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Doxifluridine

About Doxifluridine

It is a second-generation nucleotide analogue prodrug used as a cytostatic agent in chemotherapy, especially for stomach, colon, rectum, breast, uterine, cervix and bladder cancer.

Doxifluridine contains doxifluridine, which is used to improve the selectivity and efficacy of cancer therapy by targeting certain abnormal markers overexpressed by cancer cells but not found in normal tissues.

To treat your condition effectively, continue using Doxifluridine for as long as your doctor has prescribed it. The most frequently observed side effects are rash, eczema, hives, diarrhoea, and appetite loss. Speak with your pharmacist or doctor if you experience any of these symptoms.

Before taking Doxifluridine, inform your doctor about all your allergic or hypersensitivity reactions to medicines or food. Chemotherapy may cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant or get pregnant while undergoing therapy and for several months after the treatment. Using effective contraceptive methods is recommended while on therapy. Contact your doctor immediately if you or your partner becomes pregnant while undergoing therapy. Breastfeeding is usually not advised during this treatment. Alcohol should be avoided during treatment with this medicine. Safety and effectiveness in children have not been established.

Uses of Doxifluridine

A prodrug in chemotherapy (adjuvant treatment of several cancers)

Medicinal Benefits

Doxifluridine contains doxifluridine, a second-generation nucleotide analogue prodrug used as a cytostatic agent in chemotherapy, especially for stomach, colon, rectum, breast, uterine, cervix and bladder cancer. Prodrugs have been used to improve the selectivity and efficacy of cancer therapy by targeting certain abnormal markers overexpressed by cancer cells but not found in normal tissues.

Directions for Use

Doxifluridine should be swallowed as a whole with a glass of water. Do not crush, chew, or break the tablets. The doctor determines the dose and duration based on your health condition.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Doxifluridine

  • Feeing or being unwell
  • Fatigue
  • Hair loss
  • Oral sores
  • Bone marrow suppression
  • Increased risk of infection

Drug Warnings

Before taking Doxifluridine, inform your doctor about all your medical conditions, sensitivities, and medications you are using. Doxifluridine is not suggested during pregnancy since there is insufficient evidence on how it may impact a growing infant, so you should not become pregnant or father a child while on this medication. Effective birth control is required throughout treatment and for a certain time as the doctor directs. You should not breastfeed while taking this medication for a certain time, as directed by the doctor. Unless the doctor suggests, do not use other medicine, including herbal or vitamin supplements.

Drug Interactions

Drug-Drug Interactions: No interactions found or established.

Drug-Food Interactions: No interactions found or established.

Drug-Disease Interactions: No interactions found or established.

Drug-Drug Interactions Checker List:

Safety Advice

  • Safety Warning

    Alcohol

    caution

    Avoid alcohol consumption while on treatment with Doxifluridine.

  • Safety Warning

    Pregnancy

    caution

    Caution as advised. If you are pregnant, inform your doctor before taking this medicine.

  • Safety Warning

    Breast Feeding

    caution

    Caution as advised. If you are breastfeeding, inform your doctor before taking this medicine.

  • Safety Warning

    Driving

    caution

    Doxifluridine may cause fatigue (feeling overtired), impacting the ability to drive or use machines.

  • Safety Warning

    Liver

    caution

    Limited information was available about using Doxifluridine in patients with liver disease. Inform your doctor before receiving Doxifluridine if you have a history of liver diseases. Your doctor will prescribe only if the benefits outweigh the risks.

  • Safety Warning

    Kidney

    caution

    Limited information was available about using Doxifluridine in patients with kidney disease. Inform your doctor before receiving Doxifluridine if you have a history of kidney diseases. Your doctor will prescribe only if the benefits outweigh the risks.

  • Safety Warning

    Children

    consult your doctor

    Limited information is available. Please consult your doctor.

Habit Forming

No

Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Special Advise

  • Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to Doxifluridine.
  • Pregnancy testing is recommended prior to starting treatment with Doxifluridine.

Patients Concern

Disease/Condition Glossary

Cancer: Cancer is a genetic change in which the body's cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). Types of cancer include blood, lung, breast, etc. Cancer growth can be prevented by chemotherapy, radiation, and stem cell therapy.

FAQs

Doxifluridine is used as a prodrug in chemotherapy (adjuvant treatment of several cancers).

Doxifluridine contains doxifluridine, which is used to improve the selectivity and efficacy of cancer therapy by targeting certain abnormal markers overexpressed by cancer cells but not found in normal tissues.

While taking Doxifluridine, visit your doctor at all the appointments to ensure treatment works. Regular monitoring of blood and lipid tests and weight checks are required. An effective way of contraception should be used by both men and women while taking Doxifluridine.

Limited information is available. Discuss the risks of taking this medication with your doctor.

Available Medicines for

Doxifluridine

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