Paracetamol+triprolidine+phenylephrine
About Paracetamol+triprolidine+phenylephrine
Paracetamol+phenylephrine+triprolidine belongs to the class of medications called ‘cough and cold preparations’ used to treat the common cold and allergic symptoms such as the runny nose, sneezing, itchy or watery eyes, and blocked nose. The common cold is an infection of the nose and throat caused by viruses. Allergies are immune system reactions to foreign bodies or allergens such as certain foods, chemicals, pet dander, or pollen.
Paracetamol+phenylephrine+triprolidine is a combination of three medicines: Paracetamol, Triprolidine, and Phenylephrine. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever). It works by inhibiting prostaglandin's production (chemical messengers) that are responsible for pain and fever. Triprolidine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels of nasal passage and airways.
You should take this medicine as prescribed by your doctor. The common side-effects of Paracetamol+phenylephrine+triprolidine are nausea, vomiting, dizziness, drowsiness, nervousness, and trouble sleeping. These side-effects are usually mild and don’t require medical attention. However, consult your doctor immediately if any of these side-effects persist or get worsen.
Do not use Paracetamol+phenylephrine+triprolidine if you are allergic to Paracetamol, Triprolidine, Phenylephrine, or any other contents in it. Paracetamol+phenylephrine+triprolidine is not recommended for use in patients suffering from constipation, inability to urinate, stomach blockage, uncontrolled asthma, glaucoma (increased pressure in the eye), high blood pressure, heart diseases, hyperthyroidism (overactive thyroid), diabetes, or intolerance to sugars. Do not take Paracetamol+phenylephrine+triprolidine if you have taken MAO inhibitors (antidepressants) in the last 14 days. Inform your doctor if you are pregnant or breastfeeding.
Uses of Paracetamol+triprolidine+phenylephrine
Medicinal Benefits
Paracetamol+phenylephrine+triprolidine is a combination of three medicines: Paracetamol, Triprolidine, and Phenylephrine. Paracetamol is an analgesic (relieves pain) and works by inhibiting the production of prostaglandins (chemical messengers) that are responsible for pain. It also has an antipyretic effect (reduces fever). Triprolidine is an antihistamine (anti-allergic drug) that blocks histamine, a substance responsible for causing allergic reactions. It also provides relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels of nasal passage and airways. Together, Paracetamol+phenylephrine+triprolidine can effectively reduce the symptoms of common cold and allergies.
Directions for Use
Storage
Side Effects of Paracetamol+triprolidine+phenylephrine
- Nausea
- Vomiting
- Dizziness
- Drowsiness
- Nervousness
- Trouble sleeping
- Blurred vision
- Dry mouth
Drug Warnings
Paracetamol+phenylephrine+triprolidine should be used with caution in patients with breathing problems, glaucoma (increased pressure in the eye), heart problems, hypertension (high blood pressure), kidney problems, liver disease, seizures (fits), stomach blockage), hyperthyroidism (overactive thyroid), and an enlarged prostate gland (difficulty urinating). Paracetamol+phenylephrine+triprolidine contains sucrose, so use this medicine with caution in patients with diabetes and intolerance to sugars. Paracetamol+phenylephrine+triprolidine may cause drowsiness, so do not take alcohol as it causes excessive drowsiness. Also, do not drive or operate heavy machinery if you are drowsy. It should be used with caution in children and elderly patients as they are more prone to side-effects. Do not take Paracetamol+phenylephrine+triprolidine if you have taken antidepressants or medicines to treat Parkinson’s disease in the last 14 days.
Drug Interactions
Drug-Drug Interactions: Paracetamol+phenylephrine+triprolidine may interact with other antihistamines (cetirizine and diphenhydramine), medicines used to treat high blood pressure (guanethidine, methyldopa, atenolol, and nifedipine), anticoagulant (warfarin), a medicine used to treat high cholesterol (cholestyramine), a medicine used to treat HIV (zidovudine), anti-emetic drugs (domperidone and metoclopramide), MAO inhibitors (isocarboxazid. linezolid, methylene blue, phenelzine, selegiline, and tranylcypromine, etc.), birth control pills, medications used to treat cough (codeine and hydrocodone), sedatives (alprazolam, lorazepam, and zolpidem), and muscle relaxants (carisoprodol and cyclobenzaprine).
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Paracetamol+phenylephrine+triprolidine should be used with caution in patients with constipation, inability to urinate, a stomach blockage, uncontrolled asthma, diabetes, glaucoma (increased pressure in the eye), high blood pressure, heart diseases, and hyperthyroidism (overactive thyroid).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAlcohol consumption may increase the risk of side-effects such as drowsiness.
Pregnancy
unsafeParacetamol+phenylephrine+triprolidine is a category C medicine and may cause toxic effects to the unborn baby. When clinically needed, Paracetamol+phenylephrine+triprolidine is given to pregnant women after doing a risk/benefit assessment by a doctor.
Breast Feeding
unsafeParacetamol+phenylephrine+triprolidine may pass into breast milk. So, it should be used with caution in breastfeeding mothers.
Driving
cautionParacetamol+phenylephrine+triprolidine may cause drowsiness. So, avoid driving or operating heavy machinery while using this medicine if you are drowsy.
Liver
cautionParacetamol+phenylephrine+triprolidine should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.
Kidney
cautionParacetamol+phenylephrine+triprolidine should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.
Children
cautionParacetamol+phenylephrine+triprolidine should be used with caution in children as they are more prone to side-effects. The dose may have to be adjusted by your doctor.
Habit Forming
Diet & Lifestyle Advise
- Staying hydrated is vital for those with a cough or cold. Drinking liquids at room temperature can alleviate cough, runny nose, and sneezing.
- The immune system is affected by stress and raises the risk of being sick. An individual can exercise regularly, meditate, do deep breathing, and try progressive muscle relaxation techniques to relieve stress.
- To stay fit and safe, try to sleep at least 8 hours each night.
- It is advised to avoid contact with known allergens (allergy-causing agents) such as pollen, dust, etc. Certain food items are known to cause allergies to you.
Special Advise
Paracetamol+phenylephrine+triprolidine may interfere with certain laboratory tests such as brain scan for Parkinson's disease and urine drug screening tests, leading to false test results. So, inform your doctor that you are using this medicine before undergoing the tests.
Patients Concern
Disease/Condition Glossary
Common cold: The common cold is an infection caused by the virus, mainly known as ‘rhinoviruses’, affecting the nose and throat (upper respiratory tract). Children younger than 6 years are at the most significant risk of colds, but healthy adults can also be affected to have 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like pollutants, dust, etc. The symptoms of the common cold include sneezing, sore throat, cough, congestion, mild body pains, low fever, mild headache, feeling unwell, stuffy, or runny nose. In some cases, the discharge from the nose may become thicker and yellow or green, which is not an indication of bacterial infection.
Allergies: It occurs when foreign elements that cause allergy-causing agents (allergens) attack and invades our body, thereby causing the release of histamines. This chemical messenger 'histamines' causes swelling, inflammation, redness, itchiness, itchy/watery nose and throat, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet danders, dust, pollen hairs, seasonal allergies like hay fever, etc.
FAQs
Paracetamol+phenylephrine+triprolidine is used to treat the common cold and allergic symptoms such as the runny nose, sneezing, itchy or watery eyes, and blocked nose.
Paracetamol+phenylephrine+triprolidine is a combination of three medicines: Paracetamol, Triprolidine, and Phenylephrine. Paracetamol blocks the action of chemical messengers that cause pain and fever. Triprolidine blocks the action of histamines that cause allergic reactions. Phenylephrine reduces swelling of the blood vessels in the nasal passages. Together, Paracetamol+phenylephrine+triprolidine can effectively treat symptoms of allergy and the common cold.
Paracetamol+phenylephrine+triprolidine may cause drowsiness and dizziness. So, it is advised to refrain from activities such as driving or operating heavy machinery until you are alert.
It is not recommended to use cetirizine along with Paracetamol+phenylephrine+triprolidine as it may increase side-effects such as drowsiness and dizziness. So, it is advised to consult a doctor before using any medicines while taking Paracetamol+phenylephrine+triprolidine.
Paracetamol+phenylephrine+triprolidine should not be used if you have taken antidepressants or drugs used to treat Parkinson's disease in the last 14 days. So, it is always advised to inform your doctor about all the prescription, non-prescription, and dietary supplements you are taking, to identify any interactions with the Paracetamol+phenylephrine+triprolidine.
Paracetamol+phenylephrine+triprolidine can effectively treat and provide relief from allergic symptoms such as sneezing, runny/stuffy nose, throat irritation, or watery eyes.
You are recommended not to stop taking Paracetamol+phenylephrine+triprolidine on your own without first consulting your doctor. Although Paracetamol+phenylephrine+triprolidine is generally used for short duration but continue taking it for the duration advised by your doctor. If you experience any difficulty while using Paracetamol+phenylephrine+triprolidine, please consult your doctor.
No, Paracetamol+phenylephrine+triprolidine does not work for tooth pain. If you experience tooth pain, please consult a dentist for appropriate treatment.
Take Paracetamol+phenylephrine+triprolidine with or without food as advised by your doctor. Swallow it as whole with a glass of water. Do not break, crush or chew it.
Do not take Paracetamol+phenylephrine+triprolidine if you have taken antidepressants which include MAOIs (monoamine oxidase inhibitors) in the last 14 days. Paracetamol+phenylephrine+triprolidine should be used with caution in patients with breathing problems, glaucoma (increased pressure in the eye), heart problems, hypertension (high blood pressure), kidney problems, liver disease, seizures (fits), stomach blockage), hyperthyroidism (overactive thyroid), and an enlarged prostate gland (difficulty urinating).
Store Paracetamol+phenylephrine+triprolidine at room temperature below 30°C in a dry place, protected from light. Keep it out of reach of children.
Paracetamol+phenylephrine+triprolidine may rarely cause serious side effects. If you experience allergic reactions, breathing problems, mouth ulcers, skin rash or peeling, dry mouth, vision disturbances, unexplained bleeding, fast or irregular heartbeat and recurrent fevers or infections, inform your doctor immediately.
No, taking a higher than the recommended dose may not be more effective, rather it may increase the risk of serious side effects. If your symptoms are not relieved or there is an increased severity of your symptoms after using the recommended doses, please consult your doctor.
You are recommended to use Paracetamol+phenylephrine+triprolidine with caution while breastfeeding as it may pass into the breast milk. Therefore, inform your doctor if you are breastfeeding before starting Paracetamol+phenylephrine+triprolidine.
Paracetamol+phenylephrine+triprolidine contains Paracetamol, which is known to harm the liver especially when taken in more than recommended doses. Also, avoid alcohol consumption while taking Paracetamol+phenylephrine+triprolidine, as it may further increase the risk of liver damage. Also, Paracetamol+phenylephrine+triprolidine is preferably avoided in patients with underlying liver disease. If you notice any early signs and symptoms of liver damage such as yellow skin or eyes, dark urine, fever, stomach pain, nausea, vomiting, loss of appetite, rash, fatigue (overtiredness) and abnormal liver enzymes, contact your doctor immediately.
Paracetamol+phenylephrine+triprolidine contains Paracetamol as one of its active ingredients.
No, Paracetamol+phenylephrine+triprolidine is not an antibiotic. It is a combination medicine used to relieve symptoms of common cold and allergies.
Paracetamol+phenylephrine+triprolidine is generally recommended for short term use. Do not take it for prolonged time without the advice of your doctor. Follow your doctor’s instructions.
Paracetamol+phenylephrine+triprolidine contains Triprolidine, an antihistamine as one of its active ingredients.
The side effects of Paracetamol+phenylephrine+triprolidine include nausea, vomiting, dizziness, drowsiness, trouble sleeping, nervousness, dry mouth and blurred vision. If any of these side effects persist or worsen, please consult your doctor.
