Treosulfan
About Treosulfan
Treosulfan belongs to the group of anti-cancer medicines called alkylating agents indicated in the treatment of advanced ovarian cancer after at least one prior standard therapy. Ovarian cancer occurs when abnormal cells grow and multiply in the ovaries and fallopian tubes.
Treosulfan contains Treosulfan, which works by inhibiting tumour growth. It prevents the cancer cells from multiplying. This helps reduce the number of cancer cells and helps treat ovarian cancer.
In some cases, Treosulfan may cause side effects such as nausea, vomiting, mild hair loss, and bronze discolouration of the skin. Most of these side effects may not require medical attention and resolve over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
Consult the doctor if you are pregnant, breastfeeding, or think you may be pregnant or are planning for pregnancy. Treosulfan is not recommended for children. Inform the doctor about your health condition and medications to rule out any side effects/interactions.
Uses of Treosulfan
Medicinal Benefits
Treosulfan belongs to the group of anti-cancer medicines called bifunctional alkylating agents indicated in the treatment of advanced ovarian cancer after at least one prior standard therapy. Treosulfan contains Treosulfan, which works by inhibiting tumour growth. Thereby, it helps treat ovarian cancer.
Directions for Use
Storage
Side Effects of Treosulfan
- Nausea
- Vomiting
- Mild hair loss
- Bronze discolouration of the skin
Drug Warnings
Do not use Treosulfan if you are allergic to any of its components, if you have severe bone marrow depression, or if you are breastfeeding. Inform the doctor if you have lung inflammation, kidney problems or if you are undergoing any vaccination. Be cautious as Treosulfan may increase the risk of infections and blood cancers after long-term treatment. Consult the doctor if you are pregnant, think you are pregnant or planning for pregnancy. Let the doctor know if you are taking any other medicines, including supplements and herbal products.
Drug Interactions
Drug-Drug Interactions: Inform the doctor if you are taking painkillers (ibuprofen) or anti-malarial (chloroquine).
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Inform the doctor if you have severe bone marrow depression or kidney problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorIt is not known if alcohol affects Treosulfan. Please consult your doctor.
Pregnancy
cautionTreosulfan should not be used during pregnancy unless prescribed by the doctor. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Treosulfan.
Breast Feeding
unsafeAvoid breastfeeding whilst on treatment with Treosulfan.
Driving
cautionTreosulfan may cause nausea or vomiting. Drive or operate heavy machinery only if you are alert.
Liver
consult your doctorIf you have a history of liver disease, inform your doctor before receiving Treosulfan.
Kidney
cautionIf you have a history of kidney diseases, inform your doctor before receiving Treosulfan. Dose adjustment may be needed in patients with impaired kidney function.
Children
unsafeTreosulfan is not recommended for children due to a lack of data on the safety and effectiveness.
Habit Forming
Diet & Lifestyle Advise
- Eat a healthy diet and exercise regularly to maintain proper weight.
- Avoid smoking and alcohol consumption.
- Include vegetables, fruits, and whole grains in your diet.
- Avoid fast food, fried food, processed meats, refined carbs and added sugar.
- Get optimal sleep; rest well.
- Drink plenty of water or other fluids.
Special Advise
- Your doctor may advise regular blood tests to check for blood cell count.
- Women of childbearing potential must use reliable contraception during treatment with Treosulfan and for at least six months after the treatment.
- Drink more fluids than usual for up to 24 hours after your treatment.
Patients Concern
Disease/Condition Glossary
Ovarian Cancer: Ovarian cancer occurs when abnormal cells grow and multiply in the ovaries and fallopian tubes. Signs and symptoms include pain, swelling, or a feeling of pressure in the pelvis or abdomen, frequent or sudden urge to urinate, feeling full or trouble eating, a lump in the pelvic area, gas, bloating, or constipation.
FAQs
Treosulfan is used to treat Ovarian cancer.
Treosulfan works by inhibiting tumour growth. Thereby, it helps treat ovarian cancer.
Treosulfan may cause mild hair loss. The hair may grow back after the treatment with Treosulfan. However, consult your doctor if you have any concerns.
The risk of generalised infection may be increased after some vaccinations. Therefore, do not receive any live vaccinations during therapy.
There are no specific foods or drinks you need to avoid while taking Treosulfan. However, it is important to follow your doctor’s instructions regarding any dietary or lifestyle considerations. Consult the doctor if you have any concerns.
Bleeding gums after brushing your teeth while taking Treosulfan might be a side effect. It may affect your immune system and blood clotting, making your gums more susceptible to bleeding. It is important to maintain proper oral hygiene but avoid brushing too hard. Consult the doctor, if the bleeding persists or worsens.
To cope with tiredness and weakness after starting treatment with Treosulfan, ensure you get plenty of rest, eat a nutritious diet rich in iron, protein, and complex carbohydrates, stay hydrated by drinking water, and consider light physical activity like walking to boost energy. Consult the doctor, if tiredness and weakness persist or worsen.
If you have noticed changes in your skin after taking Treosulfan, it is important to consult the doctor. Skin changes might be a side effect of this medication, and the doctor can help determine the cause and may recommend adjusting your treatment or providing advice on how to manage the skin changes. Meanwhile, avoid using harsh skincare products and protect your skin from prolonged sun exposure.
Avoid smoking, consumption of alcohol, fried food, fast food, processed meats, refined carbs and added sugar during treatment with Treosulfan. Additionally, avoid breastfeeding while treatment with Treosulfan as it may pass into breastmilk.
Treosulfan can be received during pregnancy only if it is administered by the doctor or nurse. The doctor will prescribe this medication only if the potential benefits outweigh the risks.
The doctor may recommend several tests before and during treatment with Treosulfan including blood tests to monitor liver and kidney function, blood cell counts, and signs of infection. Additionally, your doctor may perform regular heart function assessments and monitor your overall response to the treatment. However, specific tests may depend on your health condition and the doctor's recommendations.
The side effects of Treosulfan include mild hair loss, nausea, vomiting, and bronze discolouration of the skin. Consult the doctor if any of these side effects persist or worsen.
