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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:40 PM IST
Ramnocv 500 ER Tablet is used alone or with other medicines to treat angina pectoris. It helps prevent any further attack of angina by making the heart work more efficiently, and it is used as an add-on to existing treatment in patients whose disease is not adequately controlled by other medicines for angina pectoris, such as beta-blockers or calcium antagonists, or in patients who cannot take these medicines. In some cases, it may cause side effects such as constipation, dizziness, headache, or feeling sick. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Composition

RANOLAZINE-500MG

Manufacturer/Marketer

Athena Pharmaceuticals

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Ramnocv 500 ER Tablet

Ramnocv 500 ER Tablet is used alone or with other medicines to treat angina pectoris. Angina pectoris is discomfort in the chest or chest pain, which generally occurs due to coronary artery disease (CAD) when an adequate amount of oxygen and blood is not reaching the heart and its muscles. It can also be due to the blockage of the heart's arteries. It helps prevent any further attack of angina by making the heart work more efficiently, and it is used as an add-on to existing treatment in patients whose disease is not adequately controlled by other medicines for angina pectoris, such as beta-blockers or calcium antagonists, or in patients who cannot take these medicines.

The active substance in Ramnocv 500 ER Tablet is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels, through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Ramnocv 500 ER Tablet is thought to help the heart relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Your doctor will tell you how to take the Ramnocv 500 ER Tablet based on your medical condition. You may sometimes experience constipation, dizziness, headache, or feeling sick. Most of these side effects of Ramnocv 500 ER Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not consume Ramnocv 500 ER Tablet if you are allergic to any component in this medicine. Ramnocv 500 ER Tablet should not be stopped even if you feel better for the best results, as it prevents any future harm. If you stop taking the Ramnocv 500 ER Tablet on your own, your chest pain can come back in more severe form. If you plan to get pregnant or are pregnant or breastfeeding, please consult your doctor to avoid any unwanted harm to the baby. Some lifestyle modifications are important for best results when taking Ramnocv 500 ER Tablet , like smoking cessation, decreasing alcohol intake, eating well, regular exercise, and managing stress. Ramnocv 500 ER Tablet should be taken with caution if you have any liver or kidney problems. Also, inform your doctor if you are taking other medications to avoid unwanted side effects or contraindications.

Uses of Ramnocv 500 ER Tablet

Treatment of Angina Pectoris.

Medicinal Benefits

Ramnocv 500 ER Tablet is prescribed for treating angina. Ramnocv 500 ER Tablet is an anti-anginal medication used to treat angina pectoris. It reduces sodium ions' flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called ‘sodium-dependent calcium channels’ through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Ramnocv 500 ER Tablet is thought to help the heart relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Directions for Use

Swallow Ramnocv 500 ER Tablet as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ramnocv 500 ER Tablet

  • Constipation
  • Dizziness
  • Headache
  • Feeling sick

Drug Warnings

Ramnocv 500 ER Tablet should be taken with caution in liver/kidney disease, are pregnant, plan to become pregnant, or are breastfeeding, history of heart disease. Also, grapefruit juice should be avoided while taking Ramnocv 500 ER Tablet . As a precautionary measure, junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery. Do regular exercise to avoid the feeling of heaviness in the abdomen.

Drug Interactions

 Drug-Drug Interactions: Ramnocv 500 ER Tablet is known to contra-indicate in certain medicines to treat bacterial infections (clarithromycin, telithromycin), lipid-lowering drugs (simvastatin, atorvastatin), fungal infections (itraconazole, ketoconazole, voriconazole, posaconazole), HIV infection (protease inhibitors), depression (nefazodone), antipsychotic medications (haloperidol), or heart rhythm disorders (quinidine, dofetilide, or sotalol).

Drug-Food Interactions: Ramnocv 500 ER Tablet may interact with other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Also, grapefruit juice should be avoided while taking Ramnocv 500 ER Tablet .

Drug-Disease Interactions: Caution should be exercised if used in patients with severe hepatic impairment, renal disease, long QT interval, or using other QT- prolonging drugs.

Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • QUINIDINE
  • DOFETILIDE
  • SOTALOL
  • KETOCONAZOLE
  • ITRACONAZOLE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a healthy lifestyle by exercising regularly, maintaining weight, and eating a healthy diet.

  • If you suffer from kidney or liver disease, please inform your doctor before taking the Ramnocv 500 ER Tablet .
  • Alcohol consumption along with Ramnocv 500 ER Tablet should be avoided as it may cause excessive drowsiness and increase muscle pain.
  • As a precautionary measure, junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery.

Disease/Condition Glossary

Angina pectoris: Angina pectoris is discomfort in the chest or chest pain that generally occurs due to coronary artery disease (CAD) when an adequate amount of oxygen and blood is not reaching the heart and its muscles. It can also be due to the blockage of the heart's arteries. It helps prevent any further attack of angina by making the heart work more efficiently, but it does not stop an acute attack of angina pectoris.

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Alcohol

Safe if prescribed

Ramnocv 500 ER Tablet does not have any reported interaction; hence, if you experience any difficulty, discuss with your doctor.

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Pregnancy

Unsafe

Ramnocv 500 ER Tablet should not be used when pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Ramnocv 500 ER Tablet .

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Breast Feeding

Unsafe

Ramnocv 500 ER Tablet should not be used in nursing mothers. Please consult the doctor if you have any concerns regarding this.

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Driving

Safe if prescribed

Ramnocv 500 ER Tablet does not have any reported interaction; hence, in case you experience any difficulty, discuss with your doctor.

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Liver

Caution

Ramnocv 500 ER Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Ramnocv 500 ER Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Ramnocv 500 ER Tablet is not recommended for children below the age of 18. The safety and effectiveness of Ramnocv 500 ER Tablet have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

Country of origin

India
Other Info - RAM0279

Author Details

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FAQs

Ramnocv 500 ER Tablet is used alone or with other medicines to treat angina pectoris.
The active substance in Ramnocv 500 ER Tablet is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Ramnocv 500 ER Tablet is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.
No, Ramnocv 500 ER Tablet does not stop acute attacks (sudden attacks) of angina, but Ramnocv 500 ER Tablet helps prevent a new attack.
No, alcohol should not be taken with Ramnocv 500 ER Tablet as it may lead to unwanted side effects and increase angina attacks.
Yes, smoking (tobacco) decreases the efficacy of Ramnocv 500 ER Tablet , especially when taken for angina (chest pain), so it should be avoided while taking Ramnocv 500 ER Tablet .
Yes, Ramnocv 500 ER Tablet can cause an upset stomach when taken empty stomach. So, to avoid it, Ramnocv 500 ER Tablet should be taken with a meal for best results.
Yes, Ramnocv 500 ER Tablet can cause drowsiness. If you feel excessively sleepy, please consult your doctor for better advice.
Some major side effects include a rapid, pounding, or irregular heartbeat, difficulty breathing, and fainting. If you encounter any of these symptoms, contact your doctor immediately.
Do not take more than the prescribed dose of Ramnocv 500 ER Tablet as it may cause overdose. The symptoms of overdose include nausea, vomiting, confusion, dizziness, double vision, fainting, difficulty speaking, uncontrollable shaking of a part of the body, hallucinations and burning, pain, numbness, or tingling in any part of the body. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
Ramnocv 500 ER Tablet may increase the blood levels and effects of metoprolol. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects.
Ramnocv 500 ER Tablet might raise metformin levels, increasing the risk of lactic acidosis. If you are prescribed ranolazine while taking metformin, discuss it with a healthcare physician. They may offer a lesser dose of metformin as a safer alternative.
You can take it if prescribed by the doctor. However, limit simvastatin to 20 mg once daily in individuals taking any dose of Ramnocv 500 ER Tablet .

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