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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:20 PM IST
Granichem 1mg Injection is used to treat nausea and vomiting caused by medical treatments after surgery, chemotherapy, or radiation treatment for cancer. It contains Granisetron, which works by blocking the brain's serotonin (chemical messenger) activity that triggers nausea and vomiting during cancer treatment (chemotherapy or radiation therapy) or after surgery. Common side effects of Granichem 1mg Injection include diarrhoea, constipation, stomach pain, weakness, headache, fever, drowsiness, trouble sleeping, pain, redness, and swelling at the injection site.
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Composition :

GRANISETRON-1MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Granichem 1mg Injection

Granichem 1mg Injection belongs to the class of 'anti-emetic' drugs, primarily used to treat nausea and vomiting caused by medical treatments after surgery or chemotherapy or radiation treatment for cancer. Nausea is defined as stomach discomfort and the sensation of an urge to vomit. Vomiting is the forcible voluntary or involuntary emptying of contents of the stomach through the mouth.

Granichem 1mg Injection contains an anti-emetic (eases vomiting symptoms) medicine, 'Granisetron', that belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). It works by blocking the brain's serotonin (chemical messenger) activity that triggers nausea and vomiting during cancer treatment (chemotherapy or radiation therapy) or after surgery.

Granichem 1mg Injection will be administered by a healthcare professional; do not self-administer. Your doctor will decide the dose and duration based on the severity of your medical condition. Common side effects of Granichem 1mg Injection include diarrhoea, constipation, stomach pain, weakness, headache, fever, drowsiness, trouble sleeping, pain, redness, and swelling at the injection site. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

If you use other prescription or non-prescription medicines, inform your doctor before using Granichem 1mg Injection. Let your doctor know if you have any liver, kidney or heart diseases, stomach/intestinal problems, allergic reactions, and low levels of potassium and magnesium in the blood before starting Granichem 1mg Injection. This medicine may make you dizzy or drowsy; hence avoid driving or operating machinery if you are not mentally alert. Consult your doctor before using Granichem 1mg Injection if you are pregnant, planning for pregnancy or breastfeeding. Avoid consuming alcohol while being treated with Granichem 1mg Injection as it could lead to unwanted side effects. 

Uses of Granichem 1mg Injection

Treatment of Nausea and vomiting

Medicinal Benefits

Granichem 1mg Injection contains an anti-emetic medicine, 'Granisetron', that treats nausea and vomiting caused due to cancer treatment (chemotherapy or radiation therapy) or after surgery. Granisetron belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). When the cells lining the gastrointestinal tract are damaged by chemotherapy or radiation therapy, they release a natural substance called serotonin (5HT3, 5-hydroxytryptamine). This serotonin binds to serotonin receptors on nerves that induces nausea and vomiting. Granichem 1mg Injection works by blocking the brain's serotonin activity and preventing postoperative nausea and vomiting. 

Side Effects of Granichem 1mg Injection

  • Diarrhoea
  • Constipation
  • Stomach pain
  • Weakness
  • Headache
  • Fever
  • Dizziness
  • Drowsiness
  • Trouble sleeping
  • Pain, redness, and swelling at the injection site

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Seeking medical advice if you use prescription or non-prescription medicines while being treated with Granichem 1mg Injection is suggested. Inform your doctor about a history of stomach/intestinal problems, heart diseases, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases before starting Granichem 1mg Injection. Please consult your doctor if you are pregnant or breastfeeding if the doctor advised you Granichem 1mg Injection. This medicine may make you feel dizzy, so drive or operate machinery only if you are alert. Avoid consuming alcohol during the course, as it could lead to increased dizziness. Granichem 1mg Injection is not recommended in children below two years of age.

Therapeutic Class

ANTIEMETICS

Diet & Lifestyle Advise

  • Avoid chocolates, junk food, cheese, processed food, alcohol, and smoking. 
  • You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy, and stress reduction techniques.
  • Drink enough water to stay hydrated and limit or avoid alcohol and caffeine.
  • Include a diet rich in whole grains, vegetables, and fruits.
  • You can include antioxidants in your daily diet, like ashwagandha, omega-3 fatty acids, green tea, and lemon.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Habit Forming

No

What if I have taken an overdose of Granichem 1mg Injection

Since Granichem 1mg Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Granichem 1mg Injection may cause headache.
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Alcohol

Caution

You are recommended to limit or avoid alcohol consumption while taking Granichem 1mg Injection. Alcohol intake, along with Granichem 1mg Injection, may lead to unwanted side effects and cause increased dizziness.

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Pregnancy

Caution

It is not known if Granichem 1mg Injection affects pregnancy. Please inform your doctor if you are pregnant or planning pregnancy before receiving Granichem 1mg Injection.

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Breast Feeding

Caution

It is not known if this medicine passes into breast milk. Please inform your doctor before taking Granichem 1mg Injection if you are a nursing mother.

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Driving

Caution

Granichem 1mg Injection may make you feel dizzy, affecting your mental ability. Do not drive or operate machinery if you experience dizziness.

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Liver

Caution

Granichem 1mg Injection should be used with caution if you have liver disease. Please inform your doctor if you have a history of liver impairment before starting Granichem 1mg Injection.

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Kidney

Caution

Granichem 1mg Injection should be used with caution if you have kidney problems. Please inform your doctor if you have a history of kidney impairment/kidney disease.

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Children

Caution

Safety and efficacy of Granichem 1mg Injection have not been established in children below 2 years of age.

Country of origin

India
Other Info - GR35933

Author Details

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FAQs

Granichem 1mg Injection is used to treat Nausea and vomiting.
Granichem 1mg Injection contains Granisetron, an anti-emetic drug. It is a serotonin blocker that blocks the activity of serotonin, a chemical messenger that induces nausea and vomiting after treatments like chemotherapy and radiation therapy. Thus, Granichem 1mg Injection relieves post-operative nausea and vomiting symptoms.
Granichem 1mg Injection may cause constipation as one of its side effects. You can avoid it by including high-fibre food in your diet that improves your digestion. Limit the intake of alcohol to manage your constipation.
Granichem 1mg Injection should be used with caution if you have recent stomach/intestinal problems like stomach ache, wind, feeling or being sick, difficulty passing stools, heart rhythm disorder, a recent stomach or intestinal surgery, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases.
You are advised to complete the course prescribed by your doctor. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of nausea and vomiting.
Common side effects of Granichem 1mg Injection include diarrhoea, constipation, stomach pain, weakness, headache, fever, drowsiness, trouble sleeping, pain, redness, and swelling at the injection site. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.
It is not known if Granichem 1mg Injection affects pregnancy. Please inform your doctor if you are pregnant or planning pregnancy before receiving Granichem 1mg Injection. The doctor will prescribe Granichem 1mg Injection only if clearly needed.
Few studies suggest that Granichem 1mg Injection is more effective than ondansetron. However, the doctor will decide which medicine is suitable and better for you based on your condition.

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