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Drug-Drug Interactions
MethotrexateEtretinate
Critical
Severe
Drug-Drug Interactions
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MethotrexateEtretinate
Critical
How does the drug interact with Methotex 1000 mg Injection 40 ml:
Co-administration of Etretinate with Methotex 1000 mg Injection 40 ml may increase the risk or severity of liver problems.
How to manage the interaction:
Taking Etretinate with Methotex 1000 mg Injection 40 ml is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
Co-administration of Etretinate with Methotex 1000 mg Injection 40 ml may increase the risk or severity of liver problems.
How to manage the interaction:
Taking Etretinate with Methotex 1000 mg Injection 40 ml is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Methotex 1000 mg Injection 40 ml:
Coadministration of Methotex 1000 mg Injection 40 ml with ibuprofen can increase the effect and side effects of Methotex 1000 mg Injection 40 ml.
How to manage the interaction:
Although there is a possible interaction between Methotex 1000 mg Injection 40 ml and ibuprofen, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, pallor, dizziness or fainting, unusual bruising or bleeding, seizures, infection; as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
Coadministration of Methotex 1000 mg Injection 40 ml with ibuprofen can increase the effect and side effects of Methotex 1000 mg Injection 40 ml.
How to manage the interaction:
Although there is a possible interaction between Methotex 1000 mg Injection 40 ml and ibuprofen, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, pallor, dizziness or fainting, unusual bruising or bleeding, seizures, infection; as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
Severe
How does the drug interact with Methotex 1000 mg Injection 40 ml:
Co-administration of Methotex 1000 mg Injection 40 ml with Indomethacin can increase the levels and side effects of Methotex 1000 mg Injection 40 ml.
How to manage the interaction:
Although there is a possible interaction between Methotex 1000 mg Injection 40 ml and Indomethacin, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms like mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), infection, as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
Co-administration of Methotex 1000 mg Injection 40 ml with Indomethacin can increase the levels and side effects of Methotex 1000 mg Injection 40 ml.
How to manage the interaction:
Although there is a possible interaction between Methotex 1000 mg Injection 40 ml and Indomethacin, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms like mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), infection, as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
How does the drug interact with Methotex 1000 mg Injection 40 ml:
Combine use of hydroxychloroquine with Methotex 1000 mg Injection 40 ml may increase the effectiveness of everolimus.
How to manage the interaction:
Although there is a possible interaction between hydroxychloroquine and Methotex 1000 mg Injection 40 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult your doctor. Do not stop using any medications without first consulting to your doctor.
Combine use of hydroxychloroquine with Methotex 1000 mg Injection 40 ml may increase the effectiveness of everolimus.
How to manage the interaction:
Although there is a possible interaction between hydroxychloroquine and Methotex 1000 mg Injection 40 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult your doctor. Do not stop using any medications without first consulting to your doctor.
How does the drug interact with Methotex 1000 mg Injection 40 ml:
Combine use of tenofovir alafenamide with Methotex 1000 mg Injection 40 ml may increase the levels or side effects of tenofovir alafenamide.
How to manage the interaction:
Although there is a possible interaction between tenofovir alafenamide and Methotex 1000 mg Injection 40 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult your doctor. Do not stop using any medications without consulting your doctor.
Combine use of tenofovir alafenamide with Methotex 1000 mg Injection 40 ml may increase the levels or side effects of tenofovir alafenamide.
How to manage the interaction:
Although there is a possible interaction between tenofovir alafenamide and Methotex 1000 mg Injection 40 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult your doctor. Do not stop using any medications without consulting your doctor.
Severe
How does the drug interact with Methotex 1000 mg Injection 40 ml:
Coadministration of trimethoprim with Methotex 1000 mg Injection 40 ml can increase the risk or severity of blood disorders.
How to manage the interaction:
Although there is a possible interaction between trimethoprim and Methotex 1000 mg Injection 40 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as pale skin, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not stop using any medications without consulting to a doctor.
Coadministration of trimethoprim with Methotex 1000 mg Injection 40 ml can increase the risk or severity of blood disorders.
How to manage the interaction:
Although there is a possible interaction between trimethoprim and Methotex 1000 mg Injection 40 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as pale skin, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not stop using any medications without consulting to a doctor.
Severe
How does the drug interact with Methotex 1000 mg Injection 40 ml:
Coadministration of Methotex 1000 mg Injection 40 ml with tolmetin can increase the levels and side effects of Methotex 1000 mg Injection 40 ml.
How to manage the interaction:
Although there is a possible interaction between tolmetin and Methotex 1000 mg Injection 40 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
Coadministration of Methotex 1000 mg Injection 40 ml with tolmetin can increase the levels and side effects of Methotex 1000 mg Injection 40 ml.
How to manage the interaction:
Although there is a possible interaction between tolmetin and Methotex 1000 mg Injection 40 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
MethotrexateNitrous oxide
Severe
How does the drug interact with Methotex 1000 mg Injection 40 ml:
Combine use of nitrous oxide with Methotex 1000 mg Injection 40 ml may increase the levels and side effects of nitrous oxide.
How to manage the interaction:
Although there is a possible interaction between nitrous oxide and Methotex 1000 mg Injection 40 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, pale skin, easy bruising or bleeding, unusual weakness, mouth sores, black or bloody stools, and decreased urine output, consult the doctor. Do not discontinue any medications without doctors advice.
Combine use of nitrous oxide with Methotex 1000 mg Injection 40 ml may increase the levels and side effects of nitrous oxide.
How to manage the interaction:
Although there is a possible interaction between nitrous oxide and Methotex 1000 mg Injection 40 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, pale skin, easy bruising or bleeding, unusual weakness, mouth sores, black or bloody stools, and decreased urine output, consult the doctor. Do not discontinue any medications without doctors advice.
Severe
How does the drug interact with Methotex 1000 mg Injection 40 ml:
Using thalidomide together with Methotex 1000 mg Injection 40 ml can increase the risk of developing blood clots.
How to manage the interaction:
Although there is a possible interaction between thalidoamide and Methotex 1000 mg Injection 40 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness or swelling in an arm or leg, consult your doctor. Do not stop using any medications without consulting to a doctor.
Using thalidomide together with Methotex 1000 mg Injection 40 ml can increase the risk of developing blood clots.
How to manage the interaction:
Although there is a possible interaction between thalidoamide and Methotex 1000 mg Injection 40 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness or swelling in an arm or leg, consult your doctor. Do not stop using any medications without consulting to a doctor.
Severe
How does the drug interact with Methotex 1000 mg Injection 40 ml:
Coadministration of Methotex 1000 mg Injection 40 ml with tofacitinib can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between tofacitinib and Methotex 1000 mg Injection 40 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin and pain or burning during urination, consult a doctor. Do not stop using any medications without consulting to a doctor.
Coadministration of Methotex 1000 mg Injection 40 ml with tofacitinib can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between tofacitinib and Methotex 1000 mg Injection 40 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin and pain or burning during urination, consult a doctor. Do not stop using any medications without consulting to a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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शराब
Unsafe
आपको मेथोटेक्स 1000 मिलीग्राम इंजेक्शन 40 मिली लेते समय शराब के सेवन से बचने की सलाह दी जाती है।
गर्भावस्था
Unsafe
मेथोटेक्स 1000 मिलीग्राम इंजेक्शन 40 मिली से गंभीर जन्म दोष हो सकते हैं। गर्भवती होने पर मेथोटेक्स 1000 मिलीग्राम इंजेक्शन 40 मिली लेने की अनुशंसा नहीं की जाती है।
स्तनपान
Unsafe
मेथोटेक्स 1000 मिलीग्राम इंजेक्शन 40 मिली स्तन के दूध में चला जाता है। मेथोटेक्स 1000 मिलीग्राम इंजेक्शन 40 मिली से उपचार के दौरान और अंतिम खुराक के कम से कम 1 सप्ताह बाद तक स्तनपान कराने से बचें।
ड्राइविंग
Caution
मेथोटेक्स 1000 मिलीग्राम इंजेक्शन 40 मिली के कारण चक्कर आना और थकान हो सकती है; जब तक आप यह न जान लें कि मेथोटेक्स 1000 मिलीग्राम इंजेक्शन 40 मिली आप पर किस प्रकार प्रभाव डालता है, तब तक वाहन न चलाएं या भारी मशीनरी का संचालन न करें।
जिगर
Caution
यदि आपको यकृत की समस्या है तो कृपया मेथोटेक्स 1000 मिलीग्राम इंजेक्शन 40 मिली लेने से पहले अपने चिकित्सक से परामर्श करें।
किडनी
Caution
यदि आपको गुर्दे की समस्या है तो कृपया मेथोटेक्स 1000 मिलीग्राम इंजेक्शन 40 मिली लेने से पहले अपने चिकित्सक से परामर्श करें।
बच्चे
Caution
बच्चों में मेथोटेक्स 1000 मिलीग्राम इंजेक्शन 40 मिली की प्रभावकारिता और सुरक्षा पॉलीआर्टिकुलर-कोर्स जुवेनाइल रूमेटोइड गठिया और कैंसर कीमोथेरेपी में स्थापित की गई है। अगर आपको बच्चों में मेथोटेक्स 1000 मिलीग्राम इंजेक्शन 40 मिली के उपयोग के बारे में कोई चिंता है, तो कृपया अपने डॉक्टर से परामर्श करें।
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