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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Naprosyn Syrup is used to reduce pain and swelling in muscles and joints in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness in the backbone), cervical spondylitis (wear and tear of spinal discs in the neck) and acute gout (severe pain due to excess of uric acid). It contains Naproxen, which works by reducing the production of chemicals, known as prostaglandins, that cause pain and swelling. In some cases, you may experience indigestion, heartburn, stomach pain, nausea, headache, dizziness, drowsiness, bruising, itching, rash, and ringing in your ears. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Naprosyn Syrup 60 ml:
Coadministration of Ketorolac with Naprosyn Syrup 60 ml can increase the risk or severity of gastric bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac with Naprosyn Syrup 60 ml together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Naprosyn Syrup 60 ml:
Taking cidofovir with Naprosyn Syrup 60 ml may increase the risk or severity of kidney problems

How to manage the interaction:
Taking Naprosyn Syrup 60 ml with Cidofovir is generally avoided as it can possibly result in an interaction. You should seek immediate medical attention if you develop signs and symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.
How does the drug interact with Naprosyn Syrup 60 ml:
Co-administration of Naprosyn Syrup 60 ml with Meloxicam can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Meloxicam with Naprosyn Syrup 60 ml is not advised as it can possibly result in an interaction, it can be taken if your doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness.
How does the drug interact with Naprosyn Syrup 60 ml:
Coadministration of Naprosyn Syrup 60 ml and Tenofovir alafenamide may increase the effectiveness of Tenofovir alafenamide.

How to manage the interaction:
There may be a possible interaction between Naprosyn Syrup 60 ml and Tenofovir alafenamide, but they can be taken together if they are prescribed by doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, consult the doctor. Do not discontinue any medication without a doctor's advice.
NaproxenRofecoxib
Severe
How does the drug interact with Naprosyn Syrup 60 ml:
Coadministration of Naprosyn Syrup 60 ml and Rofecoxib can increase the risk or severity of stomach bleeding and rarely lead to serious blood loss.

How to manage the interaction:
There may be a possible interaction between Naprosyn Syrup 60 ml and Rofecoxib, but they can be taken together if they are prescribed by doctor. However, if you experience unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness, consult the doctor. Do not discontinue any medication without a doctor's advice.
NaproxenIodamide
Severe
How does the drug interact with Naprosyn Syrup 60 ml:
Coadministration of Naprosyn Syrup 60 ml and iodamide may increase the effectiveness of iodamide.

How to manage the interaction:
There may be a possible interaction between Naprosyn Syrup 60 ml and Iodamide, but they can be taken together if they are prescribed by doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm and weakness consult the doctor. Do not discontinue any medication without a doctor's advice.
NaproxenIopromide
Severe
How does the drug interact with Naprosyn Syrup 60 ml:
Coadministration of Naprosyn Syrup 60 ml and iopromide may increase the effectiveness of iopromide.

How to manage the interaction:
There may be a possible interaction between Naprosyn Syrup 60 ml and Iopromide but they can be taken together if they are prescribed by doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm and weakness consult the doctor. Do not discontinue any medication without a doctor's advice.
NaproxenLomitapide
Severe
How does the drug interact with Naprosyn Syrup 60 ml:
Coadministration of Naprosyn Syrup 60 ml and Lomitapide may increase the risk or severity of liver problems.

How to manage the interaction:
Taking Naprosyn Syrup 60 ml and Lomitapide together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, confusion, diarrhea, vomiting, muscle weakness, muscle incoordination, tremor, blurred vision, ringing in the ear, excessive thirst, and/or increased urination, consult the doctor. Do not discontinue any medication without a doctor's advice.
How does the drug interact with Naprosyn Syrup 60 ml:
Co-administration of Naprosyn Syrup 60 ml with Alendronic acid may increase the risk or severity of side effects.

How to manage the interaction:
Taking Naprosyn Syrup 60 ml with Alendronic acid together can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you develop severe stomach pain, bloating, sudden dizziness, lightheadedness, vomiting (especially with blood), nausea, loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Naprosyn Syrup 60 ml:
Coadministration of Naprosyn Syrup 60 ml and Ibuprofen can increase the risk or severity of bleeding, ulceration, and rarely leading to serious blood loss.

How to manage the interaction:
Taking Naprosyn Syrup 60 ml and Ibuprofen together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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