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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:18 PM IST

Ulitryp 100000IU Injection 4 ml is used to treat severe sepsis (a condition triggered by an extreme immune system response to infections) and acute pancreatitis (inflammation of the pancreas). It contains Ulinastatin, an active ingredient belonging to the protease inhibitor class of drugs. It works by inhibiting serine proteases, which help prevent organ dysfunction.

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Manufacturer/Marketer

Bharat Serums and Vaccines Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Ulitryp 100000IU Injection 4 ml

Ulitryp 100000IU Injection 4 ml belongs to the class of medicine called protease inhibitors. It is used in the treatment of severe sepsis (a condition triggered by an extreme response of the immune system to infections) and acute pancreatitis (inflammation of the pancreas).

Ulitryp 100000IU Injection 4 ml contains Ulinastatin as an active ingredient, which belongs to the protease inhibitor class of drugs. It works by inhibiting serine proteases, including trypsin, chymotrypsin, kallikrein, plasmin, thrombin, factors IXa, Xa, XIa, and XlIa. This helps prevent organ dysfunction.

Ulitryp 100000IU Injection 4 ml may cause certain side effects, such as nausea, vomiting, headache, skin rash, itching, diarrhoea, allergic reactions and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. A trained healthcare professional will administer it. Do not self-administer.

Ulitryp 100000IU Injection 4 ml should be avoided if you are allergic to it or any other components present in it. Before administration, inform your doctor if you have liver/kidney disease, cardiac disorders, bleeding disorders or respiratory conditions. It is unknown whether Ulitryp 100000IU Injection 4 ml is suitable for use in pregnant and breastfeeding mothers. Hence, inform your doctor if you are pregnant, are planning to become pregnant or are breastfeeding beforehand.

Uses of Ulitryp 100000IU Injection 4 ml

Treatment of Severe Sepsis and Acute Pancreatitis

Medicinal Benefits

Ulitryp 100000IU Injection 4 ml contains Ulinastatin as an active ingredient used in the treatment of sepsis and pancreatitis. It belongs to the protease inhibitor class of drugs that works by activating and inhibiting serine proteases, including trypsin, chymotrypsin, kallikrein, plasmin, granulocyte elastase, cathepsin, thrombin, and factors IXa, Xa, XIa, and XlIa. This reduces the pro-inflammatory response due to disease and helps prevent organ dysfunction.

Directions for Use

Ulitryp 100000IU Injection 4 ml will be administered by a trained healthcare professional. Do not self-administer. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ulitryp 100000IU Injection 4 ml

  • Nausea
  • Skin rash
  • Stomach upset
  • Headache
  • Vomiting
  • Itching
  • Diarrhoea
  • Pain at the site of injection
  • Allergic reactions

Drug Warnings

Ulitryp 100000IU Injection 4 ml should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease, cardiac disorders, bleeding disorders or respiratory conditions. Ulitryp 100000IU Injection 4 ml should be avoided in children as safety and efficacy are not established. It is unknown whether Ulitryp 100000IU Injection 4 ml is suitable for use in pregnant and breastfeeding mothers. Hence, inform your doctor if you are pregnant, are planning to become pregnant or are breastfeeding beforehand.

Drug Interactions

Drug-Drug Interactions: No interactions found.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform your doctor if you have kidney or liver disease, blood disorders, and pulmonary disorders before receiving Ulitryp 100000IU Injection 4 ml.

Habit Forming

No

Diet & Lifestyle Advise

  • Cut back on fried foods and animal fats. Eat lean meats, healthy fats, fruits, vegetables and whole-grain foods. Avoid lactose (milk, ice cream, cheese, yoghurt); fruits like mangoes, apples and plums; legumes; corn syrup, sweeteners; wheat-based bread, cashews and pistachios)
  • Avoid taking Ulitryp 100000IU Injection 4 ml with alcohol as there may be an interaction.
  • Stay hydrated by drinking plenty of water, as dehydration is often seen after Ulitryp 100000IU Injection 4 ml.
  • Hypnotherapy and meditation have also proven very effective in relieving symptoms of IBS and other psychosomatic gastric disorders. Check out such holistic treatments for the same.  
  • Yoga has also proven very effective in controlling many abdominal diseases and promoting good health and digestion. Try to do yoga at least thrice a week.

Special Advise

  • Inform your doctor immediately if you accidentally take an extra dose of Ulitryp 100000IU Injection 4 ml. Common overdose symptoms can include anxiety, hives, shortness of breath, drowsiness, blurred vision, difficulty swallowing, and feeling hyper, agitated or nervous.
  • Please know that your doctor may order blood tests to check your tolerance and need a Ulitryp 100000IU Injection 4 ml.

Disease/Condition Glossary

Sepsis: It is a life-threatening illness caused by the body's response to an infection. Sepsis occurs when chemicals released in the blood to fight infection trigger inflammation in the body. This may lead to a cascade of changes that damage multiple organ systems, leading them to fail, sometimes even resulting in death. Symptoms may include low blood pressure, chills, dizziness, fatigue, fever, flushing, low body temperature, shivering, fast breathing, shortness of breath, etc.

Pancreatitis: Pancreas play an important role in the digestion of food. It produces enzymes which help in the breakdown of food and absorption of nutrients. Swelling of the pancreas is referred to as pancreatitis. It may be of sudden onset, or it may develop as a chronic condition. Symptoms may include nausea, vomiting and abdominal pain. Alcoholics are more prone to this condition.

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Alcohol

Unsafe

Avoid alcohol consumption during the treatment as it can increase the adverse effects and worsen the condition.

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Pregnancy

Caution

Limited data is available on the effect of Ulitryp 100000IU Injection 4 ml in pregnancy. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Ulitryp 100000IU Injection 4 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited data is available on the effect of Ulitryp 100000IU Injection 4 ml on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Ulitryp 100000IU Injection 4 ml. You should not breastfeed while on treatment with Ulitryp 100000IU Injection 4 ml.

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Driving

Caution

Ulitryp 100000IU Injection 4 ml will be administered in the hospital setting. Hence, avoid driving.

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Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Ulitryp 100000IU Injection 4 ml. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Ulitryp 100000IU Injection 4 ml. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Children

Unsafe

Ulitryp 100000IU Injection 4 ml is not recommended for use in children as the safety and efficacy are not established.

Country of origin

India

Manufacturer/Marketer address

17Th Floor, Hoechst House, Nariman Point, Mumbai 400 021, Maharashtra, India.
Other Info - ULI0019

FAQs

Ulitryp 100000IU Injection 4 ml is used to treat Severe Sepsis and Acute Pancreatitis.
Ulitryp 100000IU Injection 4 ml contains Ulinastatin, which works by inhibiting serine proteases, including trypsin, chymotrypsin, kallikrein, plasmin, thrombin, factors IXa, Xa, XIa, and XlIa. This helps prevent organ dysfunction.
Ulitryp 100000IU Injection 4 ml is safe when used as per the dose and duration advised by a doctor.
Ulitryp 100000IU Injection 4 ml causes side effects such as nausea, skin rash stomach upset, diarrhoea, itching, vomiting, pain at site of injection, and headache. Most of these are temporary and do not require any medical attention, as they will gradually reduce over time. Please, contact a doctor if these persist for longer durations.

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