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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Viropil Tablet is used to treat HIV-1 infection. It works by increasing the immune cells that help fight infections in the body and interfering with the working of certain enzymes which are necessary for the reproduction of the virus; thereby decreasing the amount of HIV in the blood. In some cases, this medicine may cause side effects such as fatigue, diarrhoea, headache, pain, fever, cough, and insomnia. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions. Practise safe sex and other necessary precautions as this medicine does not prevent the spread of HIV infection.
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Manufacturer/Marketer

Emcure Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Viropil Tablet

Viropil Tablet belongs to a group of antiretroviral medicines indicated for the treatment of HIV-1 infection in adults and children weighing at least 35kgs. HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses.
 
Viropil Tablet contains Dolutegravir (integrase inhibitor), Lamivudine (nucleoside reverse transcriptase inhibitor), and Tenofovir disoproxil fumarate (nucleotide reverse transcriptase inhibitor). Dolutegravir increases the immune cells that help fight infections in the body and decreases the amount of HIV in the blood. Lamivudine and Tenofovir disoproxil fumarate work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, Viropil Tablet helps in treating HIV infection.
 
You are advised to take Viropil Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as fatigue, diarrhoea, headache, pain, rash, depression, fever, cough, and insomnia. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Practise safe sex and other necessary precautions as Viropil Tablet does not prevent the spread of HIV infection. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking Viropil Tablet . Viropil Tablet may cause dizziness, so drive with caution. Viropil Tablet is not recommended for children weighing below 35 kg. Keep your doctor informed about your health condition and the medicines you are taking to prevent any side effects/interactions.

Uses of Viropil Tablet

Treatment of HIV infection

Medicinal Benefits

Viropil Tablet is a combination of three drugs, namely: Dolutegravir, Lamivudine and Tenofovir disoproxil fumarate. Viropil Tablet belongs to a group of antiretroviral medicines indicated for the treatment of HIV-1 infection in adults and children weighing at least 35kgs. Dolutegravir is an integrase inhibitor that increases the immune cells that help fight infections in the body and decreases the amount of HIV in the blood. Lamivudine is a nucleoside reverse transcriptase inhibitor, and Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor. They work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, Viropil Tablet helps in treating HIV infection.

Directions for Use

Swallow Viropil Tablet as a whole with water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Viropil Tablet

  • Fatigue
  • Diarrhoea
  • Headache
  • Pain
  • Rash
  • Depression
  • Fever
  • Cough
  • Insomnia 

Drug Warnings

Do not take Viropil Tablet if you are allergic to any of its components. Inform your doctor if you have a history of hepatitis B or C infection, bone problems, pancreas disorder, kidney/liver problems, or if you are taking dofetilide (anti-arrhythmic agent). Practise safe sex and other necessary precautions as Viropil Tablet does not prevent the spread of HIV infection. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking Viropil Tablet . Viropil Tablet may cause dizziness, so drive with caution. Viropil Tablet is not recommended for children weighing below 35 kg. Talk to your doctor immediately if you notice any signs or symptoms of infection or inflammation.

Drug Interactions

Drug-Drug Interactions: Viropil Tablet may interact with an anti-arrhythmic agent (dofetilide)

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have hepatitis B, pancreatitis, bone problems, kidney or liver problems.

Drug-Drug Interactions Checker List

  • DOFETILIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injections or drug equipment.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruits as it helps to boost the immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or by doing whatever makes you happy.

Special Advise

  • Get HIV test done for at least every 3 months.
  • Regular kidney and liver function tests, bone mineral density test while taking Viropil Tablet is advised. 
  • Viropil Tablet might affect laboratory test results; inform the person doing the tests that you are taking Viropil Tablet .
  • Regularly get blood and urine tests done while taking Viropil Tablet .

Disease/Condition Glossary

HIV infection: HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating with antiretroviral drugs. 

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Alcohol

Caution

It is not known whether Viropil Tablet interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

Viropil Tablet might cause embryo-fetal toxicity when taken at the time of conception and during early pregnancy. Please consult your doctor if you have any concerns regarding this.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Viropil Tablet . Consult your doctor if you have any concerns regarding this.

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Driving

Caution

Viropil Tablet may cause dizziness. So, drive or operating machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Viropil Tablet is not recommended for children weighing below 35kgs. Consult your doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - VIR0105

Author Details

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FAQs

Viropil Tablet is used to treat HIV infection.
Viropil Tablet contains Dolutegravir, Lamivudine, and Tenofovir disoproxil fumarate. Dolutegravir increases the immune cells that help fight infections in the body and decreases the amount of HIV in the blood. Lamivudine and Tenofovir disoproxil fumarate work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, Viropil Tablet helps in treating HIV infection.
Do not stop taking Viropil Tablet without consulting your doctor as it may reduce the effectiveness of anti-HIV therapy. Continue taking Viropil Tablet for as long as your doctor has prescribed it to you to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Viropil Tablet .
Viropil Tablet might cause lactic acidosis (excess of lactic acid in the blood), a rare but severe side effect. Consult a doctor immediately if you experience stomach pain, vomiting, nausea, drowsiness, and deep rapid breathing, as these could be the signs of lactic acidosis.
Viropil Tablet may cause bone problems such as bone pain, softening or thinning of bone which might lead to bone fractures. A regular bone density test is advised while taking Viropil Tablet .
Antacids, laxatives, or other medicines containing magnesium, aluminium or buffered medicines (medicines used to neutralise stomach acids) should be taken 2 hours before and 6 hours after taking Viropil Tablet . Consult your doctor if you have any concerns.
You can take iron or calcium supplements with Viropil Tablet if you have taken Viropil Tablet with food. If you haven’t taken Viropil Tablet with food, take Viropil Tablet 2 hours before or 6 hours after taking iron or calcium supplements. Consult your doctor if you have any concerns.

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