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Cefoperazone+tazobactam

About Cefoperazone+tazobactam

Cefoperazone+tazobactam belongs to the group of medicines called antibiotics used to treat bacterial infections such as gynaecological infections, urinary tract infections, post-operative infections, meningitis (inflammation of brain and spinal cord), biliary infections, septicaemia, infections in immune-compromised patients, skin and soft tissue infections, and bone and joint infections.

Cefoperazone+tazobactam contains Cefoperazone and Tazobactam. Cefoperazone kills bacteria by inhibiting nucleopeptide synthesis in the bacterial cell wall. Tazobactam reduces bacterial resistance and enhances the activity of Cefoperazone against bacteria. Together, Cefoperazone+tazobactam helps to treat bacterial infections.

In some cases, Cefoperazone+tazobactam may cause side effects such as pain and inflammation at the site of injection, nausea, vomiting, and indigestion. These side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

Consult the doctor if you are pregnant or breastfeeding. The safety and efficacy of Cefoperazone+tazobactam in children below 12 years has not been established. Keep the doctor informed about your health condition and medications to rule out any unpleasant side effects/interactions.

Uses of Cefoperazone+tazobactam

Treatment of Bacterial infections

Medicinal Benefits

Cefoperazone+tazobactam belongs to the group of medicines called antibiotics used to treat bacterial infections such as gynaecological infections, urinary tract infections, post-operative infections, meningitis (inflammation of brain and spinal cord), biliary infections, septicaemia, infections in immune-compromised patients, skin and soft tissue infections, bone and joint infections, and gonorrhoea. Cefoperazone+tazobactam contains Cefoperazone (cephalosporin antibiotic) and Tazobactam (beta-lactamase inhibitor). Cefoperazone kills the bacteria by inhibiting nucleopeptide synthesis in the bacterial cell wall. Tazobactam reduces bacterial resistance and enhances the activity of Cefoperazone against bacteria. Together, Cefoperazone+tazobactam helps to treat bacterial infections.

Directions for Use

Cefoperazone+tazobactam will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cefoperazone+tazobactam

  • Pain and inflammation at the site of injection
  • Nausea
  • Vomiting
  • Indigestion

Drug Warnings

Do not receive Cefoperazone+tazobactam if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. The safety and efficacy of Cefoperazone+tazobactam in children below 12 years has not been established. Let the doctor know if you take prescription/non-prescription medicines, including supplements or herbal products.

Drug Interactions

Drug-Drug Interactions: No interactions found/established.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: No interactions found/established.

Drug-Drug Interactions Checker List:

Safety Advice

  • Safety Warning

    Alcohol

    caution

    Avoid/limit the consumption of alcohol.

  • Safety Warning

    Pregnancy

    caution

    If you are pregnant or planning pregnancy, inform your doctor before receiving Cefoperazone+tazobactam. Cefoperazone+tazobactam should be used during pregnancy only if clearly needed.

  • Safety Warning

    Breast Feeding

    caution

    If you are breastfeeding, inform your doctor before receiving Cefoperazone+tazobactam. Cefoperazone+tazobactam should be used with caution in breastfeeding women.

  • Safety Warning

    Driving

    consult your doctor

    It is not known if Cefoperazone+tazobactam affects your ability to drive. Drive or operate machinery only if you are alert.

  • Safety Warning

    Liver

    consult your doctor

    If you have a history of liver disease, inform your doctor before receiving Cefoperazone+tazobactam.

  • Safety Warning

    Kidney

    consult your doctor

    If you have a history of kidney disease, inform your doctor before receiving Cefoperazone+tazobactam.

  • Safety Warning

    Children

    caution

    The safety and effectiveness of Cefoperazone+tazobactam in children below 12 years has not been established.

Habit Forming

No

Diet & Lifestyle Advise

  • Include whole grains, fruits, and vegetables in your diet. 
  • Taking probiotics after antibiotics and eating high-fibre and prebiotic foods may help reduce side effects and support digestion.
  • Exercising regularly helps in improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress.
  • Avoid processed and fried food.

Patients Concern

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Harmful bacteria produce chemicals known as toxins, which can damage tissue and cause sickness. Generalized symptoms of bacterial infection include fever, chills, and fatigue. Anyone can become infected with a bacterial infection. However, people with a weak immune system or taking immunosuppressive medicines are more prone to bacterial infection.

FAQs

Cefoperazone+tazobactam is used to treat Bacterial infections.

Cefoperazone+tazobactam works by inhibiting nucleopeptide synthesis in the bacterial cell wall. It also helps decrease bacterial resistance.

Pseudomembranous colitis, a severe inflammation of the inner lining of the large intestine, has been reported using cephalosporin antibiotics. Therefore, it is necessary to consider its diagnosis in patients who develop diarrhoea associated with antibiotic use.

Dyspepsia (indigestion) might be a side effect of Cefoperazone+tazobactam. To prevent indigestion, eat smaller, more frequent meals and chew your food slowly and thoroughly. However, if the condition persists or worsens, consult the doctor.

Cefoperazone+tazobactam may cause common side effects such as pain and inflammation at the site of injection, nausea, vomiting, and indigestion. These side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

You should take Cefoperazone+tazobactam for as long as your doctor prescribes it, depending on the type and severity of your infection. It is typically taken for 4 to 14 days. If your symptoms do not improve or get worse, please contact your doctor immediately.

The use of Cefoperazone+tazobactam does not typically cause diarrhoea. However, if you experience diarrhoea unusually or have concerns, please consult your doctor.

Cefoperazone+tazobactam usually starts working within a few hours after taking it. However, the full effect may take a few days, depending on the infection and how your body responds to the medication. Always follow your doctor's instructions and let them know if you do not see any improvement in your symptoms.

If you don't get better after using Cefoperazone+tazobactam, it could be because the infection is resistant to the medication or there might be another underlying cause. Let your doctor know so they can adjust your dose or treatment, check for antibiotic resistance, or look into other possible causes. Always follow your doctor's advice and never stop the medication without consulting them first.

No, you should not stop taking Cefoperazone+tazobactam just because you feel better. It's important to finish the entire course of antibiotics as prescribed by your doctor, even if you start feeling better. Stopping early could cause the infection to return or make the bacteria resistant to the medication.

Available Medicines for

Cefoperazone+tazobactam

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