Pethidine

Pethidine tablets should not be given to you if you are an asthmatic, have breathing problems or have severe disease relating to the lungs, suffering from a head injury or brain tumour, or have an irregular heartbeat (arrhythmia), or are undergoing treatment with, or have finished treatment in the last two weeks with, monoamine oxidase (MAO) inhibitors (e.g. phenelzine, tranylcypromine, moclobemide), have severe liver or kidney disease, have blood-thinning problems, or are receiving treatment for this disorder (e.g. warfarin), have alcohol use disorder, have a blockage in the stomach and intestine (severe constipation) or have severe pain in the stomach with bloating, gut cramps and vomiting (paralytic ileus). So, before taking the Pethidine, let your doctor know about all your medical conditions, sensitivities, and all medications you are using.

Drug-Drug Interactions: Pethidine may have interaction with sedative-hypnotics (e.g. zolpidem), benzodiazepines (e.g. lorazepam, alprazolam), anti-depression medications (e.g. duloxetine, fluoxetine), skeletal muscle relaxants (e.g. cyclobenzaprine), anticonvulsants (e.g. gabapentin) and monoamine oxidase inhibitors (e.g. phenelzine, tranylcypromine, moclobemide) and blood thinners (warfarin).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Pethidine may interact with various disease conditions, including asthma, breathing problems, diabetes, phaeochromocytoma (a tumour of the adrenal gland), convulsive disorder (fits), head injury or brain tumour, irregular heartbeat (arrhythmia), severe liver or kidney disease, alcohol use disorder, blockage in the stomach and intestine (severe constipation), severe pain in the abdomen with bloating, gut cramps, and vomiting (paralytic ileus).

• Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
• Performing yoga may also help in improving joint flexibility and pain management.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
• Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20 minutes regularly.
• De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
• Acupuncture, massage and physical therapy may also be helpful.
• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
• Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
• Avoid smoking and alcohol consumption.