Rosiglitazone
About Rosiglitazone
Rosiglitazone belongs to the group of antidiabetic medicines called thiazolidinedione used to treat type II diabetes. Type II diabetes mellitus is a condition wherein the body doesn’t use insulin effectively, which causes unusual blood glucose levels. Type II diabetes patients either do not create enough insulin, or the insulin they do make does not accomplish its purpose in the body (insulin resistance). This condition mostly occurs in middle-aged or older patients.
Rosiglitazone contains Rosiglitazone, which works by helping your body make better use of the insulin it produces. Rosiglitazone should be taken along with diet management and exercise to control blood sugar levels.
Rosiglitazone may cause certain side effects, such as vomiting, nausea, abdominal pain, headache, upper respiratory tract infections, and muscle pain. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Rosiglitazone should be taken as prescribed by your doctor. It can be taken with or without food. The dose of the medicine will be decided by the doctor based on your disease condition.
Rosiglitazone should be avoided if you are allergic to any of its components. Inform the doctor about your medical history and the medicines you are taking, including herbs and supplements, before starting the treatment with Rosiglitazone. This can help prevent unwanted effects. Rosiglitazone should not be taken if you have type 1 diabetes mellitus, have/ had heart failure in the past, or diabetic ketoacidosis. Consult the doctor if you are pregnant or breastfeeding. It is not recommended for use in children below 18 years of age. Use of Rosiglitazone along with insulin is contraindicated.
Uses of Rosiglitazone
Medicinal Benefits
Rosiglitazone contains Rosiglitazone, which belongs to the thiazolidinedione class of drugs. This medicine helps control the sugar level in your blood when you have type 2 diabetes by helping your body make better use of the insulin it produces. Rosiglitazone should be taken along with diet management and exercise to control blood sugar levels.
Directions for Use
Storage
Side Effects of Rosiglitazone
- Headache
- Nausea
- Upper respiratory tract infections
- Vomiting
- Muscle pain
- Abdominal pain
Drug Warnings
Rosiglitazone should be avoided if you are allergic to any of its components. Inform your doctor about your medical history and the medicines you are taking, including herbs and supplements, before starting the treatment with Rosiglitazone; this can help prevent unwanted effects. Rosiglitazone should not be taken if you have type 1 diabetes mellitus, have/ had heart failure in the past, or diabetic ketoacidosis. Consult the doctor if you are pregnant or breastfeeding. It is not recommended for use in children below 18 years of age. Use of Rosiglitazone along with insulin is contraindicated.
Drug Interactions
Drug-Drug Interactions: Rosiglitazone may interact with antidiabetics (gemfibrozil) and antibiotics (rifampicin). So, tell your doctor if you are using these drugs before taking Rosiglitazone.
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Inform your doctor if you have any kidney or liver disease or heart problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorIt is unknown whether Rosiglitazone will interact with alcohol. Please consult a doctor before consuming alcohol while on treatment with Rosiglitazone.
Pregnancy
cautionIf you are pregnant, or planning pregnancy inform your doctor before receiving Rosiglitazone. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Breast Feeding
cautionIf you are breastfeeding, inform your doctor before receiving Rosiglitazone. Your doctor may suggest you to discontinue nursing or discontinue Rosiglitazone, considering the importance of the drug to the mother.
Driving
consult your doctorIt is not known if Rosiglitazone affects your ability to drive. Drive only if you are alert.
Liver
cautionUse Rosiglitazone with caution, especially if you have a history of liver disease. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Kidney
cautionUse Rosiglitazone with caution, especially if you have a history of kidney disease. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Children
unsafeRosiglitazone is not recommended for children below 18 years as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Try doing 30 minutes of moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise weekly.
- Include your diet with whole grain foods, fruits, vegetables and other fibre-enriched foods.
- Add omega-3 fatty acid-containing oils for daily cooking.
- Avoid taking too much stress as it may elevate your blood sugar level. You can adopt stress management techniques like mindfulness, meditation, or yoga to control stress-related blood sugar changes.
- Loose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
- Keep your blood pressure as normal (140/90) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.
- Avoid smoking and alcohol consumption while on treatment with Rosiglitazone.
- Take short, frequent meals, and avoid prolonged fasting when taking Rosiglitazone.
Special Advise
- Rosiglitazone may sometimes cause hypoglycemia (low blood sugar levels) as a side effect. Try to carry candies or sugar biscuits in your pocket every time you feel symptoms such as sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc.
- Inform your physician about all your underlying conditions, like kidney disease or liver disease, prior heart attack, alcohol intake, etc.
- Lifestyle modifications are the most important step in controlling blood sugar levels.
- Your doctor may advise frequent blood tests to check your blood sugar levels.
Patients Concern
Disease/Condition Glossary
Type II Diabetes Mellitus: It is a chronic and lifelong condition wherein the body doesn’t use insulin effectively, which causes unusual blood glucose levels. Therefore, people affected with type 2 diabetes either do not produce enough insulin or there is resistance to the action of insulin. Middle-aged or older people are most likely to suffer from type 2 diabetes, which is also known as adult-onset diabetes. Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, weight gain, and blurred vision. The complication of type 2 diabetes also includes neuropathy (nerve problems), nephropathy (kidney problems), retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction, and increased chance of heart attack or stroke.
FAQs
Rosiglitazone is used to treat Type II Diabetes Mellitus.
Rosiglitazone contains Rosiglitazone, which helps control the sugar level in your blood when you have type 2 diabetes by helping your body make better use of the insulin it produces.
Yes, Rosiglitazone can cause a minor upset of the stomach. However, do not stop taking it. Discuss with your doctor in case of severe stomach upset.
No, concomitant use of Rosiglitazone along with insulin is not recommended due to serious side effects. Hence, inform your doctor beforehand if you are taking insulin already.
If you forget to take Rosiglitazone, take it as soon as you remember. However, if it's time for the next dose, avoid taking it and do not double the dose to make up for your forgotten dose. Taking an overdose might cause your sugar level to fall down rapidly.
No, Rosiglitazone is not recommended for patients below 18 years as the safety and effectiveness were not established.
You are recommended to consult your doctor before taking Rosiglitazone with glimepiride or other medicines to avoid possible interactions.
Take Rosiglitazone with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not break, chew or crush it.
Rosiglitazone increases the permeability of fluid in capillaries (tiny blood vessels) which makes the movement of fluids easier across the membrane and their consequent accumulation, resulting in oedema (puffiness). Also, it increases water and sodium reabsorption from the kidney which contributes to the oedema.
Rosiglitazone can cause edema and fluid retention. Thus, there is excess fluid in the body (fluid overload). As a result, it may cause heart failure (which worsens with fluid overload in those at risk).
Rosiglitazone may be beneficial in treating depression. However, take your doctor’s advice before using Rosiglitazone.
Rosiglitazone may cause side effects such as headache, nausea, vomiting, abdominal pain, muscle pain or upper respiratory tract infections. If any of these side effects persist or worsen, please consult your doctor.
