 mg Tablet with Telithromycin together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
When Tofashine 5 mg Tablet is taken with Telithromycin, it can slow down the way the body breaks down Tofashine 5 mg Tablet.
How to manage the interaction:
Taking Tofashine 5 mg Tablet with Telithromycin together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
Severe
How does the drug interact with Tofashine 5 mg Tablet:
Taking Tofashine 5 mg Tablet with Temsirolimus may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Tofashine 5 mg Tablet and Temsirolimus, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Taking Tofashine 5 mg Tablet with Temsirolimus may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Tofashine 5 mg Tablet and Temsirolimus, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
TofacitinibAntithymocyte Globulin
Severe
How does the drug interact with Tofashine 5 mg Tablet:
Using Tofashine 5 mg Tablet together with antithymocyte globulin can increase the risk of serious infections.
How to manage the interaction:
Taking Antithymocyte Globulin with Tofashine 5 mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination contact your doctor. Do not discontinue any medications without consulting your doctor.
Using Tofashine 5 mg Tablet together with antithymocyte globulin can increase the risk of serious infections.
How to manage the interaction:
Taking Antithymocyte Globulin with Tofashine 5 mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination contact your doctor. Do not discontinue any medications without consulting your doctor.
Severe
How does the drug interact with Tofashine 5 mg Tablet:
Taking Vedolizumab with Tofashine 5 mg Tablet may increase the risk of infection.
How to manage the interaction:
Taking Tofashine 5 mg Tablet with Vedolizumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination.Do not stop using any medications without a doctor's advice.
Taking Vedolizumab with Tofashine 5 mg Tablet may increase the risk of infection.
How to manage the interaction:
Taking Tofashine 5 mg Tablet with Vedolizumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination.Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Tofashine 5 mg Tablet:
Taking Tofashine 5 mg Tablet with Topotecan may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Tofashine 5 mg Tablet and Topotecan, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Taking Tofashine 5 mg Tablet with Topotecan may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Tofashine 5 mg Tablet and Topotecan, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Severe
How does the drug interact with Tofashine 5 mg Tablet:
Taking Tofashine 5 mg Tablet with Dactinomycin may increase the risk of serious infection.
How to manage the interaction:
Taking Dactinomycin with Tofashine 5 mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any complications, infections, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain or burning when you pee, make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
Taking Tofashine 5 mg Tablet with Dactinomycin may increase the risk of serious infection.
How to manage the interaction:
Taking Dactinomycin with Tofashine 5 mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any complications, infections, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain or burning when you pee, make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
Severe
How does the drug interact with Tofashine 5 mg Tablet:
Co-administration of Tofashine 5 mg Tablet with Capecitabine may increase the risk of serious and potential infections.
How to manage the interaction:
Although there is an interaction, Capecitabine can be taken with Tofashine 5 mg Tablet if prescribed by the doctor. Consult the prescriber if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue the medication without consulting a doctor.
Co-administration of Tofashine 5 mg Tablet with Capecitabine may increase the risk of serious and potential infections.
How to manage the interaction:
Although there is an interaction, Capecitabine can be taken with Tofashine 5 mg Tablet if prescribed by the doctor. Consult the prescriber if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Tofashine 5 mg Tablet:
Taking Etanercept with Tofashine 5 mg Tablet can increase the risk of serious infections as well as sometimes may lead to cancers.
How to manage the interaction:
Although there is a possible interaction between Tofashine 5 mg Tablet and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
Taking Etanercept with Tofashine 5 mg Tablet can increase the risk of serious infections as well as sometimes may lead to cancers.
How to manage the interaction:
Although there is a possible interaction between Tofashine 5 mg Tablet and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Tofashine 5 mg Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofashine 5 mg Tablet, as it can lead to an interaction.
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Tofashine 5 mg Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofashine 5 mg Tablet, as it can lead to an interaction.
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शराब
सावधानी
यह ज्ञात नहीं है कि शराब टोफाशाइन 5 मिलीग्राम टैबलेट 10 के साथ परस्पर क्रिया करती है या नहीं, इसलिए कृपया डॉक्टर से परामर्श लें।
गर्भावस्था
असुरक्षित
गर्भावस्था के दौरान टोफाशाइन 5 मिलीग्राम टैबलेट 10 नहीं लेना चाहिए। यदि आप गर्भधारण करने योग्य महिला हैं, तो टोफाशाइन 5 मिलीग्राम टैबलेट 10 के साथ उपचार के दौरान और बंद करने के 4 सप्ताह बाद तक प्रभावी गर्भनिरोधक का उपयोग करें।
स्तनपान
असुरक्षित
टोफाशाइन 5 मिलीग्राम टैबलेट 10 लेते समय स्तनपान कराने से बचें। अगर आपको कोई चिंता है तो कृपया डॉक्टर से सलाह लें।
ड्राइविंग
सुरक्षित
आम तौर पर टोफाशाइन 5 मिलीग्राम टैबलेट 10 आपकी गाड़ी चलाने की क्षमता को प्रभावित नहीं करता है। हालाँकि, गाड़ी तभी चलाएँ या मशीनरी का संचालन करें जब आप सतर्क हों।
जिगर
सावधानी
लीवर की दुर्बलता वाले रोगियों में खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको लीवर की कोई समस्या है या इस बारे में कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें। गंभीर लीवर की समस्याओं वाले रोगियों के लिए टोफाशाइन 5 मिलीग्राम टैबलेट 10 की अनुशंसा नहीं की जाती है।
गुर्दा
सावधानी
गुर्दे की दुर्बलता वाले रोगियों में खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको गुर्दे की कोई समस्या है या इस बारे में कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें।
बच्चे
असुरक्षित
18 साल से कम उम्र के बच्चों के लिए टोफाशाइन 5 मिलीग्राम टैबलेट 10 की अनुशंसा नहीं की जाती है क्योंकि सुरक्षा और प्रभावशीलता स्थापित नहीं की गई थी।
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