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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Qutomal 300mg Injection is used to treat malaria. Qutomal 300mg Injection contains Quinine, which treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further. Common side effects of Qutomal 300mg Injection are injection site reactions, nausea, restlessness, visual disturbances, vertigo (sudden internal or external spinning sensation), difficulty hearing or ringing in the ears, confusion and nervousness.
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Synonym

QUININE DIHYDROCHLORIDE

Composition

QUININE-300MG

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Qutomal 300mg Injection

Qutomal 300mg Injection belongs to the class of anti-malarial drugs primarily used to treat malaria. Malaria is a disease caused by a plasmodium parasite transmitted by the bite of infected Anopheles mosquitoes. When an infected mosquito bites a healthy person, it transmits the 'Plasmodium parasite' into the bloodstream, which affects the red blood cells and liver cells. Malaria symptoms usually start ten days to 4 weeks after the infection. They include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma, and bloody stools. Qutomal 300mg Injection is only used to treat malaria but does not prevent it.

Qutomal 300mg Injection contains Quinine, which treats malaria. It treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further.

Qutomal 300mg Injection will be administered by a qualified healthcare professional; hence do not self-administer. Sometimes, you may experience common side effects like injection site reactions, nausea, restlessness, visual disturbances, vertigo (sudden internal or external spinning sensation), difficulty hearing or ringing in the ears, confusion and nervousness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Qutomal 300mg Injection should be avoided if you are allergic to it. Let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Qutomal 300mg Injection will affect your ability to drive or operate machinery; hence, avoid driving or using machinery. It is recommended not to consume any alcoholic beverages to rule out any possibility of side effects.

Uses of Qutomal 300mg Injection

Treatment of Malaria

Medicinal Benefits

Qutomal 300mg Injection belongs to the class of 'anti-malarial drugs,' containing Quinine, primarily used to treat malaria. It treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further.

Directions for Use

Qutomal 300mg Injection will be administered by a qualified healthcare professional. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Qutomal 300mg Injection

  • Injection site reactions
  • Nausea
  • Restlessness
  • Difficulty hearing or ringing in the ears
  • Confusion
  • Nervousness
  • Visual disturbances
  • Vertigo (sudden internal or eternal spinning sensation)

Drug Warnings

Before starting treatment with Qutomal 300mg Injection, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Inform your doctor if you are pregnant, planning to conceive or a nursing mother. And also, let your doctor know before administrating Qutomal 300mg Injection if you have myasthenia gravis (muscle disorders), optic neuritis (Inflammation of the optic nerve), prolonged QT interval or Glucose-6-phosphate Dehydrogenase (G6PD) deficiency. Avoiding alcohol is recommended to rule out any possibility of side effects. Qutomal 300mg Injection may cause visual disturbances and vertigo (sudden internal or external spinning sensation); thus, patients should be cautioned not to drive or operate machinery if affected.

Drug Interactions

Drug-Drug Interactions: Qutomal 300mg Injection may interact with azole antifungal drugs (e.g. fluconazole), antiretroviral drugs used to treat HIV (e.g. ritonavir), CYP3A4 inducers (e.g. rifampicin), medicines used to control seizures (e.g. phenobarbital, carbamazepine, phenytoin) and other CYP3A4 substrates.

Drug-Food Interactions: Qutomal 300mg Injection is known to interact with St John's Wort plant (a natural remedy to treat depression) and alcohol.

Drug-Disease Interactions: Qutomal 300mg Injection may interact with disease conditions including hypokalemia, arrhythmias, magnesium imbalance, G-6-PD deficiency (glucose-6-phosphate dehydrogenase deficiency), myasthenia gravis (a muscle weakness problem), ocular toxicity (visual disturbances), thrombocytopenia (deficiency of platelets), tinnitus (Ringing or buzzing noise in one or both ears) and liver or kidney impairment.

Drug-Drug Interactions Checker List

  • FLUCONAZOLE
  • RITONAVIR
  • RIFAMPICIN
  • PHENOBARBITAL
  • CARBAMAZEPINE
  • PHENYTOIN

Habit Forming

No

Diet & Lifestyle Advise

  • Eat nutritious food containing proteins and vitamins.
  • Consume light and digestible foods such as soups, gruel, khichadi, and rice.
  • Drink plenty of fluids. Lukewarm water is best as it helps in soothing.
  • Consume fruits rich in vitamins A and C, such as lemon, grapes, beetroot, and carrot.
  • Avoid high-fibre foods, fatty foods, junk foods, and caffeine.
  • Spray insecticides at home and outside to prevent mosquito breeding.
  • Cover your skin in areas that are abundant with mosquitoes. Use insect-repellent creams/sprays.
  • Avoid alcohol, coffee, tea, carbonated beverages, and spicy food.

Special Advise

 

Disease/Condition Glossary

Malaria: Malaria is a life-threatening disease caused by parasites entering the body through mosquito bites. This is a common disease in countries like Africa, South America and Southern Asia. This disease usually occurs when an Anopheles mosquito (infected with the parasite 'Plasmodium') bites a healthy individual and transfers the parasite into the bloodstream. Parasites that cause malaria include Plasmodium vivax, P. ovale, P. malaria and P. falciparum. Malaria symptoms usually start ten days to 4 weeks after the infection. They include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma and bloody stools.

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Alcohol

Caution

Avoid alcohol while using Qutomal 300mg Injection since it can worsen the side effects.

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Pregnancy

Caution

Qutomal 300mg Injection is not recommended for use in pregnancy unless clearly necessary. Hence, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Qutomal 300mg Injection.

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Breast Feeding

Caution

Qutomal 300mg Injection is not recommended for use while breastfeeding unless clearly necessary. So, inform your doctor if you are a breastfeeding mother. Your doctor will weigh the benefits and potential risks before prescribing Qutomal 300mg Injection.

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Driving

Caution

Qutomal 300mg Injection may affect your ability to drive or operate machinery. Hence, avoid driving or using machinery until you are alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using the Qutomal 300mg Injection. Your doctor may suggest tests for monitoring your liver function while on treatment with Qutomal 300mg Injection.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using the Qutomal 300mg Injection. Your doctor may suggest tests for monitoring your liver function while on treatment with Qutomal 300mg Injection. Dose adjustments may be necessary based on your condition.

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Children

Safe if prescribed

Your doctor will weigh the benefits and potential risks before prescribing Qutomal 300mg Injection. The dose of this medicine will be decided by your doctor based on the age and condition of your child.

Country of origin

India
Other Info - QU64610

Author Details

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FAQs

Qutomal 300mg Injection is used to treat Malaria.
Qutomal 300mg Injection belongs to the class of anti-malarial drugs, containing Quinine that treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further.
You should not take Qutomal 300mg Injection if you have or ever had a heart rhythm disorder called Long QT syndrome, glucose-6-phosphate dehydrogenase deficiency (G-6-PD), myasthenia gravis (a muscle disorder), optic neuritis (inflammation of the nerves in your eyes) if taking Qutomal 300mg Injection in the past ever caused bleeding.
Qutomal 300mg Injection can cause a lowering of blood sugar levels. So, if you are diabetic, please inform your doctor before starting treatment with Qutomal 300mg Injection, and dose adjustment might be required depending upon your medical condition.
Qutomal 300mg Injection may affect the heart rhythm and cause QT prolongation (heart muscle takes longer than usual to recharge between beats). This QT prolongation can cause a serious fast/irregular heartbeat. Hence it is advised to inform your doctor if you have any heart-related problems like heart failure, slow heartbeat, QT prolongation in EKG or ECG (electrocardiogram) and a family history of heart diseases.
Glucose-6-phosphate dehydrogenase deficiency is a hereditary condition that affects red blood cells. A defect in an enzyme called glucose-6-phosphate dehydrogenase in affected individuals causes red blood cells to break down prematurely. It leads to hemolytic anaemia, which happens when red blood cells are destroyed faster than the body can replenish them.

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