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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Mebifast 5/135 Tablet is used to treat painful stomach cramps in the condition of irritable bowel syndrome (IBS) with bloating. It contains Mebeverine and Chlordiazepoxide, which works by relaxing the intestinal muscle wall, thereby providing relief from painful muscle spasms. Also, it decreases the abnormal activity of nerve cells. Thus, it relaxes intestinal muscles, reduces stomach pain caused by spasms, cramps, gas formation, and bloating, and minimizes anxiety levels caused due to stomach discomfort. In some cases, it may cause side effects such as drowsiness, dizziness, light-headedness, slurred speech, tiredness, lack of coordination, or difficulty in controlling movements. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Winmark Healthcare Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Mebifast 5/135 Tablet

Mebifast 5/135 Tablet belongs to a class of drugs called 'antispasmodics' primarily used to treat painful stomach cramps in the condition of irritable bowel syndrome (IBS) with bloating. Irritable bowel syndrome is a common disease that affects the large intestine. IBS is also known as spastic colon, irritable colon, spastic colitis, and mucous colitis. An irritable bowel syndrome is a group of intestinal symptoms that occur together.

Mebifast 5/135 Tablet is a combination of two drugs: Mebeverine (antispasmodic) and Chlordiazepoxide (benzodiazepine). Mebeverine works by relaxing the intestinal muscle wall, thereby providing relief from painful muscle spasms. On the other hand, Chlordiazepoxide works by increasing a chemical messenger known as GABA (nerve-calming agent) activity in the brain, thereby decreasing nerve cells' abnormal activity. Thus, together it relaxes intestinal muscles, reduces stomach pain caused by spasms, cramps, gas formation, and bloating, and minimizes anxiety levels caused due to stomach discomfort. 

Take Mebifast 5/135 Tablet as prescribed. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience drowsiness, dizziness, light-headedness, slurred speech, tiredness, lack of coordination, or difficulty in controlling movements. Most of these side effects of Mebifast 5/135 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Mebifast 5/135 Tablet or any other medicines, please tell your doctor. Mebifast 5/135 Tablet is not recommended for children below 18 years of age, as the safety and effectiveness were not established. You are advised not to take Mebifast 5/135 Tablet if you are pregnant or planning for pregnancy as it may cause congenital disabilities (congenital disabilities). Mebifast 5/135 Tablet may be excreted in breast milk. Therefore, avoid taking Mebifast 5/135 Tablet if you are breastfeeding. Mebifast 5/135 Tablet should be used with caution in the elderly as it may confuse them. Do not take Mebifast 5/135 Tablet for longer than the prescribed period as it may cause dependence. Please do not stop taking Mebifast 5/135 Tablet on your own as it might cause withdrawal symptoms. If you have vaginal bleeding or discharge, difficulty in urination, fever, constipation, blood in stools, myasthenia gravis (muscle weakness), anxiety disorders, depression, schizophrenia, manic depression, sleep apnoea (breathing stops and repeatedly starts during sleep), kidney or liver problems, inform your doctor before taking Mebifast 5/135 Tablet .

Uses of Mebifast 5/135 Tablet

Treatment of Irritable bowel syndrome (IBS), Painful stomach cramps.

Medicinal Benefits

Mebifast 5/135 Tablet is a combination of two drugs: Mebeverine and Chlordiazepoxide to treat symptoms of irritable bowel syndrome (IBS) and painful stomach cramps. Mebeverine belongs to the class of antispasmodics that works by relieving contractions associated with smooth muscles of the stomach and intestine. Chlordiazepoxide is a benzodiazepine that increases GABA (nerve-calming agent) activity in the brain and decreases nerve cells' abnormal active cells. Thereby relaxing muscles and reducing anxiety caused due to painful stomach cramps. 

Directions for Use

Take Mebifast 5/135 Tablet on an empty stomach preferably 20 minutes before a meal or as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mebifast 5/135 Tablet

  • Drowsiness
  • Dizziness
  • Light-headedness
  • Slurred speech
  • Tiredness
  • Lack of coordination
  • Difficulty in controlling movements

Drug Warnings

If you are known to be allergic to Mebifast 5/135 Tablet or any other medicines, please tell your doctor. Mebifast 5/135 Tablet is not recommended for children below 18 years of age, as the safety and effectiveness were not established. Avoid taking Mebifast 5/135 Tablet if you are pregnant or planning for pregnancy as it may cause congenital disabilities (congenital disabilities). Mebifast 5/135 Tablet may be excreted in breast milk. Therefore, avoid taking Mebifast 5/135 Tablet if you are breastfeeding. Mebifast 5/135 Tablet should be used with caution in the elderly as it may cause confusion in them. Do not take Mebifast 5/135 Tablet for longer than the prescribed period as it may cause dependence. Please do not stop taking Mebifast 5/135 Tablet on your own as it might cause withdrawal symptoms. If you cannot digest or tolerate any sugars, please tell your doctor as Mebifast 5/135 Tablet contains sucrose and lactose. If you have vaginal bleeding or discharge, difficulty in urination, fever, constipation, blood in stools, myasthenia gravis (muscle weakness), anxiety disorders, depression, schizophrenia, manic depression, sleep apnoea (breathing stops and repeatedly starts during sleep), spinal or cerebral ataxia, kidney or liver problems, inform your doctor before taking Mebifast 5/135 Tablet .

Drug Interactions

Drug-Drug Interaction: Mebifast 5/135 Tablet may interact with pain killers (codeine, morphine), blood thinner (warfarin), benzodiazepine (diazepam), anticonvulsants (phenobarbitone, phenytoin), antibiotics (rifampicin), muscle relaxant (baclofen), antiparkinson drug (levodopa), antacids (cimetidine, omeprazole), heart-related medicines (digoxin), water pills (furosemide), bronchodilator (theophylline), anti-allergic drug (chlorphenamine).

Drug- Food Interaction: Avoid the intake of alcohol with Mebifast 5/135 Tablet as it may increase drowsiness.

Drug-Disease Interaction: If you have vaginal bleeding or discharge, difficulty in urination, fever, constipation, blood in stools, myasthenia gravis (muscle weakness), anxiety disorders, depression, schizophrenia, manic depression, sleep apnoea (breathing stops and starts repeatedly during sleep), spinal or cerebral ataxia, kidney or liver problems, inform your doctor before taking Mebifast 5/135 Tablet .

Drug-Drug Interactions Checker List

  • CODEINE
  • MORPHINE
  • WARFARIN
  • DIAZEPAM
  • PHENOBARBITONE
  • PHENYTOIN
  • RIFAMPICIN
  • BACLOFEN
  • LEVODOPA
  • CIMETIDINE
  • OMEPRAZOLE
  • DIGOXIN
  • FUROSEMIDE
  • THEOPHYLLINE
  • CHLORPHENIRAMINE

Habit Forming

Yes

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight by exercising regularly.
  • Avoid carbonated and caffeinated beverages.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
  • Avoid deep-fried and spicy foods.
  • Foods containing probiotics may help in providing relief from gas and bloating.

Special Advise

Please consult a doctor if the symptoms persist or worsen after using Mebifast 5/135 Tablet for more than 2 weeks.

Disease/Condition Glossary

Irritable bowel syndrome (IBS): It is a common disease that affects the large intestine. IBS is also known as irritable colon, spastic colon, spastic colitis, and mucous colitis. An irritable bowel syndrome is a group of intestinal symptoms that occur together. The exact cause is unknown, but common causes of IBS are acidity, stress, carbonated foods, and beverages, irregular hormone levels, certain food, and medications. Symptoms include abdominal pain, cramps, bloating, gas, constipation, and/or diarrhoea.

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Alcohol

Unsafe

Avoid alcohol consumption with Mebifast 5/135 Tablet as it may increase drowsiness. Please consult a doctor before consuming alcohol while using Mebifast 5/135 Tablet .

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Pregnancy

Unsafe

Mebifast 5/135 Tablet is not recommended for pregnant women as it may cause harm the foetus. However, please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Mebifast 5/135 Tablet is not recommended for breastfeeding mothers as it is excreted in breast milk.

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Driving

Caution

Mebifast 5/135 Tablet may cause drowsiness, dizziness or blurred vision in some people. So, drive only if you are alert and your vision is clear after taking Mebifast 5/135 Tablet .

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Liver

Caution

Take Mebifast 5/135 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Mebifast 5/135 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Mebifast 5/135 Tablet is not recommended for children below 18 years as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

A-36, Sector 60, Noida, Uttar Pradesh, India., Pin-201 304.
Other Info - MEB0086

Author Details

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FAQs

Mebifast 5/135 Tablet is used to treat painful stomach cramps in the condition of irritable bowel syndrome (IBS) with bloating.
Mebifast 5/135 Tablet contains Mebeverine and Chlordiazepoxide. Mebeverine belongs to the class of antispasmodics that relaxes the muscles in the walls of the intestine and provides relief from painful muscle spasms. Thus, it reduces stomach pain caused by spasm, cramps, and gas formation, bloating, and discomfort. Chlordiazepoxide works by increasing GABA (nerve-calming agent) activity in the brain and decreasing the abnormal activity of nerve cells. Thereby, relaxes muscles, increases its calming action and reduces anxiety.
Mebifast 5/135 Tablet may cause dependence in patients especially when taken at high doses, for longer durations, or in patients with a history of drug abuse or alcoholism. Therefore, take Mebifast 5/135 Tablet only as prescribed.
Dizziness may be a side effect of Mebifast 5/135 Tablet . However, you are recommended to avoid driving if you feel dizzy after taking Mebifast 5/135 Tablet .
Yes, Mebifast 5/135 Tablet reduces stomach pain which is a symptom of irritable bowel syndrome. Mebifast 5/135 Tablet contains Mebeverine, an antispasmodic agent which reduces spasms, cramps and stomach pain. However, please consult a doctor before taking Mebifast 5/135 Tablet .
You are not recommended to take Mebifast 5/135 Tablet with diazepam as co-administration of these two medicines may increase the risk of adverse effects such as drowsiness, dizziness, difficulty in concentrating, or confusion. However, please consult your doctor before taking Mebifast 5/135 Tablet with other medicines.
Mebifast 5/135 Tablet should be used with caution in elderly patients. Mebifast 5/135 Tablet contains Chlordiazepoxide which may cause confusion in the elderly. However, please consult a doctor so that the dose may be adjusted appropriately.

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