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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Stazol 50 Injection is used to treat hereditary angioedema. It contains Stanozolol, a synthetic anabolic-androgenic steroid. It works by decreasing the frequency and severity of the swelling. Anabolic steroids also stimulate growth in the tissues. Stanozolol is also known to reduce bradykinin (inflammatory mediator) production, thus preventing the effect of a bradykinin storm, which is responsible for several complications in COVID-19 patients.
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Prescription drug

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Composition

STANOZOLOL-50MG

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Stazol 50 Injection

Stazol 50 Injection belongs to the class of ‘anabolic steroids' that are primarily used to treat hereditary angioedema, which causes episodes of swelling of the face, extremities, genitals, bowel wall, and throat. It is also used in treating aplastic anaemia (a condition in which the body stops producing enough new blood cells) and as an adjunct therapy in treating vascular disorders and growth failure. 

Stazol 50 Injection contains Stanozolol, a synthetic anabolic-androgenic steroid. It works by decreasing the frequency and severity of the swelling. Anabolic steroids also stimulate growth in the tissues. Stanozolol is also known to reduce bradykinin (inflammatory mediator) production, thus preventing the effect of a bradykinin storm, which is responsible for several complications in COVID-19 patients.

Your doctor will decide the dosage depending on your medical condition. The common side effects of Stazol 50 Injection include menstrual irregularities, acne, difficulty sleeping, changes in sexual desires, and headache. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Before starting Stazol 50 Injection, let your doctor know if you have any history of liver or kidney diseases, prostate cancer, breast cancer, and high blood calcium levels (hypercalcaemia). Stazol 50 Injection is not recommended for pregnant women since it may cause birth defects. Let your doctor know if you are a breastfeeding mother using Stazol 50 Injection. It is not known if Stazol 50 Injection is safe and effective in children; please seek medical advice.

Uses of Stazol 50 Injection

Treatment of Hereditary angioedema

Medicinal Benefits

Stazol 50 Injection treats hereditary angioedema that causes swelling of the face, arms, legs, throat, windpipe, bowels, or sexual organs. It contains Stanozolol, a synthetic anabolic-androgenic steroid that works by decreasing the frequency and severity of the swelling. Stanozolol also reduces bradykinin production, thus preventing the effect of a bradykinin storm, which is responsible for several complications in COVID-19 patients. Stanozolol is also used as an adjunct therapy in vascular disorders and growth failure. 

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Stazol 50 Injection

  • Menstrual irregularities
  • Acne
  • Difficulty sleeping
  • Changes in sexual desires
  • Headache 

Drug Warnings

Inform your doctor if you have any allergic reactions to Stazol 50 Injection or other medications. Before starting Stazol 50 Injection, let your doctor know if you have any medical history of liver/kidney diseases, diabetes, a history of heart attack, high cholesterol levels, and bleeding problems. Stazol 50 Injection is not recommended for use in prostate cancer, breast cancer, and high blood calcium levels (hypercalcaemia). Stazol 50 Injection is not indicated for pregnant women since it may cause birth defects in unborn babies. Let your doctor know if you are a breastfeeding mother using Stazol 50 Injection. It is not known if Stazol 50 Injection is safe and effective in children; please seek medical advice.

Drug Interactions

Drug-Drug Interaction: Stazol 50 Injection may interact with blood thinners (warfarin) and anti-diabetic drugs (glipizide, glimepiride).

Drug-Food Interaction: No interactions were found/established

Drug-Disease Interaction: Stazol 50 Injection is not recommended for use in prostate cancer, breast cancer, and high blood calcium levels (hypercalcaemia).

Drug-Drug Interactions Checker List

  • WARFARIN
  • GLIPIZIDE
  • GLIMEPIRIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.
  • Make a note of your triggers and track your attacks to avoid them.
  • Eat at regular intervals.
  • Keeping your stress under control is important to decrease the frequency of attacks.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

Special Advise

  • Liver functioning tests may be advised by your doctor to monitor your liver health while using Stazol 50 Injection.
  • Your doctor may advise tests for blood sugar levels.

Disease/Condition Glossary

Hereditary angioedema: It is a rare genetic condition that causes severe skin and mucous membrane swelling. The frequency of swelling attacks increases after puberty. The swelling mostly affects: 

a) Skin (face (lips, eyes), hands, arms, legs, genitals, and buttocks); 

b) Gastrointestinal tract (the stomach, intestines, bladder, and urethra)

c) Upper respiratory tract (the larynx and tongue).

Symptoms include swelling, fatigue/tiredness, headache, muscle ache, tingling skin, irritability, mood changes, and painless and non-itchy rash.

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Alcohol

Consult your doctor

It is not known how alcohol consumption affects Stazol 50 Injection. Please consult your doctor for more information.

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Pregnancy

Unsafe

Stazol 50 Injection is not recommended for use in pregnancy. The external genitalia of the female foetus may become virilized if anabolic steroids are used, especially during the first trimester of pregnancy. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving this medicine.

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Breast Feeding

Caution

It is not known whether Stanozolol passes into breast milk. Please consult your doctor before using Stazol 50 Injection if you are a nursing mother.

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Driving

Not applicable

Stazol 50 Injection does not affect your ability to drive.

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Liver

Caution

Inform your doctor if you have or have had liver problems before receiving Stazol 50 Injection. Extreme caution is recommended, and please consult your doctor immediately if you experience abdominal pain, light-coloured stools, dark-coloured urine, unusual fatigue, nausea or vomiting, or yellowing of the skin or eyes while being treated with Stanozolol.

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Kidney

Caution

Inform your doctor if you have or have had kidney problems before receiving Stazol 50 Injection. Your doctor may adjust the dose of this medicine based on your condition.

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Children

Caution

In children under 18, anabolic steroids should be used with caution. Children's growth may be stunted, or their bone growth may be slowed down by this medication. Please consult your doctor for more information.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - ST54805

Author Details

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FAQs

Stazol 50 Injection is used to treat Hereditary angioedema.
Stazol 50 Injection contains Stanozolol, a synthetic anabolic-androgenic steroid that decreases the frequency and severity of the swelling in hereditary angioedema.
Anabolic steroids may interfere with normal bone growth. Hence it is recommended to seek medical advice if you have any bone-related disorders.
Stazol 50 Injection may affect blood sugar levels; therefore, you should consult your doctor if you have diabetes before starting this medicine. You may be advised to take blood or urine sugar tests to check for any changes in your blood sugar levels during the course.

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