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Sumatriptan+naproxen Sodium

About Sumatriptan+naproxen Sodium

Sumatriptan+naproxen Sodium is used to prevent migraine symptoms such as headache, nausea, and vomiting. Migraine is a neurological condition characterised by an intense pulsating, throbbing, pounding, debilitating headache that usually occurs on one side of the head; however, it can occur on both sides or shift. Hormonal changes, stress, bright lights, loud sounds, and certain foods and drinks can trigger migraine headaches.

Sumatriptan+naproxen Sodium is a combination of two drugs: Sumatriptan and Naproxen sodium. Sumatriptan acts on the serotonin (5-HT) receptors in the brain, thereby causing the narrowing of the brain's blood vessels and affecting the blood flow patterns associated with headaches. Naproxen sodium is a painkiller that works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) and prostaglandins (PG) responsible for pain/inflammation. Thus, Sumatriptan+naproxen Sodium prevents symptoms of migraine.

Take Sumatriptan+naproxen Sodium as prescribed. You are advised to take Sumatriptan+naproxen Sodium as long as your doctor has recommended it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as dizziness, sleepiness, nausea, chest discomfort, dry mouth, irregular heartbeats, and heartburn. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently. 

Sumatriptan+naproxen Sodium can increase the risk of fatal heart attack or stroke, gastrointestinal bleeding, ulceration, and perforation of the stomach and intestines. Consult your doctor before taking Sumatriptan+naproxen Sodium if you are pregnant or breastfeeding. Sumatriptan+naproxen Sodium should not be taken during the third trimester of pregnancy. Sumatriptan+naproxen Sodium may cause drowsiness and dizziness, so drive with caution. Sumatriptan+naproxen Sodium is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with Sumatriptan+naproxen Sodium as it could lead to increased drowsiness and dizziness.

Uses of Sumatriptan+naproxen Sodium

Treatment of Migraine

Medicinal Benefits

Sumatriptan+naproxen Sodium is a combination of two drugs: Sumatriptan and Naproxen sodium. Sumatriptan+naproxen Sodium is indicated for the acute treatment of migraine with or without aura. Sumatriptan is a serotonin receptor agonist that acts on the serotonin (5-HT) receptors located in the brain, which causes the narrowing of the brain's blood vessels, thereby affecting the blood flow patterns with a headache. Naproxen sodium is a pain killer which works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins (PG). By blocking the effect of COX enzymes, fewer PGs are produced, thereby reducing pain in migraine.

Directions for Use

Take Sumatriptan+naproxen Sodium with or without food as advised by the doctor. Swallow it whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sumatriptan+naproxen Sodium

  • Dizziness

  • Sleepiness

  • Nausea

  • Chest discomfort

  • Dry mouth

  • Irregular heartbeats

  • Heartburn

Drug Warnings

Do not take Sumatriptan+naproxen Sodium if you are allergic to any of its contents; if you have had any recent heart surgery or stroke, blood circulation problems, heart problems, narrowing of blood vessels to the stomach, legs, arms or kidneys, or uncontrolled high blood pressure; if you are taking MAO inhibitors/antidepressants or have taken them in the last 14 days; or if you have taken 5-HT agonists called triptan or ergotamine in the last 24 hours. Be cautious as Sumatriptan+naproxen Sodium can increase the risk of fatal heart attack or stroke, gastrointestinal bleeding, ulceration, stomach and intestine perforation. Inform your doctor before taking Sumatriptan+naproxen Sodium if you have high blood pressure, asthma, diabetes, epilepsy, overweight, heart, kidney or liver problems. Consult your doctor before taking Sumatriptan+naproxen Sodium if you are pregnant or breastfeeding. Sumatriptan+naproxen Sodium should not be taken during the third trimester of pregnancy. Sumatriptan+naproxen Sodium may cause drowsiness and dizziness, so drive only if you are alert. Sumatriptan+naproxen Sodium should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Sumatriptan+naproxen Sodium as it could lead to increased drowsiness. Stop taking Sumatriptan+naproxen Sodium and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach such as blood in stools.

Drug Interactions

Drug-Drug Interactions: Sumatriptan+naproxen Sodium may have interaction with blood thinners (warfarin, aspirin), cardiac glycoside (digoxin), anti-psychotic (lithium), anti-rheumatoid (methotrexate), anti-depressant (citalopram, duloxetine, desvenlafaxine, fluoxetine), anti-hypertensive (metoprolol), an antacid (omeprazole). 

Drug-Food Interactions: Avoid the consumption of alcohol, smoking, and caffeinated products. Do not consume grapefruit while taking Sumatriptan+naproxen Sodium.

Drug-Disease Interactions: Inform your doctor if you have asthma, fluid retention, gastrointestinal toxicity, renal toxicity, cardiovascular disease, anaemia, heart failure, liver toxicity, high blood pressure, seizure, hyperkalemia (high levels of potassium), and platelet aggregation inhibition.

Drug-Drug Interactions Checker List:

  • WARFARIN
  • ASPIRIN
  • LITHIUM
  • METHOTREXATE
  • DIGITOXIN
  • CITALOPRAM
  • DULOXETINE
  • FLUOXETINE
  • DESVENLAFAXINE
  • METOPROLOL
  • OMEPRAZOLE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol while taking Sumatriptan+naproxen Sodium as it may cause increased drowsiness.

    • Safety Warning

      Pregnancy

      caution

      Sumatriptan+naproxen Sodium should be used during the first and second trimester of pregnancy only if the benefits outweigh the risks. Sumatriptan+naproxen Sodium should not be taken during the third trimester of pregnancy.

    • Safety Warning

      Breast Feeding

      caution

      Sumatriptan+naproxen Sodium may pass into breastmilk and harm the baby. Please consult your doctor before taking Sumatriptan+naproxen Sodium if you are breastfeeding; your doctor will decide whether Sumatriptan+naproxen Sodium can be taken by breastfeeding mothers or not.

    • Safety Warning

      Driving

      caution

      Sumatriptan+naproxen Sodium may cause dizziness, weakness and drowsiness. Do not drive or operate machinery unless you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      unsafe

      Sumatriptan+naproxen Sodium is not recommended for children as the safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Maintaining a healthy diet and exercising regularly helps in improving overall health and boosts self-esteem.

    • Avoid bright lights, loud noise, and extreme temperatures.

    • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

    • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

    • Massage your scalp to ease the pain.

    • Lie down in a quiet, darkroom.

    • Place a cold cloth over your forehead or neck.

    • Avoid smoking, alcohol, and caffeinated drinks. 

    • Learn what triggers your migraine and try avoiding them.

    • Stay hydrated. Drink plenty of fluids.

    • Learn relaxation skills as they help in reducing stress.

    Patients Concern

    Disease/Condition Glossary

    Migraine: Migraine is a neurological condition that is characterised by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, and certain foods and drinks can trigger migraine headaches. Warning symptoms precede migraine headache one or two days before the headache itself. The warning symptoms include food cravings, depression, fatigue, hyperactivity, irritability, and neck stiffness. Symptoms of migraine include throbbing pain in one particular area with varying intensity, nausea, vomiting, numbness or tingling sensation, difficulty speaking, and sensitivity to sound and light.

    FAQs

    Sumatriptan+naproxen Sodium is used to prevent migraine symptoms such as headache, nausea, and vomiting.

    Sumatriptan+naproxen Sodium contains Sumatriptan and Naproxen sodium. Sumatriptan acts on the serotonin (5-HT) receptors located in the brain; this causes narrowing of the blood vessels in the brain, and also affects the blood flow patterns associated with headache. Naproxen sodium works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins (PG). By blocking the effect of COX enzymes, lesser PGs are produced, which reduces mild to moderate pain.

    Dry mouth could be a side-effect of Sumatriptan+naproxen Sodium. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

    Sumatriptan+naproxen Sodium treats a headache that has already begun but does not prevent or reduce the attacks. Sumatriptan+naproxen Sodium should not be used to treat cluster headache or other types of headache, which may cause loss of movement on one side of the body.

    Sumatriptan+naproxen Sodium contains Naproxen sodium, an NSAID. Therefore, consult your doctor before taking any pain killer medicines, fever-reducing medicines, medicines for cold or sleeping problems along with Sumatriptan+naproxen Sodium as they may also contain NSAID.

    Talk to your doctor before taking Sumatriptan+naproxen Sodium with anti-hypertensive medicines as they may cause impaired response when taken with painkiller. Regular monitoring of blood pressure levels is advised while taking Sumatriptan+naproxen Sodium if you have high blood pressure. Sumatriptan+naproxen Sodium should not be taken if you have uncontrolled high blood pressure.

    Sumatriptan+naproxen Sodium contains a pain killer, which might increase the risk of gastrointestinal adverse effects such as ulceration, bleeding, and perforation of intestines or stomach. Therefore, avoid taking Sumatriptan+naproxen Sodium if you have stomach ulcers unless prescribed by the doctor.

    No, Sumatriptan+naproxen Sodium is not an antibiotic. It is a combination medication that contains sumatriptan (selective serotonin receptor agonists) and naproxen sodium (nonsteroidal anti-inflammatory drugs) used to prevent migraine symptoms such as headache, nausea, and vomiting.

    Sumatriptan+naproxen Sodium is not intended for any type of headache other than migraine headaches. If you experience a headache which is not due to migraine, consult the doctor to determine the suitable treatment for your specific condition.

    Yes, Sumatriptan+naproxen Sodium may cause sleepiness as a common side effect. If you experience sleepiness, avoid driving and operating heavy machinery.

    Sumatriptan+naproxen Sodium may cause medication overuse headache in some people when too many doses of the medication are used. Therefore, take Sumatriptan+naproxen Sodium only in the dose prescribed by the doctor to prevent adverse effects and consult the doctor if your headache worsens.

    Sumatriptan+naproxen Sodium contains sumatriptan and naproxen sodium as active ingredients. It is used to prevent migraine symptoms such as headache, nausea, and vomiting.

    The side effects of Sumatriptan+naproxen Sodium include sleepiness, nausea, dizziness, chest discomfort, dry mouth, irregular heartbeats, and heartburn. Consult the doctor if any of these side effects persist or worsen.

    No, do not take a higher than the recommended dose of Sumatriptan+naproxen Sodium as it might cause an overdose. Overdose symptoms include tremors, convulsions, paralysis, inactivity, ptosis (drooping of upper eyelid), redness of the extremities, abnormal breathing, cyanosis (bluish-purple colouration of skin), ataxia (loss of muscle coordination), dilated pupils, excessive salivation, and tearing. Consult the doctor if you have overdosed or if you experience any of these symptoms.

    Sumatriptan+naproxen Sodium should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.

    You may stop taking Sumatriptan+naproxen Sodium once your migraine symptoms are relieved. However, always follow the doctor's advice and consult the doctor before discontinuing the medication.

    The exact cause of migraines is unknown, but a family history of migraines increases the likelihood of experiencing them. The migraine triggers include hormonal changes, sleep changes, stress, and tiredness, skipping meals, excessive caffeine consumption, and not getting enough exercise.

    Sumatriptan+naproxen Sodium is not recommended for children below 12 years as its safety and efficacy were not established. Consult the doctor if you have any concerns regarding its use for children.

    No, Sumatriptan+naproxen Sodium is not intended to treat throat infections. It is specifically used to treat headaches associated with migraines. If you have throat infections, it is best to consult the doctor for appropriate treatment.

    Sumatriptan+naproxen Sodium should be taken as soon as you experience the onset of a migraine. It is most effective when taken early in the course of a migraine attack. Always follow the doctor's instructions regarding the timing and dosage.

    Yes, Sumatriptan+naproxen Sodium is safe if taken in the dose and duration prescribed by the doctor.

    The recommended dose of Sumatriptan+naproxen Sodium is one tablet for the acute treatment of a migraine. If symptoms persist, a second dose may be taken after at least 2 hours. However, do not exceed two doses in a 24-hour period. Always follow the doctor's specific instructions for the correct dosage.

    Sumatriptan+naproxen Sodium starts to work within 30-60 minutes and it may take 2 hours to reduce headache. However, it may vary depending on the individual.

    Available Medicines for

    Sumatriptan+naproxen Sodium

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