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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 9:32 AM IST

Tepmetko 225 mg Tablet is primarily used to treat lung cancer. It contains Tepotinib. It works by blocking the abnormal protein, which can cause uncontrolled cell growth and cancer; thus, it slows or stops cancer growth. Tepmetko 225 mg Tablet can cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant or get pregnant while undergoing therapy and for several months after the treatment. Using effective contraceptive methods is recommended while on therapy. Contact your doctor immediately if you or your partner becomes pregnant while undergoing therapy.

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Prescription drug

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Composition :

TEPOTINIB-225MG

Manufacturer/Marketer :

Merck Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Tepmetko 225 mg Tablet

Tepmetko 225 mg Tablet belongs to a class of protein kinase inhibitors primarily used to manage or treat lung cancer that has progressed to other body regions or cannot be removed surgically. Lung cancer is a disease that causes malignant (cancer) cells to grow in lung tissues.

Tepmetko 225 mg Tablet contains Tepotinib. It works by blocking the abnormal protein, which can cause uncontrolled cell growth and cancer; thus, it slows or stops cancer growth.

To treat your condition effectually, continue using Tepmetko 225 mg Tablet for as long as your doctor has prescribed it. The most common adverse reactions are oedema (swelling), fatigue (tiredness), diarrhoea, musculoskeletal pain, dyspnea (shortness of breath), feeling sick (nausea), being sick (vomiting), diarrhoea and QT prolongation. You should talk to your doctor if you persistently experience these side effects.

Inform your doctor if you are allergic to it or have ILD (Interstitial lung disease)/pneumonitis (inflammation in your lung tissues without an infection). Tepmetko 225 mg Tablet can cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant or get pregnant while undergoing therapy and for several months after the treatment. Using effective contraceptive methods is recommended while on therapy with Tepmetko 225 mg Tablet . Contact your doctor immediately if you or your partner becomes pregnant while undergoing therapy. Breastfeeding is usually not advised during this treatment since it is unknown whether this medication passes into breast milk. Alcohol should be avoided during treatment with this medicine. Safety and effectiveness in children have not been established.

Uses of Tepmetko 225 mg Tablet

Treatment of Lung cancer (non-small cell lung cancer)

Medicinal Benefits

Tepmetko 225 mg Tablet contains Tepotinib, which belongs to a class of protein kinase inhibitors primarily used to manage or treat adults with lung cancer that has progressed to other regions of the body or cannot be removed surgically. It works by blocking the abnormal protein, which can cause uncontrolled cell growth and cancer; thus, it slows or stops cancer growth.

Side Effects of Tepmetko 225 mg Tablet

  • Oedema (Swelling)
  • Fatigue (Tiredness)
  • Diarrhea
  • Musculoskeletal pain
  • Dyspnea (Shortness of breath)
  • Feeling sick (Nausea)
  • being sick (Vomiting)
  • Diarrhoea
  • Raised levels of creatinine in blood (a sign of possible kidney problems)
  • Raised levels of alanine aminotransferase, aspartate aminotransferase or alkaline phosphatase in blood (a sign of possible liver problems)
  • Raised levels of amylase or lipase in the blood (a sign of possible digestive problems)
  • Reduced levels of the protein albumin in blood
  • Change in electrical activity of the heart (QT prolongation)

Directions for Use

Tepmetko 225 mg Tablet should be swallowed as a whole with a glass of water. Do not crush, chew, or break the tablets. The doctor determines the dose and duration based on your health condition.

Drug Warnings

Before taking the Tepmetko 225 mg Tablet , inform your doctor about all your medical conditions, sensitivities, and medications you are using. If you are a woman capable of having children, you should use an effective method of contraception during Tepotinib treatment and for at least one week after the last dose. If you are a man, you should use a barrier method of contraception to prevent your partner from becoming pregnant while taking Tepotinib and for at least one week after the last dose. Do not use any other medicine, including herbal or vitamin supplements, unless the doctor suggests.

Therapeutic Class

KINASE INHIBITORS

Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

How Tepmetko 225 mg Tablet Works

Tepmetko 225 mg Tablet contains Tepotinib. It works by blocking the abnormal protein, which can cause uncontrolled cell growth and cancer; thus, it slows or stops cancer growth.

What if I have taken an overdose of Tepmetko 225 mg Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Tepmetko 225 mg Tablet may include gastrointestinal symptoms, musculoskeletal pain, and laboratory abnormalities. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.
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Alcohol

Caution

Avoid alcohol consumption while on treatment with Tepmetko 225 mg Tablet .

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Pregnancy

Unsafe

Tepmetko 225 mg Tablet should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.

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Breast Feeding

Caution

Tepmetko 225 mg Tablet should not be used in breastfeeding. Discuss with your doctor if you have any concerns.

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Driving

Caution

Tepmetko 225 mg Tablet does not influence the ability to drive or use machines. However, go only if you are alert, as the Tepmetko 225 mg Tablet may cause weakness or tiredness in some people.

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Liver

Caution

Tepmetko 225 mg Tablet should be used with caution if you have liver disease. Inform your doctor before taking the Tepmetko 225 mg Tablet if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Tepmetko 225 mg Tablet should be used with caution if you have kidney disease. Inform your doctor before taking the Tepmetko 225 mg Tablet if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Safety and effectiveness in patients below the age of 18 years have not been established. Hence, use is not recommended.

Country of origin

India

Manufacturer/Marketer address

L-2, J.R. Complex, Gate No. 4, Village Mandoli, Delhi-110 093, India
Other Info - TEP0031

Author Details

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FAQs

Tepmetko 225 mg Tablet is used to treat Lung cancer (non-small cell lung cancer).
Tepmetko 225 mg Tablet contains Tepotinib, a protein kinase inhibitor that works by blocking the abnormal protein, which can cause uncontrolled cell growth and cancer; thus, it slows or stops cancer growth.
Tepmetko 225 mg Tablet may lead to a change in the heart's electrical activity (QT prolongation). Your doctor conducts ECG tests during treatment to check whether Tepmetko 225 mg Tablet affects your heart rhythm.
It is critical to understand that Tepotinib is not a traditional chemotherapy drug and functions in a different manner. It works by specifically targeting cancer cells and preventing their growth and spread.
While taking Tepmetko 225 mg Tablet , make sure you visit your doctor at all the appointments to ensure that treatment works. Regular monitoring of blood and lipid tests and weight checks are required. An effective way of contraception should be used by both men and women while taking the Tepmetko 225 mg Tablet .
Fertility studies of Tepotinib have not been performed. Discuss the risks of taking this medication with your doctor.

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