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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
REZQ 300MG INJECTION 1ML is used to treat malaria. REZQ 300MG INJECTION 1ML contains Quinine, which treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further. Common side effects of REZQ 300MG INJECTION 1ML are injection site reactions, nausea, restlessness, visual disturbances, vertigo (sudden internal or external spinning sensation), difficulty hearing or ringing in the ears, confusion and nervousness.
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Synonym :

QUININE DIHYDROCHLORIDE

Composition :

QUININE-300MG

Manufacturer/Marketer :

Shreya Life Sciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About REZQ 300MG INJECTION 1ML

REZQ 300MG INJECTION 1ML belongs to the class of anti-malarial drugs primarily used to treat malaria. Malaria is a disease caused by a plasmodium parasite transmitted by the bite of infected Anopheles mosquitoes. When an infected mosquito bites a healthy person, it transmits the 'Plasmodium parasite' into the bloodstream, which affects the red blood cells and liver cells. Malaria symptoms usually start ten days to 4 weeks after the infection. They include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma, and bloody stools. REZQ 300MG INJECTION 1ML is only used to treat malaria but does not prevent it.

REZQ 300MG INJECTION 1ML contains Quinine, which treats malaria. It treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further.

REZQ 300MG INJECTION 1ML will be administered by a qualified healthcare professional; hence do not self-administer. Sometimes, you may experience common side effects like injection site reactions, nausea, restlessness, visual disturbances, vertigo (sudden internal or external spinning sensation), difficulty hearing or ringing in the ears, confusion and nervousness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

REZQ 300MG INJECTION 1ML should be avoided if you are allergic to it. Let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. REZQ 300MG INJECTION 1ML will affect your ability to drive or operate machinery; hence, avoid driving or using machinery. It is recommended not to consume any alcoholic beverages to rule out any possibility of side effects.

Uses of REZQ 300MG INJECTION 1ML

Treatment of Malaria

Directions for Use

REZQ 300MG INJECTION 1ML will be administered by a qualified healthcare professional. Hence, do not self-administer.

Medicinal Benefits

REZQ 300MG INJECTION 1ML belongs to the class of 'anti-malarial drugs,' containing Quinine, primarily used to treat malaria. It treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further.

How REZQ 300MG INJECTION 1ML Works

REZQ 300MG INJECTION 1ML contains Quinine, which treats malaria. It treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further.

Storage

Store in a cool and dry place away from sunlight

Side Effects of REZQ 300MG INJECTION 1ML

  • Injection site reactions
  • Nausea
  • Restlessness
  • Difficulty hearing or ringing in the ears
  • Confusion
  • Nervousness
  • Visual disturbances
  • Vertigo (sudden internal or eternal spinning sensation)

What if I have taken an overdose of REZQ 300MG INJECTION 1ML

As REZQ 300MG INJECTION 1ML is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Before starting treatment with REZQ 300MG INJECTION 1ML, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Inform your doctor if you are pregnant, planning to conceive or a nursing mother. And also, let your doctor know before administrating REZQ 300MG INJECTION 1ML if you have myasthenia gravis (muscle disorders), optic neuritis (Inflammation of the optic nerve), prolonged QT interval or Glucose-6-phosphate Dehydrogenase (G6PD) deficiency. Avoiding alcohol is recommended to rule out any possibility of side effects. REZQ 300MG INJECTION 1ML may cause visual disturbances and vertigo (sudden internal or external spinning sensation); thus, patients should be cautioned not to drive or operate machinery if affected.

Drug-Drug Interactions

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QuinineZiprasidone
Critical
QuinineEfavirenz
Severe

Drug-Drug Interactions

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QuinineZiprasidone
Critical
How does the drug interact with REZQ 300MG INJECTION 1ML:
Co-administration of REZQ 300MG INJECTION 1ML with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking REZQ 300MG INJECTION 1ML with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
QuinineEfavirenz
Severe
How does the drug interact with REZQ 300MG INJECTION 1ML:
Taking Efavirenz and REZQ 300MG INJECTION 1ML can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Efavirenz and REZQ 300MG INJECTION 1ML together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
QuininePazopanib
Severe
How does the drug interact with REZQ 300MG INJECTION 1ML:
Taking Pazopanib with REZQ 300MG INJECTION 1ML may significantly reduces the blood levels of pazopanib.

How to manage the interaction:
Although there is a interaction between Pazopanib and REZQ 300MG INJECTION 1ML, but it can be taken if your doctor has advised it. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, fast or pounding heartbeats, chest pain or tightness, pain in your arms, back, neck, or jaw, shortness of breath, numbness or weakness on one side of your body, and difficulty speaking. Do not stop using any medications without a doctor's advice.
QuinineLoperamide
Severe
How does the drug interact with REZQ 300MG INJECTION 1ML:
When taken in combination REZQ 300MG INJECTION 1ML may significantly raise the loperamide levels in the blood. This can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking loperamide with REZQ 300MG INJECTION 1ML together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
QuinineVigabatrin
Severe
How does the drug interact with REZQ 300MG INJECTION 1ML:
Co-administration of Vigabatrin with REZQ 300MG INJECTION 1ML may increase the risk of serious side effects associated with vision loss, especially if used together for prolonged periods.

How to manage the interaction:
There may be a possibility of interaction between Vigabatrin and REZQ 300MG INJECTION 1ML, but it can be taken if prescribed by a doctor. Routine vision testing is advised during treatment with vigabatrin. Do not discontinue any medications without a doctor's advice.
QuinineAlfuzosin
Severe
How does the drug interact with REZQ 300MG INJECTION 1ML:
Taking Alfuzosin and REZQ 300MG INJECTION 1ML can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Alfuzosin and REZQ 300MG INJECTION 1ML together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
QuinineErythromycin
Severe
How does the drug interact with REZQ 300MG INJECTION 1ML:
Coadministration of REZQ 300MG INJECTION 1ML and erythromycin may significantly increase the blood levels and effects of REZQ 300MG INJECTION 1ML

How to manage the interaction:
Although taking erythromycin and REZQ 300MG INJECTION 1ML together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience headache, flushing, sweating, nausea, vomiting, diarrhoea, stomach pain, dizziness, ringing in the ears, hearing loss, blurred vision, vision loss, and abnormal heart rhythm, contact your doctor immediately. Do not stop using any medications without consulting a doctor.
QuinineGatifloxacin
Severe
How does the drug interact with REZQ 300MG INJECTION 1ML:
Taking Gatifloxacin with REZQ 300MG INJECTION 1ML can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin with REZQ 300MG INJECTION 1ML together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
QuinineLidocaine
Severe
How does the drug interact with REZQ 300MG INJECTION 1ML:
Taking Lidocaine with REZQ 300MG INJECTION 1ML may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Lidocaine and REZQ 300MG INJECTION 1ML together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
QuinineBupivacaine
Severe
How does the drug interact with REZQ 300MG INJECTION 1ML:
Taking Bupivacaine and REZQ 300MG INJECTION 1ML may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking bupivacaine and REZQ 300MG INJECTION 1ML together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat nutritious food containing proteins and vitamins.
  • Consume light and digestible foods such as soups, gruel, khichadi, and rice.
  • Drink plenty of fluids. Lukewarm water is best as it helps in soothing.
  • Consume fruits rich in vitamins A and C, such as lemon, grapes, beetroot, and carrot.
  • Avoid high-fibre foods, fatty foods, junk foods, and caffeine.
  • Spray insecticides at home and outside to prevent mosquito breeding.
  • Cover your skin in areas that are abundant with mosquitoes. Use insect-repellent creams/sprays.
  • Avoid alcohol, coffee, tea, carbonated beverages, and spicy food.

Habit Forming

No

Therapeutic Class

ANTI- MALARIALS

REZQ 300MG INJECTION 1ML Substitute

Substitutes safety advice
  • Cinkona 300 mg Tablet 10's

    5.31per tablet
  • Rez-Q 300 Tablet 10's

    5.31per tablet
  • Rez-Q 300 Injection 2 ml

    10.57per tablet
  • QINARSOL 300MG TABLET

    4.81per tablet
  • Quininga 300 mg Tablet 10's

    4.72per tablet
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Alcohol

Caution

Avoid alcohol while using REZQ 300MG INJECTION 1ML since it can worsen the side effects.

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Pregnancy

Caution

REZQ 300MG INJECTION 1ML is not recommended for use in pregnancy unless clearly necessary. Hence, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing REZQ 300MG INJECTION 1ML.

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Breast Feeding

Caution

REZQ 300MG INJECTION 1ML is not recommended for use while breastfeeding unless clearly necessary. So, inform your doctor if you are a breastfeeding mother. Your doctor will weigh the benefits and potential risks before prescribing REZQ 300MG INJECTION 1ML.

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Driving

Caution

REZQ 300MG INJECTION 1ML may affect your ability to drive or operate machinery. Hence, avoid driving or using machinery until you are alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using the REZQ 300MG INJECTION 1ML. Your doctor may suggest tests for monitoring your liver function while on treatment with REZQ 300MG INJECTION 1ML.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using the REZQ 300MG INJECTION 1ML. Your doctor may suggest tests for monitoring your liver function while on treatment with REZQ 300MG INJECTION 1ML. Dose adjustments may be necessary based on your condition.

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Children

Safe if prescribed

Your doctor will weigh the benefits and potential risks before prescribing REZQ 300MG INJECTION 1ML. The dose of this medicine will be decided by your doctor based on the age and condition of your child.

FAQs

REZQ 300MG INJECTION 1ML is used to treat Malaria.
REZQ 300MG INJECTION 1ML belongs to the class of anti-malarial drugs, containing Quinine that treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further.
You should not take REZQ 300MG INJECTION 1ML if you have or ever had a heart rhythm disorder called Long QT syndrome, glucose-6-phosphate dehydrogenase deficiency (G-6-PD), myasthenia gravis (a muscle disorder), optic neuritis (inflammation of the nerves in your eyes) if taking REZQ 300MG INJECTION 1ML in the past ever caused bleeding.
REZQ 300MG INJECTION 1ML can cause a lowering of blood sugar levels. So, if you are diabetic, please inform your doctor before starting treatment with REZQ 300MG INJECTION 1ML, and dose adjustment might be required depending upon your medical condition.
REZQ 300MG INJECTION 1ML may affect the heart rhythm and cause QT prolongation (heart muscle takes longer than usual to recharge between beats). This QT prolongation can cause a serious fast/irregular heartbeat. Hence it is advised to inform your doctor if you have any heart-related problems like heart failure, slow heartbeat, QT prolongation in EKG or ECG (electrocardiogram) and a family history of heart diseases.
Glucose-6-phosphate dehydrogenase deficiency is a hereditary condition that affects red blood cells. A defect in an enzyme called glucose-6-phosphate dehydrogenase in affected individuals causes red blood cells to break down prematurely. It leads to hemolytic anaemia, which happens when red blood cells are destroyed faster than the body can replenish them.

Country of origin

India

Manufacturer/Marketer address

SHREYA HOUSE, 301/A, Pereira Hill Road, Andheri East, Mumbai - 400 099, India
Other Info - REZ0005

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