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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Sep 30, 2024 | 4:52 PM IST

STROZAGEL 80MG INJECTION is usually used to improve cerebrovascular spasms and associated symptoms of cerebral ischemia after surgery for subarachnoid haemorrhage and movement disorder associated with cerebral thrombosis (acute phase). It contains Ozagrel Hydrochloride, which inhibits thromboxane synthetase, thereby suppressing thromboxane A2 production. It also enhances prostacyclin production, corrects abnormalities in the balance of those two products, and decreases platelet aggregation.

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Prescription drug

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Prescription drug
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Synonym

OZAGREL

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About STROZAGEL 80MG INJECTION

STROZAGEL 80MG INJECTION belongs to a class of selective thromboxane A2 synthase inhibitors. It is usually used to improve cerebrovascular spasms and associated symptoms of cerebral ischemia after surgery for subarachnoid haemorrhage and movement disorder associated with cerebral thrombosis (acute phase).

STROZAGEL 80MG INJECTION contains Ozagrel Hydrochloride. Ozagrel Hydrochloride inhibits thromboxane synthetase, thereby suppressing thromboxane A2 production, enhances prostacyclin production, corrects abnormalities in the balance of those two products, and decreases platelet aggregation.

STROZAGEL 80MG INJECTION should be administered to patients only in a hospital setting by an experienced healthcare professional. STROZAGEL 80MG INJECTION may cause certain common side effects, including injection site reactions, rash, erythema (reddening of the skin), asthma attacks, itching, falling blood pressure, anaemia, fever, headache, respiratory distress, cold feeling, the feeling of discomfort, loss of appetite, liver dysfunction, jaundice, fever, chills and decreased urine output, and subcutaneous bleeding. Most of these side effects usually go away on their own. If you develop any other serious side effects, such as vision problems while using STROZAGEL 80MG INJECTION, consult your doctor immediately.

Before taking STROZAGEL 80MG INJECTION, let your doctor know about all your medical conditions (especially if you have bleeding disorders), sensitivities (allergic reactions to any medicines or food), and all medications (over-the-counter medicines and dietary supplements as well as other prescription medicines) you are using. Also, inform your doctor if you are pregnant, planning pregnancy, or breastfeeding before receiving STROZAGEL 80MG INJECTION.

Uses of STROZAGEL 80MG INJECTION

Treatment of Cerebral ischemia and Acute Cerebral thrombosis

Medicinal Benefits

STROZAGEL 80MG INJECTION contains Ozagrel Hydrochloride, which belongs to a class of selective thromboxane A2 synthase inhibitors. Ozagrel Hydrochloride inhibits thromboxane synthetase, thereby suppressing thromboxane A2 production, enhances prostacyclin production, corrects abnormalities in the balance of those two products, and decreases platelet aggregation. Thus, it helps improve cerebrovascular spasms and associated symptoms of cerebral ischemia after surgery for subarachnoid haemorrhage and movement disorder associated with cerebral thrombosis (acute phase).

Directions for Use

A healthcare professional will administer STROZAGEL 80MG INJECTION. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of STROZAGEL 80MG INJECTION

  • Feeling or being unwell
  • Rash or itching
  • Erythema (reddening of the skin)
  • Asthma attacks
  • Falling of blood pressure
  • Anaemia (less red blood cells)
  • Fever
  • Headache
  • Respiratory distress
  • Cold feeling
  • Feeling of discomfort
  • Loss of appetite
  • Liver dysfunction
  • Jaundice
  • Fever
  • Chills
  • Decreased urine output
  • Subcutaneous bleeding

Drug Warnings

Before taking STROZAGEL 80MG INJECTION, tell your doctor If you have previously experienced any allergic reactions to any medicines or foods. If you are pregnant or breastfeeding, have low blood pressure, or have any bleeding disorders, inform your doctor before taking STROZAGEL 80MG INJECTION. Also, inform your doctor if you are taking any other medications. Since some medications (including OTC, dietary and prescription) may interact with one another, enhancing or decreasing therapeutic benefits.

Drug Interactions

Drug-Drug Interactions: STROZAGEL 80MG INJECTION may interact with antiplatelet drugs or anticoagulants (e.g. heparin, warfarin)

Drug-Food Interactions: No interaction found/established.

Drug-Disease Interactions: Inform your doctor if you are suffering from low blood pressure and active major bleeding.

Drug-Drug Interactions Checker List

  • HEPARIN
  • WARFARIN

Habit Forming

No

Diet & Lifestyle Advise

  • Discuss with your doctor about the preferred exercises to do based on your health condition.
  • Stay hydrated and consume plenty of fluids. Fluids are necessary to maintain blood flow in your body.
  • Consume fresh fruits and vegetables. Consult a dietitian and prepare a diet plan. Eating healthy can help you to recover faster.
  • Make no dietary changes without first consulting your doctor.
  • You should avoid alcohol because it increases the risk of bleeding.
  • Maintain a healthy cholesterol and triglyceride level.
  • Maintain a healthy weight and exercise routine to keep your heart healthy.

Special Advise

  • STROZAGEL 80MG INJECTION should be taken under strict medical supervision.
  • Keep all appointments with your doctor and the laboratory. The doctor will regularly monitor your condition while taking STROZAGEL 80MG INJECTION.

Disease/Condition Glossary

Cerebral ischemia: Cerebral ischemia is a condition in which blood flow to the brain is decreased, resulting in oxygen deprivation and potentially permanent brain damage.

Cerebral thrombosis: Cerebral thrombosis, often known as Cerebral venous sinus thrombosis (CVST) occurs when a blood clot forms in the brain's venous sinuses. This prevents blood from draining out of the brain.

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Alcohol

Caution

The interaction of alcohol with STROZAGEL 80MG INJECTION is unknown. However, as a precautionary measure, it is advisable not to take or limit alcohol.

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Pregnancy

Caution

There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Inform the doctor if you are breastfeeding. A decision should be made whether to discontinue nursing or the medicine, considering the importance of the medicine to the mother.

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Driving

Caution

It is not known whether STROZAGEL 80MG INJECTION alters the ability to drive, so do not drive or operate machinery if you experience any symptoms that affect your ability to concentrate and react.

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Liver

Caution

Limited information was available about using STROZAGEL 80MG INJECTION in patients with liver disease. Inform your doctor before receiving STROZAGEL 80MG INJECTION if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Limited information was available about using STROZAGEL 80MG INJECTION in patients with kidney disease. Inform your doctor before receiving STROZAGEL 80MG INJECTION if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Consult your doctor

There was limited information about the usage of STROZAGEL 80MG INJECTION in children. Please seek medical advice.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - STR0088

Author Details

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FAQs

STROZAGEL 80MG INJECTION is used to treat Cerebral ischemia and Acute Cerebral thrombosis.
STROZAGEL 80MG INJECTION contains Ozagrel Hydrochloride. Ozagrel Hydrochloride inhibits thromboxane synthetase, thereby suppressing thromboxane A2 production, enhances prostacyclin production, corrects abnormalities in the balance of those two products, and decreases platelet aggregation.
Yes, STROZAGEL 80MG INJECTION raises the possibility of bleeding. Always exercise caution when engaging in activities that could result in an injury or bleeding. Notify your doctor right away if you notice any unusual bruises or bleeding.
To determine blood clotting time, tests such as platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR (international normalised ratio) are utilised.
Caution should be exercised while using STROZAGEL 80MG INJECTION in patients with low blood pressure. Since STROZAGEL 80MG INJECTION may cause falling blood pressure, let your doctor know if you suffer from low blood pressure. In that case, your doctor will monitor your blood pressure readings regularly.

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