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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:18 PM IST

Ulifosep 100000Iu Inj is used to treat severe sepsis (a condition triggered by an extreme immune system response to infections) and acute pancreatitis (inflammation of the pancreas). It contains Ulinastatin, an active ingredient belonging to the protease inhibitor class of drugs. It works by inhibiting serine proteases, which help prevent organ dysfunction.

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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Glenmark Pharmaceuticals Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Ulifosep 100000Iu Inj

Ulifosep 100000Iu Inj belongs to the class of medicine called protease inhibitors. It is used in the treatment of severe sepsis (a condition triggered by an extreme response of the immune system to infections) and acute pancreatitis (inflammation of the pancreas).

Ulifosep 100000Iu Inj contains Ulinastatin as an active ingredient, which belongs to the protease inhibitor class of drugs. It works by inhibiting serine proteases, including trypsin, chymotrypsin, kallikrein, plasmin, thrombin, factors IXa, Xa, XIa, and XlIa. This helps prevent organ dysfunction.

Ulifosep 100000Iu Inj may cause certain side effects, such as nausea, vomiting, headache, skin rash, itching, diarrhoea, allergic reactions and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. A trained healthcare professional will administer it. Do not self-administer.

Ulifosep 100000Iu Inj should be avoided if you are allergic to it or any other components present in it. Before administration, inform your doctor if you have liver/kidney disease, cardiac disorders, bleeding disorders or respiratory conditions. It is unknown whether Ulifosep 100000Iu Inj is suitable for use in pregnant and breastfeeding mothers. Hence, inform your doctor if you are pregnant, are planning to become pregnant or are breastfeeding beforehand.

Uses of Ulifosep 100000Iu Inj

Treatment of Severe Sepsis and Acute Pancreatitis

Medicinal Benefits

Ulifosep 100000Iu Inj contains Ulinastatin as an active ingredient used in the treatment of sepsis and pancreatitis. It belongs to the protease inhibitor class of drugs that works by activating and inhibiting serine proteases, including trypsin, chymotrypsin, kallikrein, plasmin, granulocyte elastase, cathepsin, thrombin, and factors IXa, Xa, XIa, and XlIa. This reduces the pro-inflammatory response due to disease and helps prevent organ dysfunction.

Directions for Use

Ulifosep 100000Iu Inj will be administered by a trained healthcare professional. Do not self-administer. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ulifosep 100000Iu Inj

  • Nausea
  • Skin rash
  • Stomach upset
  • Headache
  • Vomiting
  • Itching
  • Diarrhoea
  • Pain at the site of injection
  • Allergic reactions

Drug Warnings

Ulifosep 100000Iu Inj should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease, cardiac disorders, bleeding disorders or respiratory conditions. Ulifosep 100000Iu Inj should be avoided in children as safety and efficacy are not established. It is unknown whether Ulifosep 100000Iu Inj is suitable for use in pregnant and breastfeeding mothers. Hence, inform your doctor if you are pregnant, are planning to become pregnant or are breastfeeding beforehand.

Drug Interactions

Drug-Drug Interactions: No interactions found.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform your doctor if you have kidney or liver disease, blood disorders, and pulmonary disorders before receiving Ulifosep 100000Iu Inj.

Habit Forming

No

Diet & Lifestyle Advise

  • Cut back on fried foods and animal fats. Eat lean meats, healthy fats, fruits, vegetables and whole-grain foods. Avoid lactose (milk, ice cream, cheese, yoghurt); fruits like mangoes, apples and plums; legumes; corn syrup, sweeteners; wheat-based bread, cashews and pistachios)
  • Avoid taking Ulifosep 100000Iu Inj with alcohol as there may be an interaction.
  • Stay hydrated by drinking plenty of water, as dehydration is often seen after Ulifosep 100000Iu Inj.
  • Hypnotherapy and meditation have also proven very effective in relieving symptoms of IBS and other psychosomatic gastric disorders. Check out such holistic treatments for the same.  
  • Yoga has also proven very effective in controlling many abdominal diseases and promoting good health and digestion. Try to do yoga at least thrice a week.

Special Advise

  • Inform your doctor immediately if you accidentally take an extra dose of Ulifosep 100000Iu Inj. Common overdose symptoms can include anxiety, hives, shortness of breath, drowsiness, blurred vision, difficulty swallowing, and feeling hyper, agitated or nervous.
  • Please know that your doctor may order blood tests to check your tolerance and need a Ulifosep 100000Iu Inj.

Disease/Condition Glossary

Sepsis: It is a life-threatening illness caused by the body's response to an infection. Sepsis occurs when chemicals released in the blood to fight infection trigger inflammation in the body. This may lead to a cascade of changes that damage multiple organ systems, leading them to fail, sometimes even resulting in death. Symptoms may include low blood pressure, chills, dizziness, fatigue, fever, flushing, low body temperature, shivering, fast breathing, shortness of breath, etc.

Pancreatitis: Pancreas play an important role in the digestion of food. It produces enzymes which help in the breakdown of food and absorption of nutrients. Swelling of the pancreas is referred to as pancreatitis. It may be of sudden onset, or it may develop as a chronic condition. Symptoms may include nausea, vomiting and abdominal pain. Alcoholics are more prone to this condition.

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Alcohol

Unsafe

Avoid alcohol consumption during the treatment as it can increase the adverse effects and worsen the condition.

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Pregnancy

Caution

Limited data is available on the effect of Ulifosep 100000Iu Inj in pregnancy. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Ulifosep 100000Iu Inj. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited data is available on the effect of Ulifosep 100000Iu Inj on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Ulifosep 100000Iu Inj. You should not breastfeed while on treatment with Ulifosep 100000Iu Inj.

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Driving

Caution

Ulifosep 100000Iu Inj will be administered in the hospital setting. Hence, avoid driving.

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Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Ulifosep 100000Iu Inj. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Ulifosep 100000Iu Inj. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Children

Unsafe

Ulifosep 100000Iu Inj is not recommended for use in children as the safety and efficacy are not established.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Other Info - ULI0011

FAQs

Ulifosep 100000Iu Inj is used to treat Severe Sepsis and Acute Pancreatitis.
Ulifosep 100000Iu Inj contains Ulinastatin, which works by inhibiting serine proteases, including trypsin, chymotrypsin, kallikrein, plasmin, thrombin, factors IXa, Xa, XIa, and XlIa. This helps prevent organ dysfunction.
Ulifosep 100000Iu Inj is safe when used as per the dose and duration advised by a doctor.
Ulifosep 100000Iu Inj causes side effects such as nausea, skin rash stomach upset, diarrhoea, itching, vomiting, pain at site of injection, and headache. Most of these are temporary and do not require any medical attention, as they will gradually reduce over time. Please, contact a doctor if these persist for longer durations.

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