Papain+diastase+pepsin
About Papain+diastase+pepsin
Papain+diastase+pepsin belongs to the class of combination medication called 'digestive aid' primarily used to treat digestive disorders. Papain+diastase+pepsin effectively treats dyspepsia (indigestion), pancreatic insufficiency (inability to produce pancreatic enzymes), thereby relieving symptoms of indigestions like flatulence (gas), upper abdominal pain and bloating. It is also used as an appetite stimulant and relieves sour stomach and eructation (burping). Indigestion is the inability to digest food associated with pain and discomfort in the stomach due to various conditions of illness.
Papain+diastase+pepsin contains three digestive enzymes, namely: Papain, Diastase and Pepsin. Papain is a proteolytic enzyme (the breakdown of protein) extracted from the papaya plant's raw fruit. A proteolytic enzyme breaks down the proteins into simple forms called peptides and amino acids, improving digestion in infections, diarrhoea and allergies. Diastase is a starch hydrolysing enzyme, an enzyme that breaks down the starch into simple sugars. Pepsin is a proteolytic enzyme (protein-digesting) that breaks down larger protein molecules into smaller peptides (unit of protein). Thus Papain+diastase+pepsin aids in the digestion of carbohydrate, fat and protein in the various conditions of illness or post-surgery.
Please take Papain+diastase+pepsin in the dose and duration advised by your doctor based on your digestive disorder. Papain+diastase+pepsin is generally safe to use. However, some may experience side effects like abdominal pain, stomach upset, diarrhoea, painful urination, heartburn, nausea and vomiting. Although not everyone experiences these side effects, if they occur, please seek medical attention.
Let your doctor know if you are using any other medicines, herbal or vitamin supplements before you take Papain+diastase+pepsin. Inform your doctor if you have any allergic reactions to pork protein before starting Papain+diastase+pepsin. If you a history of inflammation/swelling of the pancreas (acute pancreatitis), let your doctor know about it. Intake of probiotics, prebiotics and plenty of fluids is recommended (not for kidney patient) if suffering from indigestion. Pregnant and breastfeeding women should use Papain+diastase+pepsin with proper consultation and caution.
Uses of Papain+diastase+pepsin
Medicinal Benefits
Papain+diastase+pepsin helps in relieving digestive disorders like indigestion, gas and abdominal pain and discomfort. It contains three digestive enzymes, namely: Papain, Diastase and Pepsin. Papain is a proteolytic enzyme (the breakdown of protein) that is extracted from the raw fruit of the papaya plant. Papain is also used as a folk remedy to reduce pain, inflammation and swelling. Diastase is a starch hydrolysing or amylolytic enzyme that breaks down the starch into simple sugars (maltose) for easy digestion of starch, carbohydrates, fats and proteins. It is used as a digestant to aid digestion in cases of chronic illness, stomach fullness and indigestion. Pepsin is a proteolytic enzyme (protein-digesting) that breaks down larger protein molecules into smaller peptides (a short chain of amino acids). It mimics the natural human pepsin enzyme and is used as a pancreatic enzyme replacement in pancreatic insufficiency. Thus, Papain+diastase+pepsin promotes the digestion of carbohydrates, fats and proteins and helps absorb the essential nutrients in the intestine.
Directions for Use
Storage
Side Effects of Papain+diastase+pepsin
Abdominal pain
Feeling of sickness
Stomach upset
Diarrhoea
Painful urination
Heartburn
Nausea
Vomiting
Drug Warnings
Pregnant and breastfeeding women should use Papain+diastase+pepsin with proper consultation and caution. Alcohol consumption makes the stomach to produce more acid, which can further lead to heartburn. Smoking can irritate the stomach lining; hence please avoid it. If you have had any pancreatic disorder like pancreatitis (inflammation of the pancreas) avoid intake of Papain+diastase+pepsin and consult a doctor.
Drug Interactions
Drug-Drug Interaction: Papain+diastase+pepsin may interact with anti-diabetic drugs (acarbose and miglitol).
Drug-Food Interaction: Alcohol consumption makes the stomach to produce more acid, which can further lead to heartburn.
Drug-Disease Interaction: Papain+diastase+pepsin should be cautiously administered when you have any liver or kidney diseases, diabetes and swelling/inflammation of the pancreas (acute pancreatitis).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionIt is recommended to avoid alcohol while you are being treated with Papain+diastase+pepsin. Alcohol consumption makes the stomach to produce more acid, which can further lead to heartburn.
Pregnancy
cautionThere is limited data on how the Papain+diastase+pepsin affects pregnancy. Papain+diastase+pepsin should be used during pregnancy only if the benefit outweighs the risk. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Papain+diastase+pepsin.
Breast Feeding
cautionIt is not known if Papain+diastase+pepsin is excreted into the breast milk while used by a breastfeeding mother. Please consult your doctor before taking Papain+diastase+pepsin if you are breastfeeding.
Driving
safeDo not drive or operate machinery if you experience discomfort while using Papain+diastase+pepsin until you feel better.
Liver
cautionPlease take Papain+diastase+pepsin with caution and doctor's advice if you have a history of liver diseases/conditions. Your dose may be adjusted in case of any liver impairment.
Kidney
cautionPlease take Papain+diastase+pepsin with caution and doctor's advice if you have a history of kidney diseases/conditions. Your dose may be adjusted in case of any renal impairment.
Children
cautionYour doctor will decide the dose based on your child’s age and bodyweight.
Habit Forming
Diet & Lifestyle Advise
Please take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
Eat fibre rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas to aid digestion.
Avoid intake of alcoholic beverages with Papain+diastase+pepsin as it can make you dehydrated and increase acidity.
Avoid eating too much, eating too fast, eating high-fat foods or eating during stressful situations that can burden your stomach.
Eating small meals at regular intervals so that stomach does not have to work as hard or as long.
Smoking can irritate the stomach lining, hence please avoid it.
Sleep with your head elevated (at least 6 inches) above your feet and use pillows. This helps digestive juices to flow into the intestines rather than to the oesophagus.
Patients Concern
Disease/Condition Glossary
Dyspepsia (indigestion): Indigestion is the inability to digest food that is associated with pain and discomfort in the stomach. Symptoms include bloating, abdominal pain, burning sensation in the stomach, gas, and belching.
Flatulence: It is the build-up of gas in the digestive system that can lead to abdominal discomfort.
FAQs
Papain+diastase+pepsin is used to treat digestive disorders. It effectively treats dyspepsia (indigestion), pancreatic insufficiency (inability to produce pancreatic enzymes), thereby relieving symptoms of indigestions like flatulence (gas), upper abdominal pain and bloating. It is also used as an appetite stimulant and relieves sour stomach and eructation (burping).
Papain+diastase+pepsin contains digestive enzymes, namely Papain, Diastase and Pepsin. Collectively, Papain+diastase+pepsin relieves digestive disorders and promotes the digestion by breaking down carbohydrates, fats and proteins into simpler forms.
Please let your doctor know if you have a history of allergic reactions to medicines, pork protein and inflammation of the pancreas (pancreatitis) before starting Papain+diastase+pepsin.
Do not stop using Papain+diastase+pepsin even if you feel better until the doctor's advised course is finished. Your symptoms of indigestion may improve, but the disease may not be cured completely.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
No, Indigestion occurs when an individual lacks the enzyme to digest carb, protein and fat present in the food. On the other hand, hyperacidity is the excessive formation of bile acids and stomach acid, which backflows to the food pipe, causing acid reflux and heartburn.