Tixagevimab+cilgavimab
About Tixagevimab+cilgavimab
Tixagevimab+cilgavimab belongs to the group of monoclonal antibodies used in the prevention of COVID-19 in people older than 12years and weighing at least 40kgs, who are not currently infected and have not been infected with COVID-19 in the past. It is used in individuals who are immunocompromised or are unable to receive the COVID-19 vaccine due to allergy to the vaccine.
Tixagevimab+cilgavimab contains Tixagevimab and Cilgavimab that works by preventing the viral cells from entering and infecting the human cells.
A qualified healthcare professional will administer Tixagevimab+cilgavimab. Do not self-administer. In some cases, Tixagevimab+cilgavimab may cause certain common side effects such as pain, redness and soreness at the injection site. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.
It is advisable to inform the doctor if you are allergic to any of its components. Keep your doctor informed about your medical history and medications, especially if you are taking blood thinners or if you have/had bleeding problems, heart attack/stroke, or heart problems. Consult your doctor if you are pregnant, planning to get pregnant or are breastfeeding.
Uses of Tixagevimab+cilgavimab
Medicinal Benefits
Tixagevimab+cilgavimab contains Tixagevimab and Cilgavimab used in the prevention of COVID-19 in people older than 12years and weighing at least 40kgs, who are not currently infected and have not been infected with COVID-19 in the past. It is used in individuals who are immunocompromised or are unable to receive the COVID-19 vaccine due to allergy to the vaccine. Tixagevimab+cilgavimab works by using monoclonal proteins to imitate the natural defence mechanisms of the body. The coronavirus contains a capsid with spike proteins, through which it penetrates into the body to cause infection. Tixagevimab+cilgavimab binds to the spike protein of the virus at two different sites as it contains two different monoclonal antibodies. As it attaches to two different parts of the spike protein, it prevents the viral cells from entering and infecting human cells.
Directions for Use
Storage
Side Effects of Tixagevimab+cilgavimab
- Redness
- Soreness
- Pain at the injection site
Drug Warnings
It is advisable to inform the doctor if you are allergic to any of its components. Keep your doctor informed if you suffer from HIV, asthma, cancer, liver disease, kidney problems, heart disease, epilepsy or a disease of the veins. Offer a detailed medical and vaccination history. Inform the doctor especially if you are on any radiotherapy, immunosuppressant drugs, blood thinners or any other medicines or herbal supplements. Consult your doctor if you are pregnant, planning to get pregnant or are breastfeeding.
Drug Interactions
Drug-Drug Interactions: Tixagevimab+cilgavimab may interact with anticoagulants (warfarin, acenocoumarol) and statins (atorvastatin, rosuvastatin).
Drug-Food Interactions: Tixagevimab+cilgavimab may interact with ethanol.
Drug-Disease Interactions: Tixagevimab+cilgavimab should be used with caution in patients with a known hypersensitivity disorder, HIV, asthma, cancer, liver disease, kidney problems, heart disease, epilepsy or a disease of the veins.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionIt is not recommended to consume alcohol with Tixagevimab+cilgavimab. Please consult your doctor if you have any concerns.
Pregnancy
cautionNot enough studies exist to ascertain the effect of Tixagevimab+cilgavimab on pregnancy. Please consult your doctor if you have any concerns.
Breast Feeding
cautionNot enough studies exist to ascertain the effect of Tixagevimab+cilgavimab on nursing. Please consult your doctor in case of any concerns.
Driving
cautionIt is not known if Tixagevimab+cilgavimab affects your ability to drive. Drive only if you are alert.
Liver
cautionExercise caution before using Tixagevimab+cilgavimab in case of established liver disease. Please consult your doctor to address any concerns.
Kidney
cautionExercise caution before using Tixagevimab+cilgavimab in case of established kidney disease. Please consult your doctor to address any concerns.
Children
unsafeTixagevimab+cilgavimab is not recommended for children below 12years and those weighing below 40kgs. Please consult your doctor in case of any concerns.
Habit Forming
Diet & Lifestyle Advise
- Keep a healthy state of mind. Fear is one of the biggest causes of decreased immunity. See a therapist if you feel the need.
- Meditation, music and yoga have also proven very effective in helping with mental health.
- Keep yourself at a safe distance from people.
- Always sneeze or cough into your elbow and keep a handkerchief on you.
- Wash your hands with soap and water and keep yourself clean.
- Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. Load up on Vitamin-C rich citrus fruit for enhanced immunity.
- Do not forget to take your Vitamin B complex and Vitamin C supplements every day as these are essential for the body and immunity.
- Steam inhalation for 3-5 minutes every day and salt-water gargle with warm water has been proven very effective in keeping respiratory infections at bay and in promoting health.
- Stay hydrated by drinking plenty of water as dehydration is often seen in pneumonia.
- Avoid tobacco use as smoking hampers lung health and makes breathing even more difficult.
Special Advise
- In case of a fever or rash following Tixagevimab+cilgavimab, do not use any antipyretic or anti-allergic medicines without consulting the doctor.
Patients Concern
Disease/Condition Glossary
Coronavirus Disease: Coronavirus disease is an infection caused by the SARS-CoV-2 virus. Coronavirus belongs to a group of RNA viruses and has crown-like projections on the surface of the pathogen. The virus transmits through droplets generated from an infectious person’s cough, sneeze or heavy breathing. The common symptoms of coronavirus disease are dry cough, tiredness, breathlessness, fever, loss of sense of taste and smell, diarrhoea, body pains, headache, and sore throat.
FAQs
Tixagevimab+cilgavimab belongs to the group of monoclonal antibodies used in the prevention of COVID-19 in people older than 12 years and weighing at least 40kgs, who are not currently infected and have not been infected with COVID-19 in the past. It is used in individuals who are immunocompromised or are unable to receive the COVID-19 vaccine due to allergy to the vaccine.
Tixagevimab+cilgavimab works by inducing an antibody response in the body by instilling monoclonal antibodies that mimic the natural defences of the body.
Tixagevimab+cilgavimab is found to be effective in preventing covid for at least 6 months.
Only an RT-PCR test can determine whether or not you have COVID. While a loss of smell has been noted as a common symptom, the new variant does not cause a loss of smell.
Not enough literature exists to ascertain the effects of Tixagevimab+cilgavimab on fertility. Please consult your doctor in case of any concerns.
Vaccines stimulate the body to make its own antibodies against infection. On the other hand, monoclonal antibodies deliver lab-made antibodies against the virus.
Remdesivir is an antiviral that functions to kill the virus. On the other hand, Tixagevimab+cilgavimab augments the body’s natural immunity against the virus by attaching to its structure. Thereby, prevents infection.