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TIZANIDINE+ACECLOFENAC

About TIZANIDINE+ACECLOFENAC

TIZANIDINE+ACECLOFENAC is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, and headache. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.
 
TIZANIDINE+ACECLOFENAC contains Tizanidine (muscle relaxant) and Aceclofenac (NSAID). Tizanidine works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac works by blocking the effect of prostaglandins, which cause pain and inflammation. Thus, it reduces mild to moderate pain and inflammation. Together, TIZANIDINE+ACECLOFENAC helps in relieving pain due to muscle spasms.
 
You are advised to take TIZANIDINE+ACECLOFENAC for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience common side effects such as nausea, vomiting, stomach pain, loss of appetite, heartburn, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. TIZANIDINE+ACECLOFENAC may cause drowsiness and dizziness, so drive with caution. TIZANIDINE+ACECLOFENAC is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol with TIZANIDINE+ACECLOFENAC as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any interactions.

Uses of TIZANIDINE+ACECLOFENAC

Treatment of Pain and inflammation associated with musculoskeletal and joint disorders.

Medicinal Benefits

TIZANIDINE+ACECLOFENAC is a combination of two drugs: Tizanidine and Aceclofenac. TIZANIDINE+ACECLOFENAC is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, and headache. Tizanidine is a muscle relaxant that works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac is an analgesic that works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins, which are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, TIZANIDINE+ACECLOFENAC helps in relieving pain due to muscle spasms.

Directions for Use

Swallow TIZANIDINE+ACECLOFENAC as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of TIZANIDINE+ACECLOFENAC

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Loss of appetite
  • Heartburn

Drug Warnings

Do not take TIZANIDINE+ACECLOFENAC if you are allergic to any of its components. Inform your doctor if you have/ had high blood pressure, heart problems, stomach ulcer or perforation, bleeding problems such as bleeding from the stomach, intestine or brain, bypass surgery, heart attack, blood circulation problems, or inflammation of the intestine, high cholesterol, diabetes, asthma, inflammatory bowel disease, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. TIZANIDINE+ACECLOFENAC may cause drowsiness and dizziness, so drive only if you are alert. TIZANIDINE+ACECLOFENAC is not recommended for children as safety and effectiveness have not been established. Stop taking TIZANIDINE+ACECLOFENAC and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools.

Drug Interactions

Drug-Drug Interactions: TIZANIDINE+ACECLOFENAC may interact with pain killers (hydrocodone), anti-depressants (citalopram, escitalopram, duloxetine, fluoxetine, fluvoxamine, paroxetine, sertraline, lithium), hypnotic (zolpidem), anti-convulsant (pregabalin), antihistamine (diphenhydramine)

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have/had stomach ulcer or perforation, bleeding problems, bypass surgery, heart attack, blood circulation problems, heart problems, inflammation of intestines, anaemia, severe kidney or liver problems.

Drug-Drug Interactions Checker List:

  • HYDROCODONE
  • CITALOPRAM
  • ESCITALOPRAM
  • DULOXETINE
  • FLUOXETINE
  • FLUVOXAMINE
  • PAROXETINE
  • SERTRALINE
  • LITHIUM
  • ZOLPIDEM
  • PREGABALIN
  • DIPHENHYDRAMINE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol while taking TIZANIDINE+ACECLOFENAC as it may cause increased drowsiness. It may also increase the risk of stomach bleeding.

    • Safety Warning

      Pregnancy

      caution

      Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Consult your doctor if you are breastfeeding; your doctor will decide whether TIZANIDINE+ACECLOFENAC can be taken by breastfeeding mothers or not.

    • Safety Warning

      Driving

      caution

      TIZANIDINE+ACECLOFENAC may cause dizziness. Do not drive or operate machinery unless you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

    • Safety Warning

      Children

      unsafe

      TIZANIDINE+ACECLOFENAC is not recommended for children as safety and effectiveness are not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.

    • Massages can also be helpful.

    • Rest well, get plenty of sleep.

    • To avoid developing pressure sores, change your position at least every two hours.

    • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.

    • Stay hydrated, drink plenty of water.

    Patients Concern

    Disease/Condition Glossary

    Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific body area). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, and arthritis.

    Arthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.

    FAQs

    TIZANIDINE+ACECLOFENAC is used to treat pain and inflammation associated with musculoskeletal and joint disorders.

    TIZANIDINE+ACECLOFENAC contains Tizanidine and Aceclofenac. Tizanidine works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac works by blocking the effect of prostaglandins, thereby reduces mild to moderate pain and inflammation.

    TIZANIDINE+ACECLOFENAC is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Arthritis is the tenderness and swelling in the joints.

    Diarrhoea might be a side-effect of TIZANIDINE+ACECLOFENAC. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

    Dry mouth could be a side-effect of TIZANIDINE+ACECLOFENAC. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevents drying of the mouth.

    Taking TIZANIDINE+ACECLOFENAC can elevate symptoms of gastric ulcer and bleeding. So, talk to your doctor before taking TIZANIDINE+ACECLOFENAC if you have gastrointestinal bleeding or other bleeding problems like haemophilia before using TIZANIDINE+ACECLOFENAC.

    TIZANIDINE+ACECLOFENAC and Hifenac-MR are similar, as they relieve pain and inflammation but differ in their active components.

    Yes, TIZANIDINE+ACECLOFENAC is a painkiller. However, it is not meant for every kind of pain. Use it as prescribed to avoid side effects.

    You are not recommended to take TIZANIDINE+ACECLOFENAC with other painkillers, particularly NSAIDs, as it can increase the risk of side effects like stomach irritation or bleeding. If you are allergic to painkillers or NSAIDs, you should avoid using TIZANIDINE+ACECLOFENAC. Always check with your doctor before taking TIZANIDINE+ACECLOFENAC with other medicines.

    Take TIZANIDINE+ACECLOFENAC only as prescribed by your doctor. Do not adjust the dose without consulting them. If the pain persists, consult your doctor for further guidance.

    TIZANIDINE+ACECLOFENAC contains Aceclofenac, and Tizanidine, making it effective for pain relief and muscle relaxation. Zerodol-SP, on the other hand, includes Aceclofenac, Paracetamol, and Serratiopeptidase, which helps reduce pain, inflammation, and swelling. Both should be used as directed by a doctor.

    Diabetic patients can use TIZANIDINE+ACECLOFENAC, but it should be taken with caution as it may impact blood sugar levels. Therefore, please consult a doctor before using TIZANIDINE+ACECLOFENAC to ensure its safety for your condition. Regular monitoring of blood sugar is recommended.

    You are recommended to consult a doctor before taking TIZANIDINE+ACECLOFENAC with paracetamol or other medicines to avoid potential interactions.

    TIZANIDINE+ACECLOFENAC may cause drowsiness as it is one of its common side effects. However, please consult a doctor if this side effect persists for longer durations.

    Yes, the use of TIZANIDINE+ACECLOFENAC can cause nausea and vomiting. Take it with milk, food, or antacids to avoid nausea. Avoid intake of fried or fatty food along with TIZANIDINE+ACECLOFENAC. If vomiting occurs, drink plenty of water or other fluids by taking small frequent sips. If vomiting persists, consult your doctor.

    You are advised to take TIZANIDINE+ACECLOFENAC preferably after meals to minimize the risk of stomach discomfort. However, always follow your doctor's instructions.

    TIZANIDINE+ACECLOFENAC usually starts working within 20-30 minutes of taking it, though the onset may vary depending on individual health conditions.

    TIZANIDINE+ACECLOFENAC contains aceclofenac and tizanidine as its active components.

    Do not take higher than the recommended dose of TIZANIDINE+ACECLOFENAC as it can lead to increased side effects. Therefore, do not exceed the recommended dose. If your symptoms worsen, please consult your doctor.

    Store TIZANIDINE+ACECLOFENAC at room temperature in a cool and dry place as advised on the label. Protect from light and moisture. Keep it out of reach of children.

    TIZANIDINE+ACECLOFENAC is safe when used as per the dose and duration advised by a doctor.

    TIZANIDINE+ACECLOFENAC is contraindicated in individuals with known allergies to its ingredients, or patients with high blood pressure, heart problems, stomach ulcers, bleeding disorders, inflammatory bowel disease, high cholesterol, diabetes, asthma, or liver and kidney issues. TIZANIDINE+ACECLOFENAC is not recommended for children, and you should consult your doctor if you are pregnant or breastfeeding.

    You are recommended not to stop taking TIZANIDINE+ACECLOFENAC without consulting your doctor as stopping it suddenly can cause adverse effects. Therefore, continue taking TIZANIDINE+ACECLOFENAC for the duration prescribed and if you experience any difficulty while taking TIZANIDINE+ACECLOFENAC, consult your doctor so that the dose may be reduced gradually.

    Take TIZANIDINE+ACECLOFENAC as directed by your doctor. Swallow TIZANIDINE+ACECLOFENAC whole with a glass of water; do not crush, chew, or break it.

    You are recommended to avoid alcohol while taking TIZANIDINE+ACECLOFENAC, as it may cause excessive drowsiness and increase the risk of stomach bleeding. Please, consult the doctor if you have any concerns.

    Pregnant women should consult a doctor before taking TIZANIDINE+ACECLOFENAC. Your doctor prescribes TIZANIDINE+ACECLOFENAC only when the benefits outweigh the risks. Do not self-medicate.

    If you miss a dose of TIZANIDINE+ACECLOFENAC, take it as soon as you remember and if it is the time for the next dose, skip the missed dose and continue with the regular dose. Avoid taking double dose to make up for the missed one.

    TIZANIDINE+ACECLOFENAC may cause side effects such as nausea, vomiting, stomach pain, diarrhoea, loss of appetite, and heartburn. These do not require any medical treatment as they will gradually reduce over time. Consult a doctor if these side effects persist for longer durations.

    Available Medicines for

    TIZANIDINE+ACECLOFENAC

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