TOLPERISONE+PARACETAMOL
About
TOLPERISONE+PARACETAMOL is used to treat muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort caused by the muscle spasm. A muscle spasm occurs due to involuntary contractions of a muscle. A spasm may be a twitch in the muscle or may feel tight or hard, like a knot.
TOLPERISONE+PARACETAMOL is a combination of two drugs: Tolperisone (muscle relaxant) and Paracetamol (pain killer). Tolperisone works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.
Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of TOLPERISONE+PARACETAMOL include nausea, vomiting, dry mouth, dizziness, weakness and sleepiness. These side effects are not familiar to everyone and vary individually.
Let your doctor know if you use any prescription and non-prescription medications before starting TOLPERISONE+PARACETAMOL. Inform your doctor if you have any liver, heart or kidney diseases, myasthenia gravis (fatigue of muscles) and phenylketonuria (a genetic disorder that causes an amino acid build-up, phenylalanine) and alcohol dependency. Consult your doctor before taking TOLPERISONE+PARACETAMOL if you are pregnant or planning for pregnancy. TOLPERISONE+PARACETAMOL may cause dizziness, so drive only if you are alert and focused. TOLPERISONE+PARACETAMOL should not be given to children as safety has not been established. Avoid consuming alcohol and TOLPERISONE+PARACETAMOL as it could lead to increased dizziness and risk of liver damage.
Uses of TOLPERISONE+PARACETAMOL
Medicinal Benefits
TOLPERISONE+PARACETAMOL treats muscle spasms and consists of Tolperisone (muscle relaxant) and Paracetamol (pain killer). Tolperisone is a centrally-acting muscle relaxant. It works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, fewer PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.
Directions for Use
Storage
Side Effects of TOLPERISONE+PARACETAMOL
- Nausea
- Vomiting
- Dry mouth
- Dizziness
- Weakness
- Sleepiness
In-Depth Precautions and Warning
Drug Warnings
Inform your doctor if you have any liver, heart or kidney diseases, myasthenia gravis (fatigue of muscles), phenylketonuria (a genetic disorder that causes a build-up of an amino acid, phenylalanine), and alcohol dependency before starting TOLPERISONE+PARACETAMOL. Consult your doctor before taking TOLPERISONE+PARACETAMOL if you are pregnant, planning for pregnancy or breastfeeding. TOLPERISONE+PARACETAMOL may cause dizziness, so drive only if you are alert and focused. Avoid consuming alcohol along with TOLPERISONE+PARACETAMOL as it could lead to increased dizziness and risk of liver damage. TOLPERISONE+PARACETAMOL is not recommended in children as safety and efficacy is not established.
Drug Interactions
Drug-Drug Interactions: TOLPERISONE+PARACETAMOL may interact with anticoagulants (warfarin), drugs treating vomiting (metoclopramide, domperidone), cholesterol-lowering medications (cholestyramine) and anti-cancer medications (imatinib).
Drug-Food Interactions: Alcohol consumption may cause dizziness and increases the risk of liver damage.
Drug-Disease Interactions: Before using TOLPERISONE+PARACETAMOL, let your doctor know if you have any liver, heart or kidney diseases, myasthenia gravis (fatigue of muscles), phenylketonuria (a genetic disorder that causes a build-up of an amino acid, phenylalanine), and alcohol dependency.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended to avoid alcohol consumption while taking TOLPERISONE+PARACETAMOL. Alcohol intake, along with TOLPERISONE+PARACETAMOL, may cause increased dizziness and risk of liver damage.
Pregnancy
cautionTOLPERISONE+PARACETAMOL should be used with caution during pregnancy. Please consult your doctor before taking TOLPERISONE+PARACETAMOL.
Breast Feeding
cautionTOLPERISONE+PARACETAMOL should be used with caution during breastfeeding. Please consult your doctor before taking TOLPERISONE+PARACETAMOL.
Driving
cautionTOLPERISONE+PARACETAMOL may make you feel dizzy. Do not drive or operate machinery if you experience dizziness.
Liver
cautionPlease consult your doctor since TOLPERISONE+PARACETAMOL should be used with caution in patients with liver impairment/liver disease.
Kidney
cautionPlease consult your doctor since TOLPERISONE+PARACETAMOL should be used with caution in patients with kidney impairment/kidney disease.
Children
unsafeTOLPERISONE+PARACETAMOL is not recommended in children as safety and efficacy is not established.
Habit Forming
Diet & Lifestyle Advise
- Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
- Massages can also be helpful.
- Avoid freezing and hot temperatures.
- Avoid wearing tight-fitting clothes, instead, wear loose garments.
- Rest well and get plenty of sleep.
- To avoid developing pressure sores, change your position at least every two hours.
- Hot or cold therapy can haelp treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
- Stay hydrated, drink plenty of water.
Special Advise
- Let your doctor know that you are taking TOLPERISONE+PARACETAMOL if you are undergoing any medical tests.
- TOLPERISONE+PARACETAMOL may cause fluid retention (oedema), hence it is advised to monitor blood pressure and cardiovascular status in patients with a heart failure history.
- Explain a detail history to the doctor as use of TOLPERISONE+PARACETAMOL is contraindicated in patients with myasthenia gravis.
Patients Concern
Disease/Condition Glossary
Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.
Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. A spasm may be a twitch in the muscle or may feel tight or hard, like a knot.
FAQs
TOLPERISONE+PARACETAMOL is used to treat muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort caused by the muscle spasm.
TOLPERISONE+PARACETAMOL is a combination of two drugs: Tolperisone and Paracetamol. Tolperisone works on the spinal cord and brain to relieve contraction or muscle stiffness. Paracetamol works by blocking the action of certain chemical messengers that cause pain.
TOLPERISONE+PARACETAMOL is usually used for a short period and can be discontinued if there is no pain. However, it should be continued if advised by the doctor.
TOLPERISONE+PARACETAMOL is to be carefully administered in patients with alcohol dependency, kidney or liver damage, myasthenia gravis (fatigue of muscles) and phenylketonuria (a genetic disorder that causes the build-up of an amino acid, phenylalanine). Please consult your doctor before starting TOLPERISONE+PARACETAMOL if you have a medical history.
TOLPERISONE+PARACETAMOL may cause stomach upset; hence taking it with food will prevent you from getting an upset stomach.
