OZAGREL HYDROCHLORIDE
About
OZAGREL HYDROCHLORIDE belongs to a class of selective thromboxane A2 synthase inhibitors. It is usually used to improve cerebrovascular spasms and associated symptoms of cerebral ischemia after surgery for subarachnoid haemorrhage and movement disorder associated with cerebral thrombosis (acute phase).
OZAGREL HYDROCHLORIDE contains Ozagrel Hydrochloride. Ozagrel Hydrochloride inhibits thromboxane synthetase, thereby suppressing thromboxane A2 production, enhances prostacyclin production, corrects abnormalities in the balance of those two products, and decreases platelet aggregation.
OZAGREL HYDROCHLORIDE should be administered to patients only in a hospital setting by an experienced healthcare professional. OZAGREL HYDROCHLORIDE may cause certain common side effects, including injection site reactions, rash, erythema (reddening of the skin), asthma attacks, itching, falling blood pressure, anaemia, fever, headache, respiratory distress, cold feeling, the feeling of discomfort, loss of appetite, liver dysfunction, jaundice, fever, chills and decreased urine output, and subcutaneous bleeding. Most of these side effects usually go away on their own. If you develop any other serious side effects, such as vision problems while using OZAGREL HYDROCHLORIDE, consult your doctor immediately.
Before taking OZAGREL HYDROCHLORIDE, let your doctor know about all your medical conditions (especially if you have bleeding disorders), sensitivities (allergic reactions to any medicines or food), and all medications (over-the-counter medicines and dietary supplements as well as other prescription medicines) you are using. Also, inform your doctor if you are pregnant, planning pregnancy, or breastfeeding before receiving OZAGREL HYDROCHLORIDE.
Uses of OZAGREL HYDROCHLORIDE
Medicinal Benefits
OZAGREL HYDROCHLORIDE contains Ozagrel Hydrochloride, which belongs to a class of selective thromboxane A2 synthase inhibitors. Ozagrel Hydrochloride inhibits thromboxane synthetase, thereby suppressing thromboxane A2 production, enhances prostacyclin production, corrects abnormalities in the balance of those two products, and decreases platelet aggregation. Thus, it helps improve cerebrovascular spasms and associated symptoms of cerebral ischemia after surgery for subarachnoid haemorrhage and movement disorder associated with cerebral thrombosis (acute phase).
Directions for Use
Storage
Side Effects of OZAGREL HYDROCHLORIDE
- Feeling or being unwell
- Rash or itching
- Erythema (reddening of the skin)
- Asthma attacks
- Falling of blood pressure
- Anaemia (less red blood cells)
- Fever
- Headache
- Respiratory distress
- Cold feeling
- Feeling of discomfort
- Loss of appetite
- Liver dysfunction
- Jaundice
- Fever
- Chills
- Decreased urine output
- Subcutaneous bleeding
In-Depth Precautions and Warning
Drug Warnings
Before taking OZAGREL HYDROCHLORIDE, tell your doctor If you have previously experienced any allergic reactions to any medicines or foods. If you are pregnant or breastfeeding, have low blood pressure, or have any bleeding disorders, inform your doctor before taking OZAGREL HYDROCHLORIDE. Also, inform your doctor if you are taking any other medications. Since some medications (including OTC, dietary and prescription) may interact with one another, enhancing or decreasing therapeutic benefits.
Drug Interactions
Drug-Drug Interactions: OZAGREL HYDROCHLORIDE may interact with antiplatelet drugs or anticoagulants (e.g. heparin, warfarin)
Drug-Food Interactions: No interaction found/established.
Drug-Disease Interactions: Inform your doctor if you are suffering from low blood pressure and active major bleeding.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionThe interaction of alcohol with OZAGREL HYDROCHLORIDE is unknown. However, as a precautionary measure, it is advisable not to take or limit alcohol.
Pregnancy
cautionThere are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
cautionInform the doctor if you are breastfeeding. A decision should be made whether to discontinue nursing or the medicine, considering the importance of the medicine to the mother.
Driving
cautionIt is not known whether OZAGREL HYDROCHLORIDE alters the ability to drive, so do not drive or operate machinery if you experience any symptoms that affect your ability to concentrate and react.
Liver
cautionLimited information was available about using OZAGREL HYDROCHLORIDE in patients with liver disease. Inform your doctor before receiving OZAGREL HYDROCHLORIDE if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
cautionLimited information was available about using OZAGREL HYDROCHLORIDE in patients with kidney disease. Inform your doctor before receiving OZAGREL HYDROCHLORIDE if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.
Children
consult your doctorThere was limited information about the usage of OZAGREL HYDROCHLORIDE in children. Please seek medical advice.
Habit Forming
Diet & Lifestyle Advise
- Discuss with your doctor about the preferred exercises to do based on your health condition.
- Stay hydrated and consume plenty of fluids. Fluids are necessary to maintain blood flow in your body.
- Consume fresh fruits and vegetables. Consult a dietitian and prepare a diet plan. Eating healthy can help you to recover faster.
- Make no dietary changes without first consulting your doctor.
- You should avoid alcohol because it increases the risk of bleeding.
- Maintain a healthy cholesterol and triglyceride level.
- Maintain a healthy weight and exercise routine to keep your heart healthy.
Special Advise
- OZAGREL HYDROCHLORIDE should be taken under strict medical supervision.
- Keep all appointments with your doctor and the laboratory. The doctor will regularly monitor your condition while taking OZAGREL HYDROCHLORIDE.
Patients Concern
Disease/Condition Glossary
Cerebral ischemia: Cerebral ischemia is a condition in which blood flow to the brain is decreased, resulting in oxygen deprivation and potentially permanent brain damage.
Cerebral thrombosis: Cerebral thrombosis, often known as Cerebral venous sinus thrombosis (CVST) occurs when a blood clot forms in the brain's venous sinuses. This prevents blood from draining out of the brain.
FAQs
OZAGREL HYDROCHLORIDE is used to treat Cerebral ischemia and Acute Cerebral thrombosis.
OZAGREL HYDROCHLORIDE contains Ozagrel Hydrochloride. Ozagrel Hydrochloride inhibits thromboxane synthetase, thereby suppressing thromboxane A2 production, enhances prostacyclin production, corrects abnormalities in the balance of those two products, and decreases platelet aggregation.
Yes, OZAGREL HYDROCHLORIDE raises the possibility of bleeding. Always exercise caution when engaging in activities that could result in an injury or bleeding. Notify your doctor right away if you notice any unusual bruises or bleeding.
To determine blood clotting time, tests such as platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR (international normalised ratio) are utilised.
Caution should be exercised while using OZAGREL HYDROCHLORIDE in patients with low blood pressure. Since OZAGREL HYDROCHLORIDE may cause falling blood pressure, let your doctor know if you suffer from low blood pressure. In that case, your doctor will monitor your blood pressure readings regularly.
